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Article
Electrocardiograph and Echocardiograph Electrocardiograph and Echocardiograph Electrocardiograph

Author: Basil N.Saeed*
Journal: Iraqi Academic Scientific Journal المجلة العراقية للاختصاصات الطبية ISSN: 16088360 Year: 2012 Volume: 11 Issue: 2 Pages: 199-204
Publisher: The Iraqi Borad for Medical Specialization المجلس العراقي للاختصاصات الطبية

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Abstract

ABSTRACT:BACKGROUND:Rheumatoid arthritis (RA) is a systemic autoimmune disease with characteristic feature of persistant inflammatory synovitis in symmetrical distribution; it has a higher incidence of fatal and non-fatal cardiovascular events which account for half of all death in RA patients.OBJECTIVE:To study the cardiac involvement in long standing rheumatoid arthritis patients in comparison to healthy persons by electrocardiograph and echocardiograph.PATIENTS AND METHODS:A sample of 100 Iraqi patients with long standing rheumatoid arthritis and 100 healthy individuals who served as control group matched for sex and age were selected after exclusion of risk factors (hypertension, diabetes mellitus, smoking and previous cardiac problems), both groups were studied by electrocardiograph and echocardiograph under supervision of a cardiologist.RESULTS:There were a significant number of patients with rheumatoid arthritis having abnormal electrocardiographic findings 21(21%) in comparison to healthy persons 7(7%) (P-value 0.004), also there were significant number of rheumatoid arthritis patients with abnormal echocardiographic findings 36(36%) in comparison to healthy individuals 11(11%) (P-value o.ooo).while there were no significant association between disease duration and type of medications with cardiac abnormalities reported in this study.CONCLUSION:There is an increase of asymptomatic cardiac structural abnormalities in chronic rheumatoid arthritis patients in comparison to normal healthy individuals as detected by electrocardiograph and echocardiograph.


Article
Interpretation of Clinical, Radiological, Electrocardiographic and Echocardiographic Findings in Pulmonary Hypertension

Author: Basil N. Saeed
Journal: Iraqi Academic Scientific Journal المجلة العراقية للاختصاصات الطبية ISSN: 16088360 Year: 2007 Volume: 6 Issue: 2 Pages: 84-87
Publisher: The Iraqi Borad for Medical Specialization المجلس العراقي للاختصاصات الطبية

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Abstract

ABSTRACT:OBJECTIVE:To make correlation between clinical radiological electrocardiographic and echocardiographic findings in cases of Pulmonary Hypertension.METHODS:140 patients refered to the medical departments, Baghdad Teaching Hospital ( 90 of them admitted in this study were as follow);(52 (47%) cases having Ischemic heart disease,28(25%) cases having C.O.P.D., 10(9%) cases having connective tissue diseases, 9(8%) cases of Rehematoid Arthritis, 1 case S.L.E.). The remaining 50 cases were excluded from the study because they have another chronic disorder like Diabetus mellitus, Renal failure, Malignancy, Skeletal deformity.Fourty normal volunteers were admitted in this study both groups were assessed clinically, radiologically, electrocariograpically, echocardiographically plus the routine blood tests including F.B.S, B.urea,lipid profile.RESULTS:90 cases of patients admitted in this study showed variable findings the prominent finding was loud pulmonary sound "p2" in 100% of cases, 19.6% of cases showed cardiomegaly, 33% prominent pulmonary marking, 11.4% percardial effusion, 28% Right Ventricular Hypertrophy.CONCLUSION:It is not necessary to find all the clinical, radiological, electrocardiographic and the echocardiographic changes in any patient with pulmonary hypertention>30 mm Hg.


Article
Extent of Coronary Arteries Disease Between Angiographic FIndings and Some Atherogenic Lipid inDices

Author: Basil N. Saeed
Journal: Iraqi Academic Scientific Journal المجلة العراقية للاختصاصات الطبية ISSN: 16088360 Year: 2011 Volume: 10 Issue: 2 Pages: 166-169
Publisher: The Iraqi Borad for Medical Specialization المجلس العراقي للاختصاصات الطبية

