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Correlation of Fetuin A level with ECG types of Acute Myocardial Infarction

Authors: Haydar Hashim Al-Shalah --- Oday Al-Salihi --- Dina Ayed Mohammed
Journal: Medical Journal of Babylon مجلة بابل الطبية ISSN: 1812156X 23126760 Year: 2016 Volume: 13 Issue: 4 Pages: 750 -754
Publisher: Babylon University جامعة بابل

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Abstract

Acute myocardial infarction is one of the commonest disease with serious complications and increasing morbidity and mortality. Coronary atherosclerosis plays a crucial role in the underlying pathophysiology. Fetuin-A is a protein which is closely linked with increased risk of cardiovascular disease, and secreted mainly by the liver, produces subclinical inflammation and insulin resistance. This study was aimed to evaluate the association of serum fetuin A level with ECG types of acute myocardial infarction.This is a case–control study included 88 subjects divided into two groups; 44 patients with acute myocardial infarction,36 of them with STEMI and 7 with NSTEMI. The other 44 were apparently healthy individuals taken as a control. Serum fetuin-A levels were measured by using ELISA technique. There was significant differences in serum fetuin-A levels between patients and control, (p value ≤ 0.05).The mean differences between serum fetuin-A levels and both type of AMI (STEMI and NSTEMI),were also significant(p value ≤ 0.05) where higher values observed in STEMI.This study concluded thatfetuin-A level was significantly correlated with type of AMI and higher values of fetuin-A were observed in STEMI .

Keywords

Fetuin-A --- AMI --- ELISA technique --- STEMI --- NSTEMI --- ECG

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