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Article
Prevalence of Hypertension in Deep and Lobar Intracerebral Hemorrhage in a Group of Iraqi Patients

Author: Hasan A. Al-Hamadani حسن عزيز الحمداني
Journal: Journal of the Faculty of Medicine مجلة كلية الطب ISSN: 00419419 Year: 2013 Volume: 55 Issue: 2 Pages: 102-105
Publisher: Baghdad University جامعة بغداد

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Abstract

Background: Non-traumatic Intracerebral Hemorrhage (ICH) results from rupture of blood vessels in the brain. ICH categories can also be considered as being either lobar in location or within the deep white matter. Although hypertension is a major risk factor for ICH in general[11], it is commonly considered to be associated more with patients having deep than with those having lobar haemorrhage.Objectives: We investigate the relationship between hypertension and deep versus lobar intracerebral hemorrhage (ICH).Methods: a retrospective review of records of 163 patients aged 18-89 years admitted to Al-Kadhimiya Teaching Hospital (January 2008 - October 2010) and diagnosed with ICH.Results: There was no significant relationship between hypertension in deep versus lobar intracerebral hemorrhage (p=0.814)Conclusions: Although the relation between hypertension and ICH was not found to be significant, our study suggests and recommends age-appropriate investigations for patients with ICH, as well as the need to promote patients’ education with regards to this disease and the importance of adherence to treatment of risk factors. Key words: Hypertension, Intracerebral and Hemorrhage


Article
clinical prognostic factors after the first attack of early onset multiple sclerosis in iraq
العلامات السريرية التنبأية بعد الانتكاسة الاولى لمرض تصلب الاعصاب المنتشر المبكر الحدوث في العراق

Author: Hasan A.Al hamadani حسن عزيز الحمداني
Journal: Journal of the Faculty of Medicine مجلة كلية الطب ISSN: 00419419 Year: 2011 Volume: 53 Issue: 4 Pages: 358-362
Publisher: Baghdad University جامعة بغداد

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Article
THE RELATION OF HYPOKALEMIA TO HYPERTENSIVE AND NON-HYPERTENSIVE ISCHEMIC STROKE

Authors: Haider A. Husain حيدر علي حسين --- Hasan A. Al-Hamadani حسن عزيز الحمداني --- Munther T. Hamzah منذر طاهر حمزة
Journal: IRAQI JOURNAL OF MEDICAL SCIENCES المجلة العراقية للعلوم الطبية ISSN: P16816579,E22244719 Year: 2014 Volume: 12 Issue: 2 Pages: 102-107
Publisher: Al-Nahrain University جامعة النهرين

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Abstract

Background:Several clinical and laboratory observations are consistent with the hypothesis that hypokalemia might be a risk factor for the development of ischemic stroke in humans.Objectives:To evaluate the level of serum potassium in ischemic stroke patients and its relation to non-stroke patients and those with hypertension.Methods:Serum potassium was estimated from one hundred newly discovered first-life ischemic event of acute ischemic stroke patients and one hundred control patients with an attempt to evaluate the its level in ischemic stroke and the relation to hypertension. Normal value of serum potassium in both sexes was considered as 3.5-.5.5 mmol/L.Results:Mean serum potassium level of stroke patients was significantly lower than that of control group (3.89±0.67 versus 4.19±0.56, p=0.0001). Hypokalemia was found in 23 (23%) patients with stroke compared to 7 (7%) of the control group. The Mean serum potassium in hypertensive patients was significantly lower than those without hypertension (3.91 ±0.65 versus 4.2 ±0.54). The mean serum potassium for hypertensive stroke patients was significantly lower than non-hypertensive stroke patients (3.79±0.78 versus 4.26±0.72), while there was no significant difference among the control hypertensive and non-hypertensive subjects (4.05±0.57 versus 4.43±.40).Conclusions:Serum potassium should be taken in consideration as low levels are significantly associated with ischemic stroke with hypertension.Keywords:Serum Potassium, ischemic stroke


Article
BELL'S PALSY: EVALUATION OF CLINICAL RESPONSE TO MEDICAL TREATMENT

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Abstract

Background:Corticosteroid and antiviral agents are widely used to treat the acute phase of Bell's palsy but their effectiveness is still uncertain.Objective:This study aimed to compare the theraputic effect of Acyclovir and steroid versus steroid alone, in combanation with physiotherapy, in patients with Bell's palsy.Methods:This interventional study was conducted in Al-Yarmok Teaching Hospital and Al-Kadhimiya Teaching Hospital, during the period from July 2007 to July 2008. It involved (58) patients, who were divided into two groups: Group A; 28 patients, treated by steroid for 10 days. Group B; 30 patients, treated by steroid and acyclovir for 10 days. Physiotherapy for one month for both groups was followed and reassessment according to House-Brackmann grading system was done after completion of each therapy.Results:The recovery of patients treated with steroid and Acyclovir was (66.6%), while the patients treated with steroid alone was (46.4%), however, the diffrence was statistically insignificant. After one month physiotherapy the responses were (76.7% and 53.5%) for patients in both groups respectively.Conclusion:The addition of Acyclovir therapy in Bell's palsy has not found to be benefitial.Keywords:Bell's palsy, Corticosteroid, Antiviral agents, Physiotherapy.


Article
ANTIPHOSPHOLIPID ANTIBODY IN SERUM OF GUILLAIN-BARRE SYNDROME PATIENTS

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Abstract

Background: Studies have provided convincing evidence that Guillain-Barre syndrome [GBS] is caused by an infection-induced aberrant immune response that damages peripheral nerves. Despite intensive research over the past two decades, the immune target is still unknown in patients with acute inflammatory demyelinating polyradiculoneuropathy [AIDP], the most frequent variant of GBS.Objective: Measuring of immunoglobulin G [IgG] and immunoglobulin M [IgM] antiphospholipid antibodies [aPL] of incidental untreated GBS patients and comparing them with that of normal population.Methods: This is an age and gender matched paired case-control study at Al-Kadhimiya Teaching Hospital between 1-Dec-2008 and 31-Jan-2010. Each patient was paired with the age and sex matched control which was useful in controlling the confounding effect of age and gender on possible case-control differences. The aPL were measured by Immunometric Enzyme Immunoassay.Results: Eleven patients with GBS (cases) and eleven age and gender matched controls included in current study. The GBS cases have higher IgM and IgGaPL titers than healthy controls [P=0.026, P=0.13 respectively]. The GBS cases IgMaPL titers have negative correlation with duration of illness [r=-0.494, P=0.12], while the cases IgGaPL titer have positive correlation with duration of illness [r=0.243, P=0.47]. The GBS cases that need mechanical ventilation have lower IgM and IgGaPL titers than cases that do not need mechanical ventilation [P=0.1, P=0.06 respectively].Conclusion: GBS cases have statistically significant higher IgMaPL titers during the first week [p=0.028] and the first two weeks [p=0.026]of illness than healthy controls, and aPL may have a protective effect in GBS.Keywords: Guillain-Barre syndrome, Demyelination, Antiphospholipid antibodies and autoantibodies.

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