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Article
Transverse Myelitis: Story of Fifteen Years of Dependence on Mechanical Ventilation

Author: Basim.S. Al‐Mgoter
Journal: Mustansiriya Medical Journal مجلة المستنصرية الطبية ISSN: 20701128 22274081 Year: 2009 Volume: 8 Issue: 1 Pages: 65-66
Publisher: Al-Mustansyriah University الجامعة المستنصرية

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Abstract

This is a story of a patient with 27 years old; he had spent 12 years of his life enjoying a good health and living as a lovely child among his family, his father, mother and other brothers and sisters. Wail Hadi Hassan was looking forward to a life filled with happiness and hope and suddenly he found himself inside the hospital, he was admitted to the hospital and since that time he couldn`t leave.

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Article
Anti-Tuberculous Induced Hepatotoxicity

Author: Basim S. Al-Mgoter
Journal: Mustansiriya Medical Journal مجلة المستنصرية الطبية ISSN: 20701128 22274081 Year: 2010 Volume: 9 Issue: 1 Pages: 52-56
Publisher: Al-Mustansyriah University الجامعة المستنصرية

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Abstract

Background Anti-tuberculous drugs can induce liver injury. Although, it is usually mild and transient, but it can be presented in a form of markedly severe liver injury. Objective To assess the severity of hepatic injury that can be induced by the anti-tuberculous drugs and to evaluate the effect of different demographic features, duration of therapy and the presence of any other risk factors for liver injury on the frequency of anti-tuberculous drugs induced hepatotoxicity. Methods This cross sectional study had enrolled 30 patients who were on quadruple anti-tuberculous therapy regimen (Rifampicin and Isoniazid for 6 months and Pyrazinamide with streptomycin for the initial 2 months). They were randomly selected from those patients who had attend the outpatient clinic or admitted in the medical wards of Al-Yarmouk Teaching Hospital during the period between the 1st of Feb. 2006 to the 31st of January 2007. Results This study had enrolled 30 patients, 7 of them were female (23.3% of the sample), and 23 were male (76.7% of the sample). Male to female ratio was 3.28:1. This study revealed that 73.3% of those patients included in this study were older than 50 years old. 86.7% of the sample had less than 3 folds increase in their serum alanine aminotransferase (26 patients), only 4 patients (13.3% of the sample) had more than 3 fold increase in their serum alanine aminotransferase level more than the upper limit of normal range. 73.3% of the sample had increased serum bilirubin level by less than 3 times the upper limit of normal range. 46.7% of the sample (14 patients) were underweight. 70% of the sample (16 patients) had been included in this study within the first 2 months of anti-tuberculous therapy. 7 patients give history of regular alcohol intake (23.3% of the sample). While 4 patients had been discovered to be hepatitis B positive (13.3% of the sample). Jaundice was found in 9 patients (30% of the sample). Conclusion This study revealed that severe anti-tuberculous drugs induced liver injury is uncommon, increasing age is an important risk factor. It is unusual to find marked and very high level of alanine aminotransferase and bilirubin in patients using anti-tuberculous drugs. Being underweight can be regarded as a factor that may increase the risk of hepatotoxicity. Most of the cases of liver injury occur early from starting therapy. The presence of other risk factors that can induce liver injury can increase the risk of anti-tuberculous drug induced hepatotoxicity.


Article
Transverse Myelitis: Story of Fifteen Years of Dependence on Mechanical Ventilation

Authors: Basim.S. Al-Mgoter --- Nabeel Suleiman
Journal: Mustansiriya Medical Journal مجلة المستنصرية الطبية ISSN: 20701128 22274081 Year: 2008 Volume: 7 Issue: 2 Pages: 65-66
Publisher: Al-Mustansyriah University الجامعة المستنصرية

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Abstract

This is a story of a patient with 27 years old; he had spent 12years of his life enjoying a good health and living as a lovely child among his family, his father, mother and other brothers and sisters. Wail Hadi Hassan was looking forward to a life filled with happiness and hope and suddenly he found himself inside the hospital, he was admitted to the hospital and since that time he couldn`t leave.

