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Article
Treatment of Tinea Capitis by Calvatia Craniformis Mushroom Powder

Author: Ghassan H. Jameel
Journal: Al-Mustansiriyah Journal of Science مجلة علوم المستنصرية ISSN: 1814635X Year: 2012 Volume: 23 Issue: 7 Pages: 41-48
Publisher: Al-Mustansyriah University الجامعة المستنصرية

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Abstract

Tinea capitis or scalp ringworm is a superficial fungal infection caused by Trichophyton and Microsporum genera . It is transmitted by humans, animals , or objects that harbor the fungus . The pathogenic fungus has rooted itself in the skin result in severe itching of the scalp , dandruff , and bald patches. Powder of some soil fungi named Calvatia craniformis mushroom is used after mixing with Vaseline in treatment of tinea capitis in human being , so the chemical compounds which present in this mushroom reveals high efficiency in killing the causative agent of the disease. Both concentrations were showed excellent activity against the isolates and reveals clear improvement compared to control group. Key words : tinea capitis , Calvatia craniformis.

يعد داء القرع في فروة الرأس Tinea capitis أو داء السعفة من الأمراض الفطرية السطحية التي تتسبب بجنسين من الفطور Trichophyton وMicrosporum ،إذ ينتقل المرض بواسطة الأشخاص المصابين والحيوانات والأدوات الملوثة التي تأوي الفطر المسبب. يتسبب هذان الجنسان بأحداث حكة شديدة في فروة الرأس مع قشور وبقع صلع وذلك لأن للفطر القدرة على اختراق الجلد.أستخدم مسحوق احد فطور التربة النوع Calvatia craniformis بعد خلطه مع الفازلين في علاج داء السعفة التي تصيب الإنسان إذ أظهرت المركبات الكيماوية المتواجدة في هذا الفطر كفاءة عالية في القضاء على المسبب المرضي وكان واضحآ عند شفاء الآفة المرضية في وقت مقارب للفترة الزمنية لشفاء المرضى في مجموعة السيطرة.

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Article
Comparative Treatment of Scaly Face (Mange) Mites in Budgerigars (Melopsittacus undulatus) by ointment prepared from Calvatia craniiformis mushroom powder with Promectine
مقارنة علاج حلم الوجه القشري (الجرب) في طيور الحب Melopsittacus undulatus بالمرهم المحضر من مسحوق الفطر Calvatia craniformis و promectin

Author: Ghassan H. Jameel غسان حمدان جميل
Journal: Diyala Journal For Pure Science مجلة ديالى للعلوم الصرفة ISSN: 83732222 25189255 Year: 2016 Volume: 12 Issue: 4 - part 1 Pages: 70-82
Publisher: Diyala University جامعة ديالى

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Abstract

In this study, thirty Budgerigars (Melopsittacus undulatus) with Knemidocoptes pilae infection were treated with three ointments in different concentrations prepared from Calvatia craniiformis mushroom in comparison with common antiparasitic drug promectine locally. Each concentration (0.12.5, 0. 25 and 0.5)% was applied to 5 Budgerigars from the first group each 72 hours at 12 days intervals. Also the promectine was injected subcutaneously twice to 15 Budgerigars(second group) at 12 intervals. Clinical signs in all birds of both groups disappeared at 13-35 days after treatment. The 0.5% was significantly different at (p <0.05) from other concentrations when compared with promectine. No side effects were seen.

عولج ثلاثون طير حب Budgerigars من النوع Melopsittacus undulatus في هذه الدراسة كانت مصابة بالنوع Knemidocoptes pilae المسبب للجرب بثلاثة تراكيز تم تحضيرها من الفطر Calvatia craniiformis موضعيآ بالمقارنة مع عقار البرومكتين promectin الشائع أستخدامه في علاج الطفيليات. أضيف كل تركيز %( 0.5, 0. 25, 0.12.5) موضعيآ لخمسة طيور من المجموعة الأولى كل 72 ساعة لفترة 12 يوم. كذلك أن طيور المجموعة الثانية البالغة 15 حقنت بالبرومكتين تحت الجلد مرتين خلال فترة 12 يوم. أختفت الأعراض السريرية من طيور كلا المجموعتينبعد أعطاء العلاج بفترة 13-35 يوم. كان التركيز 0.5% مختلف معنويآ (p <0.05) عن باقي التراكيز عند مقارنته مع البرومكتين . لم يلاحظ أي تأثيرات جانبية.


