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Rhinocerebral Mucormycosis: A Review of 32 Cases In Mosul

Authors: Abdul Muhsen Younis Saleem --- Ajib Ali Moho --- Muna Muneer --- Emad Khalil
Journal: Medical Journal of Babylon مجلة بابل الطبية ISSN: 1812156X 23126760 Year: 2016 Volume: 13 Issue: 2 Pages: 366 -369
Publisher: Babylon University جامعة بابل

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Abstract

The aim of the present study is to evaluate the effectiveness of oral systemic antifungal (fluconazol) with nasal antifungal wash and aggressive surgical debridement in treatment of rhinocerebral mucormycosis. In a prospective hospital based study, we reviewed the management of 32 patients with rhinocerebral mucormycosis in Mosul general hospital and Al-Rahma Hospital (Mosul_Iraq), over a period of 7 years (Jan 1995 - Dec 2001). Diabetes mellitus was the main underlying cause in our patients and the main causative agent was mucor sp..The mortality rate was 56.2%. In Conclusion management of patients with rhinocerebral mucormycosis by oral antifungal (fluconazol) with nasal antifungal wash by mixture of clotrimazol and 20% sodium bicarbonate solution and aggressive surgical debridement after the control of the underlying disease, seems to be effective.

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