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Article
INTERFERON ALPHA-2B IN PLANTAR FASCIITIS
التهاب اللفافة الاخمصي

Author: Adnan A.Anoze عدنان عبد عنوز
Journal: IRAQI JOURNAL OF MEDICAL SCIENCES المجلة العراقية للعلوم الطبية ISSN: P16816579,E22244719 Year: 2008 Volume: 6 Issue: 1 Pages: 128-131
Publisher: Al-Nahrain University جامعة النهرين

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Abstract

Background: Plantar fasciitis is the most common cause of heel pain but treatment remains empirical.Objective: To investigate the effect of interferon alpha 2b on pain, morning stiffness and tenderness of heels in patient with plantar fasciitis.Methods: Three hundred seventy six patients with plantar fasciitis enrolled in this study. The patients divided into two groups: Group one received interferon alpha 2b 3MIUevery 3 days and group two treated with diclofenac. 50 mg two times daily with heel pads. The study conducted for 12 week. Results: 92% of group one patients who received interferon alpha 2b became completely asymptomatic at week 6. At week 12 96.8% became completely free of symptoms.Conclusion: Treatment with interferon alpha 2b in patients who had plantar fasciitis seems to be effective bringing complete cure.

خلفية الدراسة: التهاب لفافة أخمص القدم من أكثر أسباب الآم كعب القدم ولكن العلاج بقي غير وافي وتجريبي.هدف الدراسة: لغرض فحص تأثير وفائدة العقار انترفيرون الفاتوبي على الآم كعب القدم وتيبس القدم الصباحي لدى مرضى التهاب لفافة اخمص القدم.طريقة العمل: 376 مريضاً يعانون من التهاب لفافة أخمص القدم ادخلوا في هذه الدراسة تم تقسيم المرضى إلى مجموعتين المجموعة الأولى تناولت انترفيرون الفاتوبي ثلاثة ملايين وحدة كل ثلاثة أيام والمجموعة الثانية تناولت دايكلوفيناك 50 ملغم مرتين في اليوم مع استعمال وسادة للكعب الدراسة استمرت لمدة 12 أسبوع .النتائــج: 92% من المجموعة الأولى التي تناولت انترفيرون الفاتوبي اظهروا تحسناً ملموساً وقد اختفت كافة أعراض المرض بعد مرور 6 أسابيع في نهاية الأسبوع الثاني عشر 96.8% من مرضى المجموعة الأولى بدون أعراض مرضية.الاستنتاجات: علاج مرضى التهاب لفافة أخمص القدم بعقار انترفيرون الفاتوبي اظهر جدوى وفعالية عالية في شفاء المرضى واختفاء أعراض المرض.


Article
EDITORIAL: SAFETY OF HEALTH CARE

Author: Adnan A. Anoze عدنان عبد خشان عنوز
Journal: IRAQI JOURNAL OF MEDICAL SCIENCES المجلة العراقية للعلوم الطبية ISSN: P16816579,E22244719 Year: 2010 Volume: 8 Issue: 1 Pages: 1-1
Publisher: Al-Nahrain University جامعة النهرين

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Article
Antihyperlipidemic Effect of L-Thyroxine Combined with Carvedilol in Induced Hyperlipidemia in Rabbits

Authors: Muayyad Sraibit Abbod --- Faruk H. Al-Jawad --- Adnan A. Anoze --- Mufeda Ali Jawad
Journal: Medical Journal of Babylon مجلة بابل الطبية ISSN: 1812156X 23126760 Year: 2014 Volume: 11 Issue: 4 Pages: 1047-1059
Publisher: Babylon University جامعة بابل

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Abstract

Background:Hyperlipidemia is defined as an elevation of one or more of the plasma lipids, including cholesterol, cholesterol esters, triglycerides (TG) and phospholipids .An elevation of plasma lipids may be caused by primary or secondary factors.Objective:To evaluate the effect of L-thyroxine - Carvedilol combination on hyperlipidemia induced in rabbits. Material and method:Forty healthy, domestic rabbits of both sexes, weighing (800 – 1100 grams) were used in this study. They were divided into five groups each one contains eight rabbits. The first group (G1) was given a standard diet to be considered as a control group while all other groups fed with high cholesterol diet. The second group (G2) was given high cholesterol diet only, third group (G3) treated with atorvastatin , (G4) treated with L-thyroxine and (G5) received L-thyroxine combined with carvedilol. Then lipid profile, heart rate and body weight were measured for all groups to be compared. Results:Because atorvastatin is a known antihyperlipidemic drug, the results of using combination of L-thyroxin with carvedilol were compared to those produced by atorvastatin alone. The results showed insignificant (p˂0.05) difference in all biochemical parameters, heart rate and body weight of the hyperlipidemic group treated with the combination of L- thyroxin and carvedilol (G5) when compared with those treated with atorvastatin alone (G3). Conclusion:The use of the combination of L-thyroxine and carvedilol has antihyperlipidemic effect similar to that of atorvastatin which is well known antihyperlipidemic drug.

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