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Article
Pulmonary Tuberculosis in Patients with Diabetes Mellitus
التدرن الرئوي عند مرضى السكري

Authors: Samir B. Al-Adhami أ.د. سمير بشير الأعظمي --- Basim S. Al-Mgoter د. باسم صافي المكوطر
Journal: IRAQI JOURNALOF COMMUNITY MEDICINE المجلة العراقية لطب المجتمع ISSN: 16845382 Year: 2008 Volume: 21 Issue: 1 Pages: 47-54
Publisher: Al-Mustansyriah University الجامعة المستنصرية

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Abstract

Abstract:Background: Diabetes Mellitus is associated with higher risk of lower respiratory tract infection including pulmonary tuberculosis with features which differ from that observed in the general non-diabetic population.Objective: To assess the effect of diabetes mellitus on the clinical, bacteriological and radiological presentation of pulmonary tuberculosis in diabetic population.Methods: This is a cross sectional study that enrolled 25 patients with diabetes mellitus and pulmonary tuberculosis. The patients included in this study had been randomly selected from those attending Al-Yarmouk Teaching Hospital in Baghdad-Iraq during the period between the 1st of June, 2003 to the 31st of May, 2004. All of the patients had been subjected to thorough physical examination and laboratory investigations. Results: This study revealed male to female ratio of 5:1. Sixteen percent of the sample (4 patients) was of type 2 diabetes mellitus. 56% of those with diabetes and pulmonary tuberculosis (14 patients) were diabetic for 0-10 years. 19 patients (76% of the sample) had sputum smear positive, the remaining 6 patients (24% of the sample) were smear negative/culture positive. Multiple lobe involvement was obvious in 64% of (16 patients). Lower lung field involvement had been detected in 32% of the sample (8 patients). Cavitary lesions had been diagnosed in 15 patients (60% of the sample). Conclusions: This study revealed that diabetes modifies the clinical and radiological picture of pulmonary tuberculosis. Diabetic patients are at higher risk of recurrence and extensive pulmonary involvement. Tuberculosis is associated with poor glycemic control. Diabetes changes the male: female ratio toward the side of male predominance. Lower lung field involvement is more common in diabetics who had pulmonary tuberculosis. Keywords: Pulmonary, tuberculosis, diabetes.

الملخص:الخلفية: يتزامن مرض السكر مع زيادة في نسبة خطورة الأصابة بالإلتهابات الخمجية للجزء السفلي للجهاز التنفسي بضمنها إصابات التدرن الرئوي و بخواص تختلف عن تلك الملاحظة عند عامة الناس من غير المصابين بداء السكريالهدف: تقييم تأثير مرض السكر من الناحية السريرية، الجرثومية و الشعاعية على المرضى المصابين بالتدرن الرئوي.الطرق: تتضمن هذه الدراسة 25 مريضاً مصاب بداء السكري و التدرن الرئوي. تم إختيار المرضى بصورة عشوائية من المرضى المراجعين لمستشفى اليرموك التعليمي في بغداد خلال المدة المحصورة بين الأول من حزيران 2003 إلى 31/آيار/2004. النتائج: خلال هذه الدراسة وجد أن نسبة الذكور إلى الأناث 5 إلى 1. 16% من العينة (4 مرضى) هم من مرضى السكري النوع الثاني. 56% هم من مرض السكر و التدرن الرئوي (14 مريض) و مدة مرض السكري من 0-10 سنوات. 12% من العينة (3 مرضى) لديهم نسبة السكر 120 ملغم/ديسي لتر أو أقل. 84% من العينة (16 مريض) لديهم مستوى خضاب الدم السكري هو 7% أو أكثر. 24% من العينة (6 مرضى) لديهم تأريخ سابق بالأصابة بمرض التدرن الرئوي. 19 مريض (76% من العينة) لديهم مسحة القشع موجبة، 64% (16 مريض) تبين إصابة أكثر من فص واحد من رئتيهم بالتدرن كما تبين إصابة المنطقة السفلى من الرئة في 32% من العينة (8 مرضى). الخاتمة: تبين من هذه الدراسة أن داء السكري يحدث تغيرات سريرية و شعاعية عند المرضى المصابين بالتدرن الرئوي. مرض السكر أكثر خطورة بالنسبة لعودة التدرن الرئوي و كذلك شدة إنتشاره في الرئة. التدرن الرئوي يتزامن مع عدم السيطرة بمرض السكر. مرض السكر يغير نسبة الذكور إلى الإناث بإتجاه الذكور. المنطقة السفلى من الرئة هي أكثر عرضة للأصابة عند مرضى السكري المصابين بالتدرن الرئوي.

Keywords

Pulmonary --- tuberculosis --- diabetes.

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