Article
Study of Ivermectin effect on the bovine warts

Authors: Thekra A . Ebraheem --- Saba J . Jawad --- Ghassan H . Jameel
Journal: Diyala Journal For Pure Science مجلة ديالى للعلوم الصرفة ISSN: 83732222 25189255 Year: 2011 Volume: 7 Issue: 2 Pages: 117-126
Publisher: Diyala University جامعة ديالى

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Abstract

Cutuneous warts in bovine are benign tumors induced by virus belongs to
papillomaviruses family . Ivermectin drug used in treatment of endo and ectoparasites in
animals and to treat the bovine warts at a dose 300 microgroms / Kg . B . wt . sub
cutaneously .
Ten cattles were be used in this expirement , five of them injected subcutaneously at
the base of the wart and other Five injected also subcutaneously upper of the scapular bone
faraway the wart position .
Statistical analysis for obtained results reveals presence of singnificantly raised
(P<0.05)in the mean of total white blood cells count from (5.480±1.064)cell before treatment
and reach to (7.380±0.511)cell after treatment and the mean of lymphocytes rate from
(35.200±6.685)% before treatment and reach to (65.400±11.929) %after treatment .Also
reveals significant depression (P<0.05) in the mean of neutrophils and monocytes rates from
(57.800±6.685)% , (4.200±0.836)% before treatment and reach to (31.200±11.322)% , (1.600
± 1.140)% after treatment respectively .
Eight cattles were being recover from sum of ten cattles and the clearance rate reach's
to 80% without any side effect on the animals so the mean of total white blood cells counts
for recovered animals are showing in table -1 are being normal was (5.940±0.698) also the
mean of differential percentage of the white blood cells is returned normal , neutrophils was
(60.400±0.270)% , lymphocytes (33.600+3.209)% , monocytes (4.400±0.894)% , eosinophils
(1.200±0. 447)% ,and basophils (0.600±0.548)% .


Article
IVERMECTIN ACTIVITY IN TREATMENT OF CATTLE DERMATOPYHTOSIS.

Authors: Ghassan H. Jameel --- Amjad A. Ahmed --- Osama K. Jalil --- Wedad S. Dawood
Journal: Diyala Journal of Agricultural Sciences مجلة ديالى للعلوم الزراعية ISSN: 20739524 Year: 2015 Volume: 7 Issue: 1 Pages: 30-40
Publisher: Diyala University جامعة ديالى

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Abstract

In order to determine the dermatophytosis infection in cattle, twentyscraping samples were collected from cattle showed clinical signs of skindisease in different areas in Diyala governorate during a period fromNovember 2012 to May 2013.Results in cattle samples showed that 18 out of 20(90%) were positive forfungal infection. The highest percentage of infection was seen in November(50%), (30%) in February, and the lowest in March (20%). The main fungalspecies that isolated was Trichophyton verrucosum. A single subcutaneousinjection of ivermectin at a dose of 200 microgram/kg. was administered tothe affected animals. Recovery was observed after 10 days after injection,started by scales dropping and appearance of the hair. These findings showthat ivermectin can be used successfully in the treatment of dermatophytosisin bovine induced by immunopotentiation due to the elevation in the totalwhite blood cells ( lymphocytes) after ivermectin injection.


Article
COPARISON OF THE EFFECT OF CALVATIA CRANIFORMIS MUSHROOM EXTRACT WITH SOME COMMON ANTIBIOTICS USED IN TREATMENT OF BACTERIAL ENDOMETRITIS IN WOMEN OF BAQUBACITY AND IT’S PERIPHERIES.
مقارنة تأثير مستخلص الفطر Calvatia craniformis مع بعض المضادات الحياتية شائعة الاستعمال في علاج البكتريا المسببة لالتهاب بطانة الرحم في نساء مدينة بعقوبة وضواحيها .

