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Estimation of uric acid in Iraqi women with breast cancer
تقدير حمض اليوريك للنساء العراقيات المصابات بسرطان الثدي

Authors: Ghufran saad nsaif --- Amer Hassan Abdallah --- Najwa Shehab Ahmed
Journal: journal of the college of basic education مجلة كلية التربية الاساسية ISSN: 18157467 Year: 2018 Volume: 24 Issue: 101/ علمي Pages: 91-96
Publisher: Al-Mustansyriah University الجامعة المستنصرية

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Abstract

Breast cancer is the most popular cancer among women and one from the central causes of death between women worldwide although not traditionally considered a tobacco-related cancer, many in vitro and in vivo studies implicate tobacco smoke as a potential breast cancer carcinogen. The results show a significant increase in uric acid at( p<0.05) in both of benign and malignant groups in relation to the controls, it is also observed that there is a non-significant changes (p>0.05) in radiotherapy group. However, smoking shows a non-significant changes of control with patient results of other groups p(>0.05). In conclusion results proposed this is may be a slight increase uric acid levels used to follow the effectiveness of treatment.

سرطان الثدي هو السرطان الأكثر شيوعا بين النساء هو واحد من الأسباب الرئيسية للوفاة بين النساء في جميع أنحاء العالم على الرغم من أن لا تعتبر تقليديا سرطان المرتبط بالتبغ، أن العديد من الدراسات في المختبر وفي الجسم الحي تبين انه ممكن أن يكون دخان التبغ سبب محتمل للإصابة، بسرطان، الثدي. أظهرت النتائج وجود زيادة معنوية في حمض اليوريك في المجموعات الحميدة والخبيثة عند مقارنتها مع مجموعة الأصحاء، أن هناك تغيرات غير معنوية في مجموعات العلاج الإشعاعي، مقارنة مع المجموعات الحميدة والخبيثة. ومع ذلك، يظهر التدخين تغييرات غير معنوية عند مقارنة مجموعة الأصحاء مع نتائج المرضىفي الختام النتائج المقترحة هذا قد يكون هناك زيادة طفيفة في مستويات حمض اليوريك المقاس لمتابعة فعالية العلاج.


Article
Evaluation of Estridiol and Some Antioxidant in Breast Cancer Iraqi Women

Authors: Ghufran Saad Nsaif --- Amer Hassan Abdallah --- Najwa Shehab Ahmed --- Wafaa Raji Alfatlawi
Journal: Al-Nahrain Journal of Science مجلة النهرين للعلوم ISSN: (print)26635453,(online)26635461 Year: 2018 Volume: 21 Issue: 1 Pages: 35-40
Publisher: Al-Nahrain University جامعة النهرين

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Abstract

Cancer is the second reason of deaths worldwide while breast cancer is the more spread cancer in women, comprising 29 % from all cancers that they are affected Samples were obtained from patients undergoing surgery in center from breast cancer in oncology teaching hospital Al-Eluia hospital for woman care All blood samples were taken of the patients (110 women) and divided into four groups benign, malignant, radiotherapy and control group In order to measurement estrogen levels which are influenced by the menstrual cycle, the main groups were furthermore divided into sub-groups, premenopausal and postmenopausal women The mean value ± SE of Body Mass Index (BMI) for control, benign, malignant and radiotherapy breast cancer were showed a non-significant change in the comparison of groups according to the Duncan test Estrogen were increased before therapy but decreased following therapy The levels of malondialdehyde (MDA)were elevated in patients after radiotherapy The mean value ± SE of vitamin E were decreased in studied groups Present study aims to study the effects of serum estrogen, vitamin E and antioxidant status in breast cancer patients

Keywords

Estrogen --- Vitamin E --- MDA --- BMI --- Breast cancer

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