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Article
The frequency of penile acne among Iraqi males with facial acne vulgaris

Author: Husam A. Salman
Journal: Journal of the Faculty of Medicine مجلة كلية الطب ISSN: 00419419 / 24108057 Year: 2008 Volume: 50 Issue: 4 Pages: 445-447
Publisher: Baghdad University جامعة بغداد

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Abstract

Background: Acne vulgaris is a common skin problem. It affects areas of high density of sebaceous glands like the face, chest and back. The penile skin is no exception, also can be affected with acne, however little was written on this subject.
Patients & Methods: This is a clinical epidemiological study conducted at the Department of Dermatology & Venereology- Baghdad Teaching Hospital, during the period between December 2007 and May 2008. Seventy six male patients with facial acne vulgaris were enrolled in the study. A full history includes age, age of onset of facial acne and any penile lesion observed by the patient Examination of the face was done for the severity of acne and grading it into mild, moderate, severe and very severe according to Allen and Smith method. The penis of each patient was examined for the presence of ectopic sebaceous glands and acne.
Results: A total number of 76 patients, their ages ranged between13 - 30 years with