research centers


Search results: Found 5

Listing 1 - 5 of 5
Sort by

Article
A Spectroscopic Study on the Level Of Serum Selenium in Northern Baghdad Subject

Author: Ahsan.K.Abbas
Journal: Iraqi Academic Scientific Journal المجلة العراقية للاختصاصات الطبية ISSN: 16088360 Year: 2006 Volume: 5 Issue: 3 Pages: 351-352
Publisher: The Iraqi Borad for Medical Specialization المجلس العراقي للاختصاصات الطبية

Loading...
Loading...
Abstract

ABSTRACT:BACKGROUND:This work is performed to measure the concentration of serum selenium in northern Baghdad subject. Selenium is one of the trace element that plays an important role in physiological functions of human body.MATERIALS AND METHODS:Selenium levels of blood serum were measured using furnace atomic absorption spectrophotometer.RESULTS :The results obtained in this work showed a decrease in selenium level and the reduction is proportional to the duration of age. This can be explained principally due to the type of diet and malabsorption young subject may differ in certain diet intake.

Keywords

selenium --- spectroscopy.


Article
Enzyme linked immunosorbent assay (ELSA) investigation for Human Kisspeptin and progesterone Levels in female having regular menstrual cycle

Author: Ahsan K. Abbas احسان كاظم عباس
Journal: Journal of the Faculty of Medicine مجلة كلية الطب ISSN: 00419419 Year: 2011 Volume: 53 Issue: 2 Pages: 211-215
Publisher: Baghdad University جامعة بغداد

Loading...
Loading...
Abstract

Background: Kisspeptin the product of the gene Kiss1 is a G-protein coupled receptor legend for GPR54. Kiss1 was originally identified as a human metastasis suppressor gene that has the ability to suppress melanoma and breast cancer metastasis. It is recently become clear that kisspeptin-GPR54 signaling has an important role in initiating GnRH secretion at puberty, the extent of which is an area of ongoing research.
Objective: The present study was designed to determine the change of plasma kisspeptin levels during the menstrual cycle
Materials & Methods: A total of 20 women from friends and relatives pool were involved in this study. Selected from frinds and relative .They were selected after measuring their progesterone level on day 21 of menstrual cycle (excluding women who have anovulate menstrual cycle; low level of progesterone) , and then on 1 -5 day of the next menstrual cycle. All measurements were done in Teaching laboratories in Baghdad Teaching Hospital in Baghdad/Iraq. Five mls of blood withdrawn from each selected women by veinpuncture of selected women. ELISA technique was used for the measurement of serum kisspeptin -1and progesterone level. Data were expressed as a mean ±SD. Results were evaluated using the student t-test for paired data. Conventional methods were used for the correlation and regression analyses.
Results: Results obtained showed that the levels of serum kisspeptin and progesterone were significantly higher on day 21of menstrual cycle than during menstruation period with p<0.01, also it was found a significant positive correlation of kisspeptin level with progesterone level (r= 0.77 ,p<0.01).
Conclusion: The results determine the role of kisspeptin on ovulation, and give a possibility for its beneficial manipulation of human fertility.


Article
Serum and Erythrocyte Magnesium Levels in Patients with Myocardial Infarction with or without Heart Failure

Authors: Laith S. Abdul-Al Haliim Al-Naqib --- Ahsan K. Abbas --- Basil N. Saeed*
Journal: Iraqi Academic Scientific Journal المجلة العراقية للاختصاصات الطبية ISSN: 16088360 Year: 2013 Volume: 12 Issue: 3 Pages: 372-375
Publisher: The Iraqi Borad for Medical Specialization المجلس العراقي للاختصاصات الطبية

