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Article
Perniosis: Clinical and Epidemiological Study in Iraqi Patients

Author: Adil A. Al-Nuaimy
Journal: Iraqi Academic Scientific Journal المجلة العراقية للاختصاصات الطبية ISSN: 16088360 Year: 2009 Volume: 8 Issue: 1 Pages: 11-13
Publisher: The Iraqi Borad for Medical Specialization المجلس العراقي للاختصاصات الطبية

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Abstract

ABSTRACT:BACKGROUND:Perniosis(chilblains) is a common skin problem. This condition results from abnormal reaction to cold which is usually seen during the cold months of year.OBJECTIVE:The aim of the present study is to shed a light on different clinical and epidemiological aspects of perniosis in Iraq.METHODS:A total of 40 patients with perniosis were seen between January to march 2008 in the department of dermatology and venereology of Baghdad Teaching Hospital.A detailed history was taken from each patient regarding age, sex, occupation, duration of attack, family history, smoking, drug history, medical history, relieving and aggrevating factors and previous treatment modality.Full examination was done to each patient to assess the distribution and extent and morphology of the lesions and to see if there other skin diseases. Biopsies was done for 6 patients for histopathological study.RESULTS:A total of 40 patients were assessed. Their ages ranged from 5-60 years with a mean age of 22 SD± 6.2, 31 females and 9 males (3.5:1).Main sites of involvemnt were; toes 39% , fingers 22% ,heals 10% and nose 2.5% .Main types of lesions were ; erythematous cyanotic swellings 82% , vesicular lesions 23% ,ulcerations 10% and erythema multiforme like lesions 15%. Family history was positive in 22.5% of patients.CONCLUSION:Perniosis occur mainly in females between 10-20 years . Most common sites of involvement are toes and fingers . genetic susceptibility is an important factor in the development of the disease. Majority of patients are healthy without any medical or dermatological diseases .Majority are non smokers and did not have any history of drug intake.


Article
Dermatofibrosarcoma Protuberans: "Epidemiological and Clinical Study"
الورم الجلدي الليفي الضام الناتئ الخبيث (دراسة وبائية –سريرية)

Author: Adil A. Al-Nuaimy د. عادل عبد الغفور النعيمي
Journal: IRAQI JOURNALOF COMMUNITY MEDICINE المجلة العراقية لطب المجتمع ISSN: 16845382 Year: 2008 Volume: 21 Issue: 4 Pages: 335-338
Publisher: Al-Mustansyriah University الجامعة المستنصرية

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Abstract

Background: Dermatofibrosarcoma protuberans is a locally aggressive invasive dermal and subcutaneous mesenchymal neoplasm. Males are affected more often than females. It typically occurs during the third and fourth decades of life.Objective: To determine the clinical, histopathogical and epidemiological aspects of dermatofibrosarcoma protuberans in Iraqi patients.Patients &Methods: This case series study was carried out in the Department of Dermatology & Venereology-Baghdad Teaching Hospital during the period from June 2000 to December 2006.Twenty patients with dermatofibrosarcoma protuberans were included in this work. Socio-demographic information, full clinical, dermatological examination and biopsy were done for each patient. Results: Twenty patients were involved in the present work, all showed typical clinical features of the disease. Their ages ranged from 7-75 (mean ± SD) (38.55 ± 21.33) years, while the duration of the disease ranged from 3-24 (mean ± SD) (23.28 ±10.53) months. There were 14(70%) males and 6(30%) females with a male to female ratio 2.3:1. The geographical distributions of these cases were: 9(45%) cases from South of Iraq, 11(55%) patients from Baghdad.The main sites involved were the extremities 10(50%) and 5(25%) for each one of the trunk and head. The clinical features of the diseases were not much different from what have been published in medical literatures .Histopathological study of lesions revealed the typical histological features of dermatofibrosarcoma protuberans in all cases. Conclusion: The present study confirmed that dermatofibrosarcoma protuberans is disease of male and it is the first report from Iraq recording cases from Middle and South regions only. Keywords: dermatofibrosarcoma protuberans, malignancy, clinical, epidemiological.

