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Effectiveness of Zinc Supplementation in Regulating Serum Hormonal and Inflammatory Status in Hypothyroidism Patients

Authors: Manal A. Aziz --- Neama Yahya Habil --- Abdul Kareem S. Diab
Journal: Medical Journal of Babylon مجلة بابل الطبية ISSN: 1812156X 23126760 Year: 2016 Volume: 13 Issue: 2 Pages: 347 -353
Publisher: Babylon University جامعة بابل


This study was designed to investigate the serum level of thyroid-stimulating hormone,thyroxine, triiodothyronine, interleukin-6 and tumour necrosis factor-α” in hypothyroidism patients, and to reveal their relationship with serum zinc level in 27 patients with hypothyroidism, and 27 control group. The results disclosed that serum zinc, interleukin-6 and tumour necrosis factor-α levelsin hypothyroidism patients are significantly lower (p˂0.05) than the control group. While serum thyroid stimulating hormone level, was significantly higher in hypothyroidism patients than the control (p˂0.05). After zinc administration, the patients group showeda significant increase in “interleukin-6 and tumour necrosis factor-α” level (p˂0.05) in comparison with control group."


Zinc --- TSH --- T3 --- T4 --- Hypothyrodism --- TNF-α --- IL-6

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