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Abstract

Sixty samples of vaginal secretions were be collected from women attending the health care centers in Baquba city center and it's peripheries for the time period January 2010 to May 2011.Culturing of bacterial samples revealed six isolates for Staphylococcus aureus and twenty four isolates for Escherichia coli and three isolates for Lactobacillus Spp.The effect of the following concentrations (10,15) % Which were prepared from the Calvatia craniformis mushroom were active against the S. aureus while the concentrations (5,10)% were inactive against the E. coli , but the concentration 15% was be active against E. coli .The three concentrations showed non significant effect on killing the Lactobacillus. The statistical analysis revealed significant differance at (p < 0.05) between the effect of 15% concentration on the S.aureus and E.coli , so the diameter of inhibition zone was (1.3,1.5) Cm respectively when it is compared with the antibiotics such as ciprofloxacin and trimethoprim , but no significant correlation revealed with effective drugs on Lactobacillus ..

جمعت (60)عينة لإفرازات مهبلية من نساء يراجعن مراكز الرعاية الصحية في مركز وأقضية ونواحي محافظة ديالى للفترة الزمنية كانون الثاني 2010 لغاية مايس لعام 2011 .أظهرت نتائج الزرع البكتيري للعينات بأن (6)عزلات كانت تعود إلى Staphylococcus aureus و(24)عزلة تعود إلى coli Escherichia و(3)عزلات تعود إلىLactobacillus .كان تاثيرالتركيزين (15 , 10)% المحضرين من مسحوق الفطر Calvatia craniformis ذا فعالية ضد Staphylococcus aureus، ولم يكن التركيزان (10 , 5)% فعالين ضد coli Escherichia ولكن التركيز 15% كان ذا فعالية ضد coli . Escherichiaأما التراكيز الثلاثة فلم يكن لها أهمية تذكر في القضاء على Lactobacillus .اظهر التحليل الإحصائي وجود فرق معنوي (p< 0.05) بين تأثير التركيز 15% على بكتريا المكورات العنقودية الذهبية والاشريكيا القولونية إذ بلغ قطر منطقة التثبيط (1.5 , 1.3)سنتيمتر على التوالي عند مقارنته مع تأثير الأدوية المستخدمة في العلاج مثل Ciprofloxacin و Trimethoprim ولم يظهر أي ارتباط معنوي مع الأدوية المؤثرة على بكتريا العصيات اللبنية.


Article
Treatment of Tinea Corporis by 0.50% Topical Ointment Prepared from Calvatia Craniformis Mushroom

Authors: Ghassan H. Jameel غسان جميل --- Azher S. Khamees ازهر خميس --- Wathik M.Al-shimary واثق الشمري --- Mahmood S. Rasheed محمد رشيد
Journal: Diyala Journal of Medicine مجلة ديالى الطبية ISSN: 97642219 Year: 2011 Volume: 1 Issue: 2 Pages: 1-5
Publisher: Diyala University جامعة ديالى

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Abstract

Background: Tinea Corporis or Ringworm is a fungal disease caused by Trichophyton rubrum,T.mentagrophytes , Microsporum canis andT.tonsurans.It is transmitted by direct contact with infected animals and humans or by indirect contact through fomites.The Aim of Study: This study aims to evaluate the efficacy of 0.50% ointment prepared from Calvatia craniformis mushroom in treatment of Tinea Corporis in human.The Patients and Methods : The study is done in dermatology clinic in Baquba city. Three different concentration of Calvatia craniformis mushroom ointment are prepared by mixing three different weights of mushroom powder (0.3 ,0.4 and 0.5gm) with vaseline and completed up to 100 gm for each concentration to obtain (0.3%,0.4% and 0.5%) of the mushroom ointment respectively and then applied topically to lesion twice daily. Sixty patients were involved in our study and divided into two groups, the treatment group includes thirty patients which is divided into three subgroups, each subgroup include ten patients they were treated by one of the three concentrations ( Ten patients 0.3% , Ten patients 0.4%, Ten patients 0.5% concentrations). The control group included thirty patients was treated by 1% clotrimazol cream. Results and Conclusion: 0.5% mushroom ointment significantly reduce clearance time (P<0.05)in comparison with the control group , while other concentration produce non significant changes in clearance time , therefore this substance is effective in the treatment of tinea corporis with less time, more patient compliance compared with the control group.

