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Article
Effects of Oral Hypoglycemic Drugs on Flow Rate and Protein Composition of Saliva in Patients with Diabetes Mellitus

Author: Fayhaa AM Al- Mashhadane
Journal: Al-Rafidain Dental Journal مجلة الرافدين لطب الأسنان ISSN: 18121217 Year: 2011 Volume: 11 Issue: 18 Pages: 297-302
Publisher: Mosul University جامعة الموصل

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Abstract

Aims: To study the effects of both diabetes mellitus and oral hypoglycemic drugs (metfomin) on sali-vary flow rate and total protein levels of saliva and to compare them with control healthy subjects and to determine their effects on oral health of these patients. Materials and Methods: This study was carried out on 45 individuals (27 males and 18 females); 15 individuals of them were healthy subjects and considered as control group. The second group which comprised 15 patients with diabetes mellitus and received no any treatment (uncontrolled).The third group, diabetic patients were treated with met-formin only. Subjects were selected from the out patients attending Oral Surgery Department, College of Dentistry-University of Mosul. The samples of saliva were collected and salivary flow rates and total protein was determined for each individual, then its relation to oral health was measured accord-ing to Simplified Oral Hygiene Index by Greene and Vermillion. Results: One way analysis of variance was performed and showed that their were significant differences among all study groups for both sali-vary flow rate and total salivary protein concentration .The results of Duncan's Multiple analysis range test showed that there were no significant differences in salivary flow rates and total salivary protein concentrations between first and third groups while significant differences were seen between first and second and between second and third groups .For oral health scores , there was no significant differ-ences between first and third groups while significant differences were observed between first and se-cond and between second and third groups. Conclusions: Changes in salivary flow rates and salivary protein concentrations can result from diabetes mellitus which can affect oral health of these patients, while oral hypoglycemic drugs had no such effects

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Article
Effects of Cefepime Versus Doxycycline on Alveolar Bone Loss and Gingival Re-cession in Smoker Dental Patients: Clinical Trial

Author: Fayhaa AM Al-Mashhadane
Journal: Al-Rafidain Dental Journal مجلة الرافدين لطب الأسنان ISSN: 18121217 Year: 2011 Volume: 11 Issue: 17 Pages: 131-138
Publisher: Mosul University جامعة الموصل

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Abstract

Aims: To determine the prevalence and severity of attachment loss and bone loss among smokers and to compare them with non smokers and to assess the effect of cefepime compared to doxycycline in the outcomes of healing of these periodontal diseases in smoker patients. Materials and Methods: This study was carried out on 80 patients, half of which were smokers(40) and the other were nonsmokers, aged from 20 – 50 years, attending the teaching dental clinics in the College of Dentistry, University of Mosul. Questionnaire of smoking habit was applied on smoker patients. Clinical measurements were done including attachment loss and carried out according to Ramfjord gingival sulcus measurement index, Bone loss was measured radiographically with an x – ray unit. A total of 40 smoker patients were received supportive periodontal therapy and then randomly divided into 2 groups, first group (20 patients) were treated by cefepime powder mixed with distilled water and second group (20 patients) were treated by doxycycline powder mixed with distilled water. Both drugs were injected into peri-odontal pocket and remained in the oral cavity for 15 min then rinsed with distilled water. Each patient receive one session of treatment / once a week for 6 months. Clinical and ragiographical parameters of attachment and bone loss were measured at baseline , 2, 4 and 6 months recall visits. Results: Un-paired t – test was used for statistical analysis of the data and there were significant differences of at-tachment loss (p&#8804; 0.000) and bone loss (p&#8804; 0.001) between smoker and non smokers . There were no significant differences between smokers treated with cefepime compared to those treated by doxycyc-line for attachment loss (before treatment p&#8804;0.893, after treatment p< 0.668) and for bone loss (before treatment p<1.000, after treatment p< 0.849). Conclusions: Tobacco use is an important variable af-fecting the health of periodontal tissues. Topical application of antimicrobial agents at the site of peri-odontal diseases may be a useful adjunct to the conventional periodontal treatment.

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Article
The Clinical Effect of Phenytoin on Oral Wound

Author: Fayhaa AM Al- Mashhadane
Journal: Al-Rafidain Dental Journal مجلة الرافدين لطب الأسنان ISSN: 18121217 Year: 2012 Volume: 12 Issue: 19 Pages: 165-170
Publisher: Mosul University جامعة الموصل

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Abstract

Aims: To study the effect of oral phenytoin on healing of oral wound in buccal mucosa of rab-bits.Materials and Methods: This study was carried out on twenty healthy male rabbits weighing be-tween 1.0 – 1.5 Kg, they were divided into 2 groups; first group consisted of 10 untreated rabbits (con-trol) and second group consisted of 10 rabbits treated by phenytoin at dose of 60 mg/Kg orally along with 3 ml/Kg of sterile water using cavage needle for 10 days. All animals were anesthetized with amixture of xylazine hydrochloride and ketamine hydrochloride at 0.5, 50 mg/Kg intramuscular respec-tively, then a standard wound was made on buccal mucosa of each rabbit, all animals were kept under observation, and their wounds was measured every day with respect to surface area (length x width) in cm2, type of wound tissue and duration of healing. Results: t – test analysis was performed to test the differences in wound characteristics of both groups, it was found that there was significant differences between control and treatment groups (p< 0.001). Conclusions: Systemic use of phenytoin can delay oral wound healing of buccal mucosa.


