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Article
Evaluation of Oxidative Stress with Thyroid Function in Growth Hormone-deficient Children from Misan Government ,Iraq.

Authors: Mohammed Abdul-Mounther --- .Mohammed Abed Draweesh --- Farah Mjbaal --- Mahdi Murshd
Journal: Misan Journal of Acodemic Studies مجلة ميسان للدراسات الاكاديمية ISSN: 1994697X Year: 2017 Volume: 16 Issue: 32 Pages: 78-90
Publisher: Misan University جامعة ميسان

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Abstract

Aim: Growth hormone deficiency (GHD) is a complex endocrine syndrome, which is most commonly known to affect the pediatric population. However, adults also suffer from GHD, and it is often seen as part and parcel of the aging phenomenon. We aimed to investigate the levels and relationships of antioxidants, lipid peroxidation and thyroid function with altogether in growth hormone deficiency .Method:This study was conducted to measure a group of hormones related with infected individuals with the shortage of the growth hormone by studying 57 sample Which represents patient groups were ( 38 boys and 19 girls ) divided in to two groups according to age Group (1): consist of 26 patients (boys 14 and 12 girls ) their aged ranged from 2 to 8 years and Group (2) Consisted of 31 patients ( 24 boys and 7 girls ). Their ages ranged from 9 to 16 years in comparison with 50 samples taken from normal individuals as a control group. The concentration of hormones has been measured were human Growth hormone (hGH) Total Triidothyronin(TT3), Total Thyroxin (TT4),Free Thyroxin (FT4)Thyroid Stimulating (TSH), serum malondialdehyde (MDA) ,Vitamin C , Erythrocyte superoxide dismutase (SOD) activity, plasma Total antioxidant capacity (TAC)

Keywords

Oxidative Stress


Article
Estimation of Reference Values for Liver Function ParametersinNeonates individuals from Missan district ,S. Iraq
تقدير القيم المرجعية لوظائف فعالية الكبد لدى الاطفال حديثي الولادة من محافظة ميسان جنوب العراق

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This paper offers an insight to generalists on how to extract greater information from these tests in order to improve the investigation and management of liver disease..The activities of (total serum bilirubin (T.S.B) ,aspartate aminotransferase (AST), alanine aminotransferase (ALT), alkaline phosphatase(ALP), total proteins (TP) and albumin (ALB),. AST, ALT and bilirubin ,total protein were measured in 150 neonates (85 males and 65 females) from at Al-Sadder Teaching Hospital environs with collaborative arrangement of clinical biochemistry lab.in medicine college ,Missan University with age rangedbetween (1-4 days) were included in this study.The serum activities of the liver enzymes (AST, ALT and ALP) were found to be elevated (p≤0.001) with respect to subjects on WHO. At the same time, T.S.B was abnormally elevated (p ≤0.001) in the serum of neonates test, While theT.Premainedconstantwithout anychanging .

تم قياس مستويات نشاط كل من نسبة البلروبين الكلي, ناقلة امين الاسباراتات (AST- (Aspartate aminotransferase ناقلة امين الالانين (ALT - (Alanine aminotransferase, ,الفوسفاتاز القلوي (ALP - (Alkaline phosphatase والبروتين الكلي TP.بالاضافة الى فحص مستوى الالبومينAlb., لدى 150 حديثي الولادة ( 85ذكور و 65 إناث)الذين تراوحت اعمارهم مابين (1الى4) يوم ,والذين اخذت نماذج الدممن الاطفال الرضع في ردهات مستشفى الصدر لتعليمي في محافظة ميسان جنوب العراق وجرت القياسات في مختبرات فرع الكيمياء السريرية, كلية الطب جامعة ميسان.وجد ان النشاط الانزيميلل(AST، ALT و ALP) له قيمة معنوية احصائية مرتفعة ((p≤0.05 . وفي الوقت نفسه، ففي قياسT.S.B اظهر قيمة معنوية مرتفعة بشكل غير طبيعي ((p≤0.05 في مصل اختبار حديثي الولادة، بينما ظلت قيم الالبومين T.P Alb. ثابت دون أي تغيير ضمن القيم المرجعية للمختبر.

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