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The Role of Omega-3 EPA/DHA Oral Soft gel in The Treatment of Stable Bronchiectasis

Author: Ali Salih Baay
Journal: Medical Journal of Babylon مجلة بابل الطبية ISSN: 1812156X 23126760 Year: 2016 Volume: 13 Issue: 4 Pages: 818 -825
Publisher: Babylon University جامعة بابل

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Abstract

The omega 3 has a known anti-inflammatory effect which can be beneficial in many human diseases in the respiratory & other systems. In respiratory system its role is not mature yet as in asthma, COPD & bronchiectasis & most are still under study.The safety issues also need to be addressed in the treatment with a relatively need medication.To evaluate the use of omega-3 EPA/DHA oral softgel in the treatment of stable (not in exacerbation) bronchiectasis regarding safety/efficacy effect.44 Patients with stable bronchiectasis are randomly assigned to the active group (participants receive omega-3 EPA/DHA oral softgel (EPA 180mg &DHA 120mg ) once daily for 6 months in addition to their usual treatment) or the control group (participants receive the usual treatment only for 4 months) from January 2013 to march 2016.Interventional randomized parallel assignment study concern in the safety /efficacy of a suggested treatment.Omega 3 can used in patients with stable bronchiectasis with the expected benefits:1- reduce exacerbation rate2- improve FEV13- may improve CAT score The treatment does not cause serious side effects regarding the safety aspect apart from the fishy odor sensed by the patients .


Article
Study of The Fasting of Ramadan on Asthmatic Patients and The Outcome with Treatment Modification

Author: Ali Salih Baay
Journal: Medical Journal of Babylon مجلة بابل الطبية ISSN: 1812156X 23126760 Year: 2017 Volume: 14 Issue: 1 Pages: 216 -224
Publisher: Babylon University جامعة بابل

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Abstract

Ramadan, the 9th month of Islamic calendar ranging for 29-30 days in duration, during which Muslims are fasting . It was demonstrated that most of the asthmatics Muslim in our regions did not consider asthma to be a problem to Ramadan, and they pass in fasting by arranging their treatment as use the controller inhaler on Iftar and Sohoor time & stop taking the reliever inhaler in the day time. the Aim is to study the effect of Ramadan fasting on the clinical, spirometric figures of patients with stable asthma with treatment modification . Methods: A prospective cohort study was performed before, during and after Ramadan fasting on well-controlled asthmatic patients as they were classified according to the treatment types as:group 1: on inhaled budesonide + formoterol fixed single device (symbicort, Astra Zeneca, sewed) + on need short acting B adrenergic agonist. group 2 : short acting B adrenergic agonist on needed alonegroup 3: interleukins antagonists tablets Once daily (10 mg montelukast Na tablet) + short acting B adrenergic agonist on needed. Results found that fasting seen to have detrimental effects on fasting in hot weather as FEV1, FEF in 50% and asthma control test score show statistically significant differences before & after fasting but patient on inhaled symbicort with treatment modification show better outcome.


Article
The Role of Bronchial Wash Carcino-Embryonic Antigen Assay In The Diagnosis of Non-Small Cell Lung Cancer

Authors: Hashim Mahdi Hashim --- Ali Salih baay --- Ameer Kadhim Al-Humairi
Journal: Medical Journal of Babylon مجلة بابل الطبية ISSN: 1812156X 23126760 Year: 2016 Volume: 13 Issue: 2 Pages: 540 -548
Publisher: Babylon University جامعة بابل

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Abstract

The bronchogenic cancer is one of the most common cancers in human kind & it represents a diagnostic challenge because of the most available tests are either yielding in the late stages or it is some of invasive nature ,so the need for diagnostic test in the early stages is mandatory, aim of the study is to assess the significance of bronchial carcino-embryonic antigen ( CEA) as a tumour marker for aiding the diagnosis of non-small cell lung cancer (NSCLC) and to see if there is any difference between the serum & bronchial CEA and between tumour and non-tumour sidesThirty patients were involved in this study ,divided into 3 groups according to their diagnosis as cancer ,airway disease & Tuberculosis groups, assessment of their socio-demographic features ,clinical features chest X ray ,computerized tomography (CT) scan , fibro-optic bronchoscopy were done & the carcino-embryonic antigen (CEA) level were tested in the samples taken from serum, tumour& non-tumoursides.There was a statistically significant difference in the level of the carcino-embryonic antigen in the bronchial wash of cancer patients group comparing to the serum of the same group & to the bronchial wash level in the other groups in favor of the cancer group patients, but no difference between the tumour& non tumour sides in the cancer group patients.The carcino-embryonic antigen assay in the bronchial wash may be helpful in the diagnosis of non-small cell lung cancer& may be take into consideration in the future work up

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