أساس البحث: الورم الجلدي الليفي الضام الناتئ الخبيث من الأورام الخبيثة الشديدة الاختراق الموضعي للأدمة والطبقة الدهنية للجلد.الذكور هم أكثر عرضة للإصابة بهذا الورم من الإناث.يحدث عادة في العقدين الثالث والرابع من العمر. هدف البحث: لتسليط الضوء على النواحي الوبائية السريرية والنسيجية للورم الجلدي الليفي الضام الناتئ الخبيث في المرضى العراقيين والذي لم يذكر سابقا في العراق. المرضى وطرائق البحث:هذه الدراسة(دراسة سلسلة حالات)أجريت في قسم الأمراض الجلدية والتناسلية في مستشفى بغداد التعليمي خلال الفترة من حزيران 2000لغاية كانون الاول2006.كان عدد المرضى المصابون بالورم الجلدي الليفي الضام الناتئ الخبيث في هذه الدراسة هوعشرون.جميع النواحي الاجتماعية والمعلومات السريرية والجلدية قد اخذت من كل مريض بالتفصيل وكل ما له صلة بالمرض.تم اخذ خزعة من كل مريض للتثبت من التشخيص.النتائج: عشرون مريضا تم فحصهم في هذا العمل واظهروا اكل الاعراض السيريه المثالية لورم الجلدي الليفي الضام الناتئ الخبيث.تراوحت اعمارهم بين7-75 سنة مع متوسط العمر وانحراف معياري 21,33سنه,.بينما ترواحت فترة المرض بين 3-24 شهر ±38,55 مع متوسط العمر وانحراف معياري 10,53 ±23,28شهر.اربعة عشر(70%) منهم من الذكور وستة(30%)من الاناث ونسبه الذكور للاناث هي 2,3:1.التوزيع الجغرافي للمرضى كان كالاتي:9(45%)حاله من جنوب العراق,11(55%) مريض من بغداد. كانت الاطراف الموضع الرئيسي في 10(50%) مرضى وفي خمس(25%) حالات لكل من الجذع والراس.الاعراض السريريه للمرض لم تختلف كثيرا عما منشور ومثبت في الادب الطبي.الفحص النسيجي للورم اظهرالصفات والعلامات المثالية والنموذجية للمرض في جميع الحالات.الاستنتاج: تم الاستنتاج من الدراسة المقدمة الورم الجلدي الليفي الضام الناتئ الخبيث هو مرض الذكور.وهذه اول دراسة تسجلهذا الورم من وسط وجنوب العراق فقط.


Article
The Effectiveness & Safety of Topical Podophyllin Therapy in Condylomata Acuminata in Iraqi Infants and Young Children
ألثآليل ألجنسية لدى ألرضع وألأطفال العراقيين (محلول البودوفيلين الموضعي كعلاج فعال)

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Abstract

AbstractBackground: Condylomata acuminata an infection caused by Human papilloma virus. The incidence of anogenital warts among children is rising. Still anogenital warts can be the only manifestation of child sexual abuse. Human papilloma virus typing dose not provide definitive evidence for or against sexual abuse.Objective: To evaluate this condition among Iraqi children and to report the experience with podophyllin.Method: Condylomata acuminata was studied in eighteen infants and young children, attending the Department of Dermatology & Venereology- Baghdad Teaching Hospital in Period from January 1996 to January 2000.Results: The ages of patients ranged from 6 – 84 months (mean ± SD23.66 ± 20.30 months), 11 females and 7 males. The duration of the disease ranged from 3 – 8 months (5.83 ± 1.24 months). The clinical pictures were mostly a cauliflower like warts affecting the genital area, anal and perianal areas. Sexual abuse was not confirmed in any case. Family history of genital warts was denied among all family members apart from one girl that her mother had verruca vulgaris on their fingers. Fifteen percent Podophyllin in tincture benzoin was an effective therapy and all lesions had disappeared after 1 – 3 applications (1.77 ± 0.73 months) once weekly with no sign of relapse through several months of follow up.Conclusion: The present work is compatible with the increase in the frequency of genital warts among infants and young children all over the world. Since there was no history of sexual abuse in affected patients, we believe that genital warts result from direct contact with other members of the family, who are either not aware of the presence of warts or they have latent infection. Podophyllin seems to be the drug of choice for all patients who responded quickly to this mode of therapy. This experience with podophyllin in this age group has not been reported in the published literatures.Key Words: Condylomata acuminata, infants & young children, Podophyllin

