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The Correlation Between Total White Blood Cell Count, Total Lymphocyte Count, & the CD4+ T-helper Lymphocyte Count among Iraqi HIV Infected Patients

Authors: Kamal-Udeen M. Fatah --- Arwa H. Al-Hamdani --- Adnan H. Jawad
Journal: Mustansiriya Medical Journal مجلة المستنصرية الطبية ISSN: 20701128 22274081 Year: 2008 Volume: 7 Issue: 1 Pages: 41-44
Publisher: Al-Mustansyriah University الجامعة المستنصرية

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Abstract

Study of the correlation between changes in the white blood cell count WBC), total lymphocyte count (TLC) and the CD4+ T-helper lymphocyte count (CD4), have been carried out during Oct. 2004 through April. 2005 among 35 HIV seropositive Iraqi patients and 30 seronegative individuals. ELISA and Western blot assays were used to detect and confirm the presence of anti- HIV antibodies in the blood samples.Patients and control groups have been classified into (4) categories according to the obtained results of CD4 count: 200, 200-500, 500-1000, and >1000 cell/cmm. This categorization shows that: none of the HIV seropositives was found to be within the first category; six within the second category (mean CD4 = 383.2 cell/cmm, SD= 92.6) twenty-one within the third category (mean CD4 = 787.9 cell/cmm, SD= 131.6); and eight within the fourth category (mean CD4= 1237.1 cell/cmm, SD= 159.4). While among the control group: none of them was found to be within the first category; only one within the second category (CD4= 464 cell/cmm); twenty-six within the third category (mean CD4 = 745.7 cell/cmm, SD= 116.2); and three within the fourth category (mean CD4= 1333 cell/ cmm, SD= 331).Results showed that among HIV seropositives a strong significant, positive correlation was found between changes in CD4 and TLC within the second and the third categories, and even when the whole data uncategorized) were used. While there was a moderate significant positive correlation within the fourth category. The correlation between total WBC and CD4 was found to be insignificant.

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Article
IMMUNOLOGICAL DIAGNOSIS OF CELIAC DISEASE IN SYMPTOMATIC CHILDREN IN KIRKUK GOVERNORATE
التشخيص المناعي من حساسية الحنطة (الداء الزلاقي) في أطفال لديهم أعراض في محافظة كركوك

Authors: Adnan H. Jawad عدنان هادي جواد --- Farhan A. Risan فرحان عبود رسن --- Braihan H. Hameed بريهان حمدي حميد
Journal: AL-TAQANI مجلة التقني ISSN: 1818653X Year: 2014 Volume: 27 Issue: 2 Pages: E32-E38
Publisher: Foundation of technical education هيئة التعليم التقني

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Abstract

The aim of the present study is to estimate the occurrence of the celiac diseaseamong clinically suspected children using immunoglobulin antibodies against gliadin(IgA and IgG-AGA) and against human tissue transglutaminase (IgA and IgG-tTG) asscreening method. The study included 60 children with signs and symptoms suggested tohave celiac disease (average age 36 months) who attended the Children's Hospital/Kirkuk during the period from November/ 2011 until March/ 2012 and 30 apparentlyhealthy children (average age 45 months) were chosen as a control group. Negativeresults were obtained in 33 (55.0%) clinically suspected children and 30 (100%) ofcontrol children. Positive results included antigliadin antibodies (IgA-AGA and IgGAGAor both) in 27 (45.0%) patients and tissue transglutaminase (IgA-tTG and IgGtTGor both) in 10 (16.6%) patients. The biopsy of five children were positive for bothAGA (IgA and IgG) and tTG (IgA and IgG) revealed that characteristic lesions of celiacdisease. It can be concluded that among the 60 patients that were tested, positive resultsof AGA (IgA and IgG) and tTG (IgA and IgG) represented (13.3%) and (11.7%)respectively and (8.3%) were confirmed by biopsy.

الهدف من الدراسة الحالية هو تقدير حدوث مرض حساسية الحنطة بين اطفال مشتبه بإصابتهم سريرياً بالمرض باستخدام الأضداد المناعية ضد غليادين (الكلوبيولينات المناعية A و G) وضد ترانسكلوتامنيز (الكلوبيولينات المناعية A و G) كطريقة مسحية. شملت الدراسة 60 طفلا لديهم علامات وأعراض توحي اصابتهم بالمرض (متوسط العمر 36 شهرا) الذين حضروا مستشفى الأطفال/ كركوك خلال الفترة من تشرين الثاني 2011/ ولغاية اذار/2012 وتم اختيار 30 طفلا أصحاء (متوسط العمر 45 شهرا) كمجموعة سيطرة. تم الحصول على نتائج سلبية في 33 (55.0%) من اطفال مشتبه بإصابتهم سريريا و30 (100%) من الأطفال السيطرة. شملت النتائج الايجابية أضداد الغليادين (الكلوبيولينات المناعيةA و Gاو كليهما معا) في 27 (45.0%) مريضا وأضداد الترانسكلوتامنيز (الكلوبيولينات المناعية A و Gاو كليهما معا) في 10 (16.6%) مرضى. كشفت الخزعات لخمسة أطفال ايجابية لكلا أضداد الغليادين (الكلوبيولينات المناعيةA وG ) وأضداد الترانسكلوتامنيز (الكلوبيولينات المناعية A و G) أن هناك تقرحات مميزة لمرض حساسية الحنطة. يمكن الاستنتاج أن من بين 60 مريضا التي تم فحصهم, نتائج ايجابية من أضداد الغليادين (الكلوبيولينات المناعيةA و (G وأضداد الترانسكلوتامنيز (الكلوبيولينات المناعية A و G) مثلت ((13.3% و (11.7%)على التوالي وتم تاكيد(8.3%) بواسطة الخزعة.

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