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Article
The role of Trace Elements (Zinc, Copper, Magnesium and Calcium) in Pregnant Women with Preeclampsia in third trimester and fetal cord blood after delivery

Author: Basima Sh. Alghazali
Journal: Muthanna Medical Journal مجلة المثنى الطبية ISSN: 2226146x Year: 2014 Volume: 1 Issue: 1 Pages: 16-26
Publisher: Al-Muthanna University جامعة المثنى

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Abstract

Trace element such as zinc and copper display antioxidant activity and act as peroxynitratescavenger while others such as magnesium and calcium essential micronutrients. The aim of thisstudy to determine the status of these elements in preeclamptic pregnant women and to find anyrelationship between changes in serum level of zinc, copper, magnesium and calcium inpreeclamptic women and healthy women and to assess the relation to severity of the disease in AlNajef city. The patients included in this study were divided into two groups control group who are normotensive (50) and study group who are preeclampsia (50 patients, 31 mild preeclampsia and 19 severe preeclampsia). Parameters include age, parity, urine albumin, liver function test, renal function test and platelets count. Maternal blood aspirated and cord blood sample taken to measure serum copper, zinc, magnesium and calcium using commercial kits. There is significant decrease in the level of trace elements between the control and preeclamptic groups. The mean serum level of calcium, magnesium, copper and zinc between the preeclamptic group and control group was significantly different. It seems that these trace elements are involved in the pathogenesis of preeclampsia.

Keywords

Preeclampsia --- Zinc --- Copper --- Magnesium --- Calcium --- Cord blood


Article
The association of C-reactive protein in the pathogenesis of meconium stained amniotic fluid in Al- Najaf city

Author: Basima Sh. Alghazali
Journal: Muthanna Medical Journal مجلة المثنى الطبية ISSN: 2226146x Year: 2015 Volume: 2 Issue: 2 Pages: 65-69
Publisher: Al-Muthanna University جامعة المثنى

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Abstract

The objectives of this study is to study the association of C-reactive protein in the pathogenesisof meconium stained amniotic fluid in women presented in labour. A case control study, 90women presented in labour 45 with meconium stained amniotic fluid (MSAF) and 45 clearamniotic fluid (CAF), from March 2013 to July 2013 in the labour room and operative theater.Data collected regarding their age, gestational age, mode of delivery, neonatal outcome, parityand maternal blood for C- reactive protein. Complete physical examination of the neonateregarding Apgar score, color of baby, response to a catheter in the nostril, muscle tone, heart rate and breathing was done. There was a significant increment in the level of C- reactive protein in women with MSAF. We concluded that C- reactive protein may be involved in the pathogenesis of MSAF.

Keywords

C-reactive protein --- MSAF --- CAF


Article
The Role of C-Reactive Protein and Visfatin in Pathogenesis of Preterm Labor in Al- Najaf City

Authors: Basima Sh. Alghazali --- Seenaa Ali Hussein
Journal: Medical Journal of Babylon مجلة بابل الطبية ISSN: 1812156X 23126760 Year: 2014 Volume: 11 Issue: 4 Pages: 785-791
Publisher: Babylon University جامعة بابل

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Abstract

Background:Visfatin is adipokine originally discovered as a pre- B-cell colony enhancing factor, is expressed by amniotic epithelium,cytotrophoblast,and deciduas and is over expressed when fetal membrane are exposed to mechanical stress or inflammatory stimuli.Objective: To determine whether preterm labour is associated with changes in maternal plasma circulating C-reactive protein (CRP) and visfatin concentrations.Study design: This is a case control study.Setting: The department of Gynecology and Obstetrics in the college of medicine in Kufa University.Materials and Method: The patients included in this study were divided into three groups control group who are preterm not in labor(50) and cases group who are preterm in labor(50) and full term group in labor(50). Parameters include age, gestational age, general urine examination, liver function test, renal function test, white blood count, hemoglobin, c-reactive protein (CRP), and visfatin.Results: There is a significant increment in the level of C-reactive protein and visfatin between cases and control groups .Conclusion: The visfatin and c-reactive protein may be involved in the pathogenesis of preterm labor.


Article
Embryo Grade I is The Most Important ICSI Parameters That Predict Intracytoplasmic Sperm Injection(ICSI) Outcome

Authors: Ban J. Edan --- Sami R.Al-Katib --- Basima Sh.AlGhazali
Journal: Medical Journal of Babylon مجلة بابل الطبية ISSN: 1812156X 23126760 Year: 2015 Volume: 12 Issue: 1 Pages: 264-272
Publisher: Babylon University جامعة بابل

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Abstract

The aim of this study was to compare different intracytoplasmic sperm injection (ICSI) parameters with its outcome and predict the most important factor that relate with successful rate.A total seventy-five infertile women aged between 22-45 years(31.43 ± 5.38 years), referred to the fertility clinic in Al-Sadder teaching hospital, , and undergone intracytoplasmic sperm injection throughout period from March 2013 to January 2014,were included in this study. Fertilization rate (FR) and cleavage rate was calculated. The embryos grading was evaluated according to their morphology and percentage of fragmentation. The biochemical pregnancies was confirm on the fourteenth day of embryo transfer by measurement of serum human chorionic gonadotrophine ( B- HCG ). Out of the 75 included patients, 15 (20%) achieved pregnancy after ICSI. Pregnant women were associated (P < 0.05) . Total oocyte retrieved , stage metaphase II oocyte , pronucleus , cleavage rate , grade I ,total number of embryos ,and number of transferred embryo significantly higher in pregnant women when compared with non-pregnant women(P<0.05) Analysis of ROC curve revealed that area under the curve for number of grade I embryos was 0.868 for predicting pregnancy followed by followed by MII (0.815), number of total oocyte .retrieved and PN (0.773), ET( 0.767) and total number of embryos(0.758) respectively.Data show that the number of grade I embryos is the better at predicting for successful pregnancy outcome.(higher test result give more positive test).

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