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Article
HYPONATREMIA IN A GROUP OF IRAQI PATIENTS WITH STROKE

Author: Abdul-Kareem K. Al-Khazraji عبد الكريم كاظم الخزرجي
Journal: IRAQI JOURNAL OF MEDICAL SCIENCES المجلة العراقية للعلوم الطبية ISSN: P16816579,E22244719 Year: 2016 Volume: 14 Issue: 2 Pages: 191-196
Publisher: Al-Nahrain University جامعة النهرين

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Abstract

Background: Hyponatremia is a common electrolyte disorder encountered in patients of stroke, which is usually either due to inappropriate secretion of antidiuretic hormone (SIADH) or cerebral salt wasting syndrome (CSWS). Making an accurate diagnosis is important because the treatment of each condition is quite different. Objectives:We conducted this study to determine the incidence and etiology of hyponatremia in patients of stroke.Methods:A cross sectional study of 100 patients diagnosed to have stroke (50 ischemic, 50 hemorrhagic) based on clinical history, examination and brain images. Patients were evaluated for hyponatremia (serum sodium < 135 mmol/L) during the second week of their admission. Results:Out of 100 patients, 17 patients had hyponatremia, all Patients with serum sodium level in hyponatremic range were limited to patients with hemorrhagic stroke, while no patients with ischemic stroke had a low serum sodium level, this difference was significantly different, P-value was < 0.001.Conclusion:Incidence of hyponatremia in our study population was 17%, all Patients with hyponatremia were limited to patients with hemorrhagic stroke, in patients of hyponatremia; 82% were having SIADH and 18% were having CSWS.Keywords: Hyponatremia, ischemic stroke, hemorrhagic stroke, syndrome of inappropriate antidiuretic hormone, cerebral salt wasting syndrome.


Article
SERUM HDL IN PATIENTS WITH ISCHEMIC STROKE - A CASE CONTROL STUDY

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Abstract

Background:Elevated high-density lipoprotein cholesterol (HDL-C) levels have been shown to be protective against cardiovascular disease. However, the association of specific lipoprotein classes and ischemic stroke has not been well defined.Objectives:To evaluate the association between HDL-C and ischemic stroke in men and women, and to compare the results with a control sample of the same age group.Methods:A hospital based case-control study was done comparing serum HDL-C levels in 48 ischemic stroke patients to 50 controls recruited from Al-Imamain Al-Kadhemain Medical City, all patients and control had negative past medical history, negative history for smoking and alcohol. Serum lipid profile was determined in all of them.Results :This study showed that regarding the serum HDL-C levels, 41 (85.4%) patients were found to have low levels (less than 40 mg/dl) while among the control group, only 19 (38%) have shown low serum HDL-C level.Conclusion:The study showed that there is a significant association between the low level of serum HDL-C cholesterol and the risk of ischemic stroke in this population.Keywords: cholesterol, lipoproteins, HDL-cholesterol, ischemic stroke

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