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ABSTRACT:BACKGROUND:Modification of lipid subtypes improves the prognosis of ischemic heart disease.OBJECTIVE:Correlating the coronary angiographic finding with the measurement of different plasma lipid parameters.PATIENT AND METHODS:(180) hundred eighty patients admitted in the study, (120) patients were male, (60) patient were female, their age range (29-72 years) were randomly assigned into four groups.Group (1): Patient with myocardial infarction (STEMI).Group (2): Patient with non-STEMI myocardial infarction.Group (3): Patient with unstable angina.Group (4): Patient with ischemic cardiomyopathy.The angiographic findings, were classified according to the guidelines of (ACC/AHA) all patients had lipid parameters correlated to their angiographic finding (A, B, C, respectively).RESULTS:This study showed that there was significantly correlated between the levels of HDL, LDL, triglyceride and the coronary angiographic findings in groups (A, B, C) (0.05, 0.001, 0.001) respective. However the use of Atherogesic index (TG/HDL-c) was highly significant and nave clinical evaluation the severity of extent of coronary artery disease (i.e. the Raton (5.9) in group A, (5.2) in group B, (4.8) croup C).CONCLUSION:Using more than one lipid parameter can assess the severity of coronary artery disease.


Article
Insight on the Side Effects of Lipid Lowering Agents (Statin) in Iraqi Patients with Ischemic Heart Diseases

Author: Basil N. Saeed
Journal: Iraqi Academic Scientific Journal المجلة العراقية للاختصاصات الطبية ISSN: 16088360 Year: 2009 Volume: 8 Issue: 3 Pages: 266-269
Publisher: The Iraqi Borad for Medical Specialization المجلس العراقي للاختصاصات الطبية

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ABSTRACT:BACKGROUND:3-hydroxy-3methyl glutaryl co enzyme inhibitor (MMG-COA) (statin) is a very common drug used in many medical conditions regardless of the presence or absence of dyslipidemia. One of these conditions is the cardiac disorders.OBJECTIVE:Throwing a light on the prevalence of their side effects in Iraqi patients.PATIENTS AND METHODS:Two hundred seventy patients with ischemic heart disease from the period of November 2006-November 2007 referred to Baghdad teaching hospital (the medical city). Those cases were using statin and grouped into two groups.Group A: patients admitted with acute coronary syndrome (myocardial infarction and unstable angina) (230 patients 77%).Group B: patients with associated risk factors (Hypertension, diabetes mellitus, smoking and secondary lipidemia) 40 cases 23%, have history of ischemic heart disease on treatment they use the drug in range of (10-40) daily with review monthly for the side effects. All 270 cases were free from other organic disorders (i.e. renal, thyroid, malignancy, or any longstanding disease). All patients went through a questionnaire which includes: age, gender, risk factors (Hypertension, diabetes mellitus, smoking, and lipidemia), routine blood tests, lipid profile, liver function tests, C-reactive proteins, thyroid function tests, chest X-ray, electrocardiography and echocardiography done for all patients, all patients used to take drugs in the range of 10-40mg daily for at least one year.RESULT:The side effects noticed in this study were gastric, musculoskeletal, elevated liver enzymes (40%, 28.9%, and 1% respectively from the total number of patients). Other side effects in other systems like skin, respiratory, and cardiac were not encountered.CONCLUSION:This study showed that the side effects of statin were not involving all the body systems.


Article
Psychiatric Disorders in Cardiac Patients

Author: Basil N. Saeed
Journal: Iraqi Academic Scientific Journal المجلة العراقية للاختصاصات الطبية ISSN: 16088360 Year: 2009 Volume: 8 Issue: 1 Pages: 85-89
Publisher: The Iraqi Borad for Medical Specialization المجلس العراقي للاختصاصات الطبية

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ABSTRACT:BACK GROUND:Psychiatric disorders and coronary heart disease are not uncommonly seen together in the same patient especially in association with myocardial infarction these disorders vary from simple anxiety, depression, posttraumatic stress disorder, adjustment disorder.OBJECTIVE:Studying the depressive disorders in the Iraqi cardiac patients and its prevalence after April 2003. and trying to ascertain any mispractice in management of such patients by ignoring the psychiatric cause.METHODS:260 patients admitted to Baghdad teaching hospital medical departments over the period December 2005- October 2007. Those patients were having cither stable angina unstable angina and myocardial infraction. A uniform questionnaire was used for all patients to find out the prevalence any psychiatric disorders.RESULTS:This study showed the presence of depression during the pre and post cardiac events in 70 cases (27%) anxiety was also a very common problem in about 60 cases (23%), however the percentage of patients whom were had psychiatric disorders after an acute events due to un settled security in the country since 2003 were as follow depression (21% cases 8%) from the total number of cases respectively.CONCLUSION:Psychiatric disorders are becoming a common problem in many Iraqi cardiac patients because of the difficulties of their daily life since 2003 and it represents about 50% of the cases of psychiatrics disorders. This may make it an important issue to use antidepressant drugs in many of those patients


