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Evaluation of Hematocrit Level, Red Blood Cells and White Blood Cells Counts in Blood from Patients with Different Severities of Periodontal Diseases

Authors: Maha Abdul Aziz Ahmed --- Chinar Jabbar Ali
Journal: Journal of baghdad college of dentistry مجلة كلية طب الاسنان بغداد ISSN: 16800087 Year: 2018 Volume: 30 Issue: 3 Pages: 1-6
Publisher: Baghdad University جامعة بغداد


Background: Anemia of chronic disease (ACD) occurs in the presence of chronic infection, inflammatory conditionsor neoplastic conditions despite of adequate iron and vitamins storage. Gingivitis is the inflammation of the gingiva,periodontitis is the inflammation in the periodontium that extend deeper with loss of connective tissue attachmentand supporting bone. The main pathogenesis of periodontal diseases and ACD is immune activation.Aims of study: Determine and compare the clinical periodontal parameters (plaque index (PLI), gingival index (GI),bleeding on probing (BOP), probing pocket depth (PPD) and clinical attachment level (CAL)). Evaluate thehematocrit (Hct) level, red blood cells (RBCs) count and white blood cells (WBCs) count. Assess the correlationsbetween the clinical periodontal parameters and hematological parameters at patients had gingivitis, chronicperiodontitis (CP) with different severities (mild, moderate and severe) with healthy periodontium subjects.Materials and Methods: 35-50 years old, 150 male subjects were included in this study. They were divided into threestudy groups: group of 30 patients with gingivitis, group of 90 patients with CP which subdivided into (Mild CP=30patients, Moderate CP =30 patients, Severe CP =30 patients) and control group 30 subjects with clinically healthyperiodontium. Blood samples were collected then by automated blood analyzer the Hct, RBCs and WBCs wereevaluated.Results: Comparisons among groups and subgroups revealed significant differences in Hct and WBCs, while RBCswas non-significant. Means values of RBCs count showed reduction in mild and severe CP subgroups. while, the Hctand WBCs mean values increased in patients with periodontal disease. The correlations between the clinicalperiodontal parameters with WBCs and RBCs were almost non-significant but, with Hct was mostly significantnegative correlations.Conclusion: Inflammatory and immune responses in periodontal diseases caused change in different hematologicparameters which could contribute to the development of anemia of chronic disease.

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