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Article
A Five Years Retrospective Study of Congenital Anomalies at Karbala City, Iraq

Author: Ashwaq Ali Hussein
Journal: Karbala Journal of Medicine مجلة كربلاء الطبية ISSN: 19905483 Year: 2017 Volume: 10 Issue: 1 Pages: 2620-2627
Publisher: Kerbala University جامعة كربلاء

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Abstract

background: Congenital anomalies are one of the commonest causes of disability in the world but the data from community –based studies originating from developing countries are scanty.Objectives: To study the frequency and distribution patterns of congenital anomalies in Karbala city, Iraq during five years and to find any related aetiological factor for congenital anomalies occurrence.Materials & Methods: It is a retrospective study includes all appearant congenital anomalies in newborns during January2011-December2015.The data were collected from the neonatal care unit admission register & a specific register of recording congenital anomalies according to ICD-10(International classification of diseases &related health problems-10th revision) that’s introduced by WHO.The data were collected at the Karbala teaching hospital for pediatric where majority of sick newborns care occurs in this city. Variables were represented in a frequency tables & column charts.Results: The total enrolled cases of congenital anomalies in five years were 327 that’s form 9.19% of total admission to the neonatal care unit in our hospital(3586) ,the highest percentage were anomalies of the cardiovascular system(29.36%) followed by the gastrointestinal system(27,83%) then the musculoskeletal system (13.76%) and the least percentage was of cutaneous system(1.83%).Individually, there was a fluctuating increment in overall prevalence during the study period, but the highest numbers in 2014 & the least in 2012.Higher percentages for the urban residency, 18-35 years old maternal group, families of positive consguanity, & multipara’s mothers.Conclusions& recommendations: preponderance of the malformations of the cardiovascular system despite the underestimation of them due to delayed exhibition of symptoms so there are a great benefit from screening for a hidden congenital heart anomalies., I invite all countries for searching congenital anomalies & I recommend encouragement of higher education researchers to study genetic specialty & preventive health services as our country really required such services in addition to proper preparation of health care staffs.Keyword: Congenital anomalies, retrospective study, neonatal care unit, Karbala, Iraq


Article
The Effect of Birth Asphyxia on the Coagulation Status in Neonates

Authors: Ashwaq Ali Hussein --- Hithab Jawad Muhsen --- Rajaa Jabbar Kadhum
Journal: Karbala Journal of Medicine مجلة كربلاء الطبية ISSN: 19905483 Year: 2017 Volume: 10 Issue: 2 Pages: 2719-2724
Publisher: Kerbala University جامعة كربلاء

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Abstract

background: Birth asphyxia has multi system effect, which predisposes to coagulopathy by enhancing consumption of platelets & some clotting factors as a results of the associated sever hypoxemia, acidaemia & sepsisObjective: To study the effects of birth asphyxia & perinatal events on the coagulation status of newborn infants. Patients & Methods: Across sectional study was done on 27 neonates with birth asphyxia in AL-Zahraa teaching hospital in Najaf city from period of first of February 2012 to first of July 2012. Blood samples were collected from the neonates within the first 24 hrs. After birth and sent for investigations including PT, PTT, plasma fibrinogen and platelet count.Results: The study showed statistically significant effect of birth asphyxia on platelet count especially in severely asphyxiated neonates with Apgar score of 0 – 3 at 5 min after birth (plat. Count < 100,000 per mm3) in comparison to neonates with Apgar score of 4 – 6 at 5min after birth. Infants who have very low birth wt. (i.e. <1500 gms) had significantly lower platelet count (< 100,000 per mm3) than infants with birth wt.>1500 gmsBirth asphyxia had no significant effect on PT, PTT, or fibrinogen level. Other perinatal and prenatal variables examined as (sex, maternal hypertension, DM, mode of delivery gestational age) did not show any significant association with coagulation status.Conclusion: Thrombocytopenia (plat. <100.000 per mm3) is seen in neonates with Apger score (0-3) at 5 min. and in neonates with very low birth wt. <1500gms). No statistically significant relation between birth asphyxia and PT, PTT and plasma fibrinogen level.

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