Article
Cystatin (C) and its correlation to ischemic heart disease

Author: Dr. Basil N. Saeed
Journal: Al-Kindy College Medical Journal مجلة كلية الطب الكندي ISSN: 18109543 Year: 2015 Volume: 11 Issue: 2 Pages: 15-16
Publisher: Baghdad University جامعة بغداد

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Abstract

Background: Cystatin C is recently considered to be a good predictor of cardiovascular morbidity and mortality in patients with coronary artery disease (CAD)Objectives: Correlation between cystatin and ischemic heart disease.Methods :One hundred forty patients (140) with ischemic heart disease admitted to thin study at Baghdad teaching hospital from the period June. 2011 to Jan. 2012. Those patients was categorized into three groups.Group (A): patients with ischemic heart failure.Group (B): Patients with myocardial infarction.Group (C) patients with unstable angina.All these groups were in comparison to fifty (50) healthy controls. Fasting serum citation (C) were measured in all patients and control in addition to all other routine investigations.Results: All results of serum cystatin C in all three groups of patients were higher in comparison to control group (P. value < 0.05) while it was not significantly different between the three groups (P. value 0.05)Conclusion: Cytstatin C can be used as prognostic biomarker in patients with ischemic heart and its complicated.


Article
The habitual use of plant alkaloids and the prevalence of myocardial diseases.

Author: Basil N. Saeed باسل نجيب
Journal: Journal of the Faculty of Medicine مجلة كلية الطب ISSN: 00419419 Year: 2010 Volume: 52 Issue: 1 Pages: 19-22
Publisher: Baghdad University جامعة بغداد

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Abstract

Background: The plant (Khat) contains at least 40 types of alkaloids. It has an adrenergic like effect especially on the heart one of these alkaloid is cathedulins group which has molecular height of 600-1200mm.I/L. it is used frequently mainly at the African horn region (e.g. yemen). This plant alkaloids used by people in form of bands (each band is about 50gm, two bands 100gm and so on).Patients and methods: Three groups of Patients have been included in this study. Group A: (30) patients with dilated cardiomyopathy, Group B: (50) patients with history of ischemic heart disease with clinical presentation of ischemic cardiomyopathy and Group C: (80) cases (50 cases of ischemic cardiomyopathy, 30 cases dilated cardiomyopathy). Used as control group to see the difference from stopping the Khat without adding any medication during the follow up peroid this was over a year with monthly checkup. The place of this was Yemen-Sannaa general hospital and Sannaa private international clinic.Results: This study showed that the age range of patients and volunteers was similar, mean age (35-65 years), all were male because this plant is used by most of the males and there was difficulty in discussing this problem with the female these three groups were categorized into two groups according to the amounts of all khat bands consumed.Group1: people using about 50gm of this plant and did comprise 75% of all the cases.Group2: people using about 50-150gm of this plant and comprising 25% of all the cases.This study did not show any significant correlation between the incidence of dilated cardiomyopathy and the chronic use of this plant alkaoild, also there was no correlation between the duration of using this alkaloid and probability of getting these cardiac disorders. Stopping consuming this alkaloid did not change the clinical feature dramatically except reduction of liver enzymes elevation.Conclusion: No significant correlation between using the plant khat and development of ischemic and non ischemic dilated cardiomyopathy.Keywords: Khat, Myocardial Disease.

Keywords

Khat --- Myocardial Disease.


Article
Association of Fibrinogen as a Myocardial Infraction Risk Factor in Men

Authors: Basil. N. Saeed --- Eman Sh. AL-Obeidy
Journal: Journal of the Faculty of Medicine مجلة كلية الطب ISSN: 00419419 Year: 2010 Volume: 52 Issue: 4 Pages: 392-394
Publisher: Baghdad University جامعة بغداد