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Article
Treatment of Pityriasis versicolor by 2% solution of Copper sulfate
علاج داء السعفة المبرقشة Pityriasis versicolorباستخدام محلول 2%كبريتات النحاس

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Abstract

Pityriasis or Tinea versicolor is a skin fungal infection caused by a yeast type of skin fungus called Pityrosporum orbiculare . Mineral solution which is prepared from dissolution of copper sulfate powder in distil water in two concentration (1%,2%) is used in treatment of forty patients infected by pityriasis versicolor applied twice daily on infected site.Statistical analysis reveals the presence of significant correlation (p<0.05) in time of clearance of the lesion between the treated group by 2% concentration and control group which is treated by 1% clotrimazole were be 12 and 45 days respectively.The rate of cure was be 100% in all treated person who are completes the period of treatment by our preparation but in different periods.

يعد داء السعفة المبرقشة Pityriasis versicolor من الأمراض الجلدية الفطرية الذي يتسبب بأحد أنواع الفطور الجلدية الذي يسمى Pityrosporum orbiculare.تم استخدام المحلول المعدني المحضر من اذابة مسحوق كبريتات النحاس Copper Sulfate بالماء المقطر بالتركيزين (2%,1%) في علاج ستون شخصا أصيبوا بداء السعفة المبرقشة Pityriasis versicolor وذلك بمسح الآفة المرضية مرتين باليوم.أظهر التحليل الإحصائي للنتائج وجود ارتباط معنوي (p<0.05) بالفترة الزمنية لشفاء الآفة المرضية بين مجموعة العلاج بالتركيز 2% ومجموعة السيطرة المعالجة بمحلول 1% Clotrimazole إذ بلغت 12 و 45 يوم على التوالي.بلغت نسبة الشفاء 100% لكافة الأشخاص اللذين أكملوا فترة العلاج باستخدام مستحضرنا وبفترات زمنية مختلفة


Article
EVALUATION OF Calvatia craniformis MUSHROOM ACTIVITY IN TREATMENT OF RINGWORM DISEASE IN CATTLE .
تقويم فاعلية الفطر Calvatia craniformis في عـلاج داء القوباء الحلقية Ringworm disease في الأبقار.

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Abstract

Calvatia craniformis mushroom is used in treatment of ringworm disease in cattle . The ringworm is zoonotic disease spread via direct contact with infected animal by Trichophyton verrucosum fungus.The preparations prepared from the powder extracted by crushing the fruiting body and mixed with Vaseline to obtain three concentrations (0.25,0.5,1) % . The results in this study reveal to the concentration 1% has sidle effect on the causing agent and this is reflected by periods of clearance which reach to ( 12,8) days when the preparation is applied without curettage to the lesion and when the curettage is done and preparation is applied respectively and when they are compared with other concentrations in two cases. The statistical analysis reveals presence of significant deference (P<0.05) in the period of clearance of the lesion when we are used our preparation 1% when is compared with 1% sulfur ointment .

أستخدم فطر Calvatia craniformis في علاج داء القوباء الحلقية Ringworm disease في الأبقار والذي يعد من الإمراض المشتركة بين الإنسان والحيوان و ينتقل بالتماس المباشر مع الحيوان المصاب بالفطر Trichophyton verrucosum . تم تحضير ثلاثة مستحضرات حاوية على المسحوق المستخلص من عملية سحق مكونات الجسم الثمري للفطر الجاف وخلطه مع الفازلين للحصول على ثلاثة تراكيز (0.25 ، 0.5 ، 1) % بعد نخل المسحوق وتنقيته من الشوائب بدون إجراء أي عمليات استخلاص كيمائية لمكونات الفطر الطبيعية . أظهرت نتائج الدراسة الحالية بان تركيز المستحضر البالغ 1% كان اكثر فاعلية في القضاء على العامل المسبب للمرض ويظهر ذلك جليا من مدتي الشفاء البالغتين(8,12) يوم عند وضع المستحضر بدون حك الآفة المرضية ، وعند حك الآفة ثم وضع المستحضر على التوالي إذا ما قورنت مع التراكيز الأخرى في كلتا الحالتين .أظهر التحليل الاحصائي وجود فرق معنوي (P<0.05) بالفترة الزمنية للشفاء عند استخدام مستحضرنا بالتركيز 1% عند مقارنته بمرهم الكبـريت بتركيز1% .

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