الملخص ألهدف:تقييم الثاّليل الجنسية عند الرضع والاطفال العراقيين وتسجيل البودوفيلين كطريقة لعلاج الثاّليل الجنسية عند الاطفال.ألطريقة:تمت دراسة الثاّليل الجنسية في ثمانية عشر من الاطفال الرضع تراوحت اعمارهم بين 0.6-7 سنوات مع معدل الاعمار 1.7±0.6سنة كان المرضى يتكونون من عشر اناث وسبع ذكور. وقد تم اخذ تاريخ المرض من اباء المرضى وفحصهم سريريا. تم استخدام البودوفلين 15% بمعدل استعمال واحد في الاسبوع وقد تمت المتابعة خلال عدة اشهر.ألنتائج:سريريا كان المرضى يعانون من ثاّليل على شكل زهرة القرنابيط (Cauliflower Like) في المناطق التناسلية الشرجية وحول الشرجية. لم يتأكد ألأستغلال الجنسي في اي حالة. ولم يكن هناك اي تاريخ مرضي لحالة مشابهة في عوائل المرضى .تم استعمال محلول البودوفلين 15% موضعيا وكان علاجا فعالا اختفت جميع الاّفات بعد 1-3 استعمالات . لم تكن هناك اي حالة ارتجاع بعد عدة اشهر من المتابعة.خاتمة: جاءت هذه الدراسة متوافقة مع زيادة الاصابة بالثاّليل الجنسية بين الرضع والاطفال في العالم. لم يتأكد الأستغلال الجنسي في اي حالة, لذلك نعتقد ان الثاّليل الجنسية جاءت من التلامس مع افراد عوائلهم, الذين لم يكترثوا لوجود الثاّليل او الاصابة المستترة.يبدو البودوفلين كعلاج فعال لكل المرضى الذين استجابوا بسرعة لهذا العلاج. هذه التجربة مع البودوفلين في هذا العمر من المرضى لم تسجل سابقا في الدوريات المنشورة.


Article
Treatment of Pityriasis Versicolour with Topical 15% Zinc Sulfate Solution
علاج داء النخالة المبرقشة بمحلول كبريتات الزنك الموضعي

Authors: Khalifa E. Sharquie د.خليفة الشرقي --- Wisam S. Al- Dori وسام الدوري --- Inas K. Sharquie د. ايناس الشرقي --- Adil A. Al– Nuaimy
Journal: IRAQI JOURNALOF COMMUNITY MEDICINE المجلة العراقية لطب المجتمع ISSN: 16845382 Year: 2008 Volume: 21 Issue: 1 Pages: 61-63
Publisher: Al-Mustansyriah University الجامعة المستنصرية

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AbstractBackground: Pityriasis versicolour is a common skin problem of cosmetic importance among young individuals. Many modality of the treatment have been used to control this disease, but often end with relapse. Zinc sulfate had been proven to have antifungal activity invitro study. Still we are searching for a new therapeutic agent like zinc sulfate.Objective: The aim of the present work is to assess the therapeutic effectiveness of topical 15% zinc sulfate solution in treatment of tinea versicolor.Patients& Methods: This single blinded controlled therapeutic trail was carried out in Department of Dermatology and Venereology - Baghdad Teaching Hospital, during the period from May 2004- Sept. 2004. Patients consisted of 60 person (40 males&20 females) and their ages ranged from 15 – 45 years with a mean ± SD of 32 ± 3 years, while the duration of the disease was 2-30 ( 5.18 ± 4.77) months. These patients were enrolled in this study and were divided into two groups:-Group A: Thirty patients (16 males and 14 females) were treated with topical 15% zinc sulfate solution once daily and examine every week for three weeks and followed up for one month without therapy. Mycological and Wood's light examination were performed to establish diagnosis before therapy and repeated every week to asses the response to therapy.Group B: Thirty patients (24 males and 6 females) were treated with distilled water as a placebo treated group and with a similar manner in group A.Results: The result of this study revealed that all patients in group A showed clinical and mycological clearance at the end of 3rd week of treatment while group B showed no clinical and mycological recovery at the end 3rd week of treatment program. No side effects were recorded apart from mild itching in few patients during the first days of therapy.Conclusion: Topical 15% zinc sulfate solution is an effective, new, mode of therapy which is simple, non costly treatment option for pityriasis versicolour with negligible side effects. Keyword: pityriasisr versicolour, topical zinc sulfate solution.

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