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Abstract

Background: Acute myocardial infarction (AMI) is an irreversible myocardial injury and necrosis caused by serious and long term ischemia. Fibrinogen is considered as
one of the probable risk factors of myocardial infarction.
Patients and methods: 1.8-mL venous blood specimen from 40 patients with MI and 50 control subjects was obtained and put it into tubes containing 0.2 mol/L trisodium citrate. Plasma fibrinogen level was determined by the method of Clauss (Diagnostic Stago, France). Results The mean age of patients was (45.2 ± 6) years in patients with premature myocardial infarction and (45.06±5) years in the control group (p =0.07). There were no statistically significant relationships between the two groups in history of premature myocardial infarction in their first-degree relatives (p =&#61472;0.05), cigarette smoking (p =&#61472;0.06), diabetes (p =&#61472;0.08), or hypertension (p =&#61472;0.071). The mean plasma fibrinogen in patients (495 ±10.2mg/dL) was elevated markedly compared with the control group (465±8.4 mg/dl) ( p =&#61472;0.01) . Hyperfibrinogenemia (>450 mg/dL) was detected in 87.5% of patients and 52.0% of controls. Conclusion: This study introduced fibrinogen as a risk factor for premature coronary artery disease in Iraqi men


Article
H. Pylori Infection in Iraqi patients with ischemic heart diseases

Authors: Basil. N. Saeed ايمان العبيدي --- Eman Sh. AL-Obeidy
Journal: Journal of the Faculty of Medicine مجلة كلية الطب ISSN: 00419419 Year: 2011 Volume: 53 Issue: 1 Pages: 29-31
Publisher: Baghdad University جامعة بغداد

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Abstract

Background: Cardiovascular diseases are among the most common cause of death in Developed countries. In addition to traditional risk factors for cardiovascular disease, nowadays, accumulating evidence indicates that a variety of infectious agents may contribute to pathogenesis of ischemic heart disease.Patients and methods: 125 patients (25 females and 100 males) attending the department of cardiology, Baghdad, teaching hospital over the period December 2008- June 2009were enrolled. Their age range between (39-75 years) compared with 50 healthy individuation (Age & sex matched).The sera were tested for H. pylori antibodies using enzyme linked immunosorbent assay (ELISA).Results: 80% of patients showed the anti-H. Pylori IgGs (P < 0.05). But there were no significant association between risk factors & H. pylori infection (P > 0.05).Conclusions: These findings raise the possibility that exposure to H. pylori may lead to increased risk of coronary artery disease independent of other risk factors.Keywords: coronary artery disease, Helicobacter pylori, RAO


Article
The Value of Using Echocardiography in Patients of Advanced Liver Disease with Cardio Pulmonary Complications

Authors: Basil. N. Saeed --- Sameer Hakeam --- Lutf Ahmed --- Jalal Ahmed
Journal: Iraqi Academic Scientific Journal المجلة العراقية للاختصاصات الطبية ISSN: 16088360 Year: 2009 Volume: 8 Issue: 4 Pages: 323-326
Publisher: The Iraqi Borad for Medical Specialization المجلس العراقي للاختصاصات الطبية

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ABSTRACT:BACKGROUND:Patients with chronic liver disease are liable to get cardio – pulmonary complications, one of these complications is development of pulmonary hypertension ranging from mild to it's sever form – this complication could give some abnormal findings in chest x-ray, electrocardiography but more prominently by echocardiography.OBJECTIVES:To clarify the benefit of using the echocardiogram is detecting pulmonary hypertension prior to the use of invasive methods (catheterization) in patients with advanced liver disease.METHODS:A total of 50 patients with chronic liver diseases (cirrhosis, chronic active hepatitis) their age range is (25-70 years) (mean are 37.07 years), the fifty patients were free from any cardiac or respiratory diseases.The study extending from December 2007-August 2008. All patients went through full history and routine blood test: including complete blood picture, fasting blood sugar, blood urea & screatinne, lipid profile, liver function tests, clinical examination, and investigations included routine blood test, chest x-ray, and electrocardiography, echocardiography (Transthoracie and transoesphageal). The child-Pugh score used for assessing the severity and prognosis of chronic liver disease and it classified into three groups (A, B, C) used in this study.RESULTS:Fifteen patients from the 50 cases (30%) only proved to have cardio-pulmonary changes (i.e. pulmonary hypertension right ventricular hypertrophy and dilatation with the mean value of ≥ 25mm Hg at rest or ≥ 30mm Hg during exertion) those patients were having fatigue in (70%) of them while dysponea, chest pain, cyanosis, syncope were detected in 30%, 10%, 1%, 2% respectively in those cases of pulmonary hypertension with chronic liver disease.CONCLUSION:The use of non invasive methods especially echocardiography were helpful in detecting the presence of pulmonary hypertension in patients with chronic liver disease

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