Loading...
Loading...
Abstract

BACKGROUND :Magnesium (( Mg(1) )) is a mineral that is involved in over 300 reactions in the body. Magnesium is aPotent vasodilation ,and plays an important role in muscle contraction. It has been earlydocumented that Mg deficiency can precipitate ventricular arrhythmias and treatment with Mg hassome anti arrythmic effect. Moreover there is an ample evidence that a significant percentage ofpatients with IHD suffer from Mg. The risk of IHD increaseswith age, smoking, hypercholesterolaemia,diabetes mellitus, hypertension(1). Ischemic heartdisease presented as stable angina , unstableangina , myocardial infarction , ischemic heartfailure and ischemic cardiomyopathy. Thediagnosis of ischemic heart disease depend onclinical history and investigation including: *Ministry of Health AL-Bitar Hospital,Baghdad.Iraq.**Biochemistry Dept. Collage of Medicine University of Baghdad.*** Dept. Baghdad Medicine City. deficiency.OBJECTIVE : The objective of the present study is to measure Mg(2) levels in serum and RBCs of patients withsome forms of IHD. PATIENTS AND METHODS:The study was conducted in Baghdad hospital and Ibn – Al-Bitar Hospital.The 180 patients withIHD were divided into Two groups. Group I, 80 patients with Ischemic Heart Failure (IHF)(EF˂30) aged 65.75±5.97 year (50 males and 30 females), group II, 100 patients withMuocardial Infarction (MI)(EF˂50) aged 50.34±6.36 year (58 males and 42 females). Serum Mg and RBCs Mg weremeasured in all patient groups by Atomic Absorption Spectrophotometer.RESULTS: The(mean ±SD) value of serum and RBCs Mg in patients with both groups Ischemic Heart Disease(IHD) was significantly lower when compared with that of controls (p<0.05).The serum Mg levels (0.81±SD mmol/L) are significantly lower in the IHF group and in MI group (0.96±0.18 mmol/L)when compared with that of controls (1.00±0.17 mmol/L) (p˂ 0.001).CONCLUSION: The data obtained in present study revealed the decrease of Mg level in serum and RBCs in bothpatients groups, which affect the contractility of heart muscle and cardiac performance


Article
The Relationship between Reproductive Hormones and Metabolic Parameters in Women with Polycystic Ovary Syndrome
العلاقة بين الهرمونات التكاثرية والمتغيرات الأيضية لدى النساء المصابات بمتلازمة تكيس المبايض

Authors: Ahsan K. Abbas احسان خليل عباس --- Hind Sh. Ahmed هند شاكر احمد
Journal: Journal of the Faculty of Medicine مجلة كلية الطب ISSN: 00419419 Year: 2014 Volume: 56 Issue: 2 Pages: 234-238
Publisher: Baghdad University جامعة بغداد

Loading...
Loading...
Abstract

Background: Polycystic ovarian syndrome (PCOS) is a condition associated with chronic anovulation, and androgen excess. Clinically, PCOS women usually presents with menstrual irregularities, infertility, and hirsutism. Women with this syndrome are at increased risk of metabolic syndrome (MS). Objective: To study the characteristics of the MS in women with PCOS.Patients and Methods: This study was conducted during the period from March 2013 until the end of September 2013. A total of 50 PCOS women were studied (25 PCOS women with MS and 25 PCOS women without MS) with an age ranged from (35-45) years. Women with PCOS were referred to Medical City Hospital in Baghdad and compared with 25 healthy women as control group. Serum luteinizing hormone (LH), follicle stimulating hormone (FSH), prolactin, progesterone, testosterone, fasting serum glucose (FSG), serum triacylglycerol (TAG), and high density lipoprotein cholesterol (HDL-C) were measured for each individuals. Results: Means of FSG, TAG, LH, prolactin, progesterone, testosterone levels, and LH/FSH ratio were significantly elevated in PCOS women than in the control group, while serum HDL-C levels were significantly lowered in PCOS women than in the control. There was a significant increase in FSG and TAG in PCOS women with MS as compared to PCOS women without MS, (P=0.0001). While, there was a significant decrease in serum HDL-C in PCOS women with MS as compared to PCOS women without MS. No significant differences were found in LH, FSH, prolactin, progesterone, testosterone, LH/FSH ratio, day of menstrual cycle, and duration of infertility between PCOS women with and without MS. Conclusions: The present study showed that PCOS women with MS had abnormalities in hormonal and lipid profile. Key Words: Polycystic ovarian syndrome, metabolic syndrome, hormonal profile.

