research centers


Search results: Found 3

Listing 1 - 3 of 3
Sort by

Article
Isolation and identification of oral candida spp. from leukemic children under chemotherapy and treatment with extraction of different plants in vitro

Author: Heba F. Hassan هبة حسن
Journal: Journal of baghdad college of dentistry مجلة كلية طب الاسنان بغداد ISSN: 16800087 Year: 2012 Volume: 24 Issue: 4 Pages: 152-156
Publisher: Baghdad University جامعة بغداد

Loading...
Loading...
Abstract

Background: Oral candidiasis represents a serious problem for children with cancer during chemotherapy. The aim ofthis study was isolation and identification of oral candida spp.Materials and method: Sixty five oral swabs were taken from children suffering from leukemia.Results and Conclusion: The results of isolation in this research showed prevalence of candida.albicans at 64.62 %and C.glabrata 20%. In vitro antifungal activity of aqueous of (Quercus infectoria , Cinnamon , punica Granatum) atconcentration 100-500mg/ml against ( C. albicans, C.glabrata, C.tropicalis and C .famata ) showed the Quercusinfectoria was more active against ( C. albicans, C.glabrata, C.tropicalis and C .famata ) compared with othersplants extracts which used in this study.


Article
Mitotic activity of cultured human lymphocytes treated with gold nanoparticles

Authors: Sumaiah I. Hussein --- Yahya D. Saihood --- Ayda M. Majeed --- Heba F. Hassan --- et al.
Journal: Iraqi Journal of Cancer and Medical Genetics المجلة العراقية للسرطان والوراثة الطبية ISSN: 20786123 Year: 2017 Volume: 10 Issue: 2 Pages: 212-215
Publisher: Al-Mustansyriah University الجامعة المستنصرية

Loading...
Loading...
Abstract

Potential health and environmental effects of nanoparticles need to be thoroughly assessed before their widespread commercialization.The present investigation was planned with the aims to determine the effects of gold nanoparticles (GNPs) onblast (BI) and mitotic (MI) indices of cultured lymphocytes. The results revealed that BI (50.3 ± 2.3, 30.2 ± 1.9, 10.5 ± 0.7 and0.0%, respectively) and MI (70.1 ± 2.9, 20.4 ± 1.1, 5.3 ± 0.1 and 0.0%, respectively) showed a gradual decreased percentageas the concentration of GNPs was increased from 0.085 to 0.66 μg/mL, and the difference was significant compared to controlculture (81.6 ± 2.5 and 90.2 ± 3.7%, respectively). A maximum inhibition of BI and MI was occurred at the concentration 0.66μg/mL. In conclusion, GNPs can be considered as a growth inhibiting agent, but it is too early to reach a final conclusion inthis regard and further investigations are required to elucidate the biochemical mechanisms involved in inhibiting the mitoticactivity of lymphocytes.


Article
DETECTION OF HEPATITIS C VIRUS IN IRAQI PATIENTS WITH ORAL LICHEN PLANUS

Loading...
Loading...
Abstract

Background:Oral Lichen planus (OLP) is chronic mucocutaneous disorder with or without involvement skin, of unknown etiology. Lichen planus (LP) is T-cell-mediated chronic inflammatory disease of the stratified squamous epithelium. It can affect oral mucosa, skin, esophagus, nasal mucosa, larynx, genitalia, urinary tract, hair follicles and the eyes. Latterly has been focused on presence association between OLP and hepatitis C virus (HCV) infection, but this relation is not stable, since the prevalence of this virus in patients varies depended on studies, ranging from 0% to 67.8%. Objective:This study was established to investigate the relationship between the OLP and HCV infection in Iraq and to detect the virus by Real-time polymerase chain reaction (RT-PCR).Methods:Blood samples were collected from 62 patients with OLP and controls to detect the HCV in those patients by using one step anti-HCV test, ELISA test and RT-PCR.Results:The current study revealed that the early detection of HCV by one step Anti-HCV for all OLP patients was negative and by ELISA showed that four patients (12.5%) of OLP were positive for HCV. While using RT-PCR found that only one patient (3.1%) was positive for the presence of the virus.Conclusion:There was not relationship found between OLP and HCV infection in Iraqi patients.Keywords:Oral lichen planus, HCV, RT-PCR, ELISA

Keywords

Oral lichen planus --- HCV --- RT-PCR --- ELISA

Listing 1 - 3 of 3
Sort by
Narrow your search

Resource type

article (3)


Language

English (3)


Year
From To Submit

2017 (1)

2016 (1)

2012 (1)