Article
Tea Tree Oil: Anew Antifungal Agents Against Candida Albicans Cells on Heat–Cured Acrylic Resin Denture Base Material. An in vitro study

Author: Fayhaa AM Al–Mashhadane
Journal: Al-Rafidain Dental Journal مجلة الرافدين لطب الأسنان ISSN: 18121217 Year: 2007 Volume: 7 Issue: SpIss Pages: S54-S57
Publisher: Mosul University جامعة الموصل

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Abstract

Aims: In this research, the antifungal effect of tea tree oil on Candida that colonizes the heat cured acrylic resin denture base material was evaluated. Materials and Methods: In this clinical trial, 24 patients wearing upper complete dentures for more than one year were selected randomly from patients who were attending private dental clinics at Mosul city. Swabs from inner surface of upper complete dentures were taken for each patient then Candida albican were isolated, after that these dentures were immersed in the antifungal drugs (tea tree oil solution 15% and fluconazole solution 64 µg/ml) at 24 h and 48 hr. After that another swap was taken for each sample of complete denture to determine the antifungal effects of these agents. Results: The results of this study revealed that tea tree oil solution 15% and fluconazole solution 64 µg/ml had a significant antifungal effects, although tea tree solution effect was significantly less than fluconazole effects compared to control group [Candida albican culture (before immersion)]. Conclusions: The use of therapeutically active compounds extracted from plants like tea tree oil will offers a natural alternative with excellent antifungal effect and can be employed to reduce number of Candida albicans cells including those adhered to acrylic denture base material. This approach to fungal control is believed to be a practical for home care of dentures.


Article
The Effects of Ginger, Diazepam and Metoclopramide in Patients Receiving Dental Treatment

Authors: Mohammad A Mohi–Al Deen --- Fayhaa AM Al – Mashhadane
Journal: Al-Rafidain Dental Journal مجلة الرافدين لطب الأسنان ISSN: 18121217 Year: 2010 Volume: 10 Issue: 16 Pages: 358-365
Publisher: Mosul University جامعة الموصل

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Abstract

Aims: To diagnose and treat patients with gagging reflex during dental treatment and to compare ef-fects of ginger, diazepam and metoclopramide as different treatment modalities. Materials and Me-thods: This study was carried out on 120 dental patients, 37 males and 83 females who they are suffer-ing from moderate to severe gag reflex, their ages was ranged between 31 – 68 years old. The sample is randomly subdivided into 4 groups, each group consist of 30 patients, they was received different treatments (ginger, diazepam, metoclopramide and glucose (placebo)). Severity of gag reflex before and after treatments is reported depending on patient's words and direct reaction. Results: Kruskal – Wallis test was used to compare the response to treatment in 4 groups and there was significant differ-ences between them (p&#8804; 0.00). Conclusion: Ginger is effective antiemetic agent and can be useful for reducing nausea and vomiting (gag reflex) during and after dental treatment.

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Article
Salivary Protein Components and Oral Health in Patients Undergoing Therapy with Beta Adrenegic Agonist and Antagonist

Authors: Amer Taqa --- Fayhaa AM Al-Mashhadane --- Tahani A Al–Sandook
Journal: Al-Rafidain Dental Journal مجلة الرافدين لطب الأسنان ISSN: 18121217 Year: 2008 Volume: 8 Issue: 12 Pages: 219-224
Publisher: Mosul University جامعة الموصل

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Abstract

Aims: To study the effect of Beta–adrenergic agonist (salbutamol) and Beta adrenergic antagonist (atenolol) on salivary protein concentration and to study relation between salivary protein concentrationand oral health. Materials and Methods: This study was carried out on 45 individuals; 15 individuals of them were apparently healthy with no history of systemic diseases and represent a control group, thesecond group which comprised 15 subjects were given adrenergic agonist drug (salbutamol) for treatment of asthma, and third group (15 individuals) were given adrenegic antagonist drug (atenolol) fortreatment of hypertension. subjects were selected from the out patients attending Oral Surgery Department, College of Dentistry, University of Mosul. The samples of saliva were collected using spittingmethod and oral hygiene index simplified was recorded for each individual and total protein concentration of these saliva samples were determined. Its relation to oral health was measured accordingto simplified oral hygiene index by Greene and Vermillion. Results: The results of this study revealed that in all study groups, significant differences were present for both salivary protein concentration andoral health scores and there is correlation between salivary protein concentration and oral health in patients receiving atenolol. Conclusions: Chronic treatment with adrenergic agonist and antagonist drugs, resulted in changes in salivary protein concentration and those will affect the oral health of patients treated by these drugs.

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