خلفية البحث: تعد متلازمة تكيس المبايض حالة مرضية مرتبطة بعدم الأباضة وزيادة الأندروجينات. تعاني مريضة تكيس المبايض سريرياً من عدم انتظام الدورة الشهرية، العقم، وظهور الشعر. والنساء اللاتي تعاني من هذه الأعراض تكون أكثر عرضة للأصابة بالمتلازمة الأيضية.الهدف من الدراسة: دراسة مظاهر المتلازمة الأيضية لدى النساء المصابات بتكيس المبايض.المرضى وطرق العمل: أجريت هذه الدراسة خلال الفترة من اذار 2013 حتى نهاية ايلول 2013. تمت دراسة 50 امرأة مصابة بتكيس المبايض )25 امرأة مصابة بتكيس المبايض وتعاني من المتلازمة الأيضية و 25 امرأة مصابة بتكيس المبايض ولا تعاني من المتلازمة الأيضية) بمعدل عمر تراوح بين (35-45) سنة. تمت إحالة النساء المصابات بتكيس المبايض إلى مستشفى مدينة الطب في بغداد ومقارنتهم مع 25 امرأة سليمة كمجموعة سيطرة. تم قياس الهرمون اللوتيني، الهرمون المحفز للجريبات، هرمون الحليب، البروجستيرون، التيستوستيرون، نسبة السكر في الدم، الدهون الثلاثية، والبروتين الدهني عالي الكثافة لدى جميع الأفراد.النتائج: كانت مستويات السكر في الدم، الدهون الثلاثية، الهرمون اللوتيني، هرمون الحليب، البروجستيرون، مستويات هرمون التيستوستيرون، ونسبة الهرمون اللوتيني/الهرمون المحفز للجريبات مرتفعة معنوياً لدى النساء المصابات بتكيس المبايض بالمقارنة مع مجموعة السيطرة، في حين كانت مستويات البروتين الدهني عالي الكثافة أقل بكثير لدى النساء المصابات بمتلازمة تكيس المبايض بالمقارنة مع مجموعة السيطرة. هنالك زيادة معنوية في سكر الدم والدهون الثلاثية لدى النساء المصابات بتكيس المبايض ويعانين من المتلازمة الأيضية بالمقارنة مع النساء المصابات بتكيس المبايض ولا يعانين من المتلازمة الأيضية، (P=0.0001). بينما هنالك انخفاض معنوي في البروتين الدهني عالي الكثافة لدى النساء المصابات بتكيس المبايض ويعانين من المتلازمة الأيضية بالمقارنة مع النساء المصابات بتكيس المبايض ولا يعانين من المتلازمة الأيضية. لا يوجد فرق معنوي في الهرمون اللوتيني، الهرمون المحفز للجريبات، هرمون الحليب، البروجستيرون، التيستوستيرون، نسبة الهرمون اللوتيني/الهرمون المحفز للجريبات، يوم الدورة الشهرية، وفترة العقم بين النساء المصابات بمتلازمة تكيس المبايض مع وبدون المتلازمة الأيضية.الأستنتاجات: تظهر الدراسة الحالية بأن النساء المصابات بتكيس المبايض ويعانين من المتلازمة الأيضية لديهن خلل في صورة الهرمونات والدهون في الدم.كلمات مفتاحية: متلازمة تكيس المبايض، المتلازمة الأيضية، صورة الهرمونات.


Article
Status of Some Minerals in Patients with Polycythemia using Colorimetric Method

Authors: Ahsan K. Abbas احسان عباس --- Mohammed S. Al-Sayab محمد صالح --- Mayssa J. Majeed ميساء جاسم ماجد
Journal: Journal of the Faculty of Medicine مجلة كلية الطب ISSN: 00419419 Year: 2010 Volume: 52 Issue: 1 Pages: 98-100
Publisher: Baghdad University جامعة بغداد

Loading...
Loading...
Abstract

Background: Polycythemia (or polycythaemia or erythrocytosis) is a condition in which there is a net increase in the total number of blood cells, primarily red blood cells, in the body. The overproduction of red blood cells may be due to a primary process in the bone marrow (a so-called myeloproliferative syndrome), or it may be a reaction to chronically low oxygen levels or, rarely, a malignancy. Minerals are the building blocks of our bodies. They are required for body structure, fluid balance, protein structures and to produce hormones. They are the key for the health of every body system and function. They act as co-factors, catalysts or inhibitors of all enzymes in the body . Patients and Methods: Blood Calcium, iron & Magnesium concentrations was determined by using colorimetric method, while Potassium, Copper& Zinc concentration was determined by using flam atomic absorption spectrometry method.Results: Obtained results showed that the level of Potassium, Calcium and zinc in polycythemic subjects were significantly higher than that of healthy subjects (p<0.05), while serum iron, Copper in polycythemic subjects were significantly lower than that of healthy subjects. Magnesium level shows no significant difference between two studied groups.Conclusion: Recent research indicates that minerals may play a significant role against a variety of degenerative diseases and processes.Keywords: Polycythemia, Minerals, Sialic acid, calcium, iron, potassium, Copper, Zinc.

Keywords

Polycythemia --- Minerals --- Sialic acid --- calcium --- iron --- potassium --- Copper --- Zinc.

Listing 1 - 5 of 5
Sort by
Narrow your search

Resource type

article (5)


Language

English (5)


Year
From To Submit

2014 (1)

2013 (1)

2011 (1)

2010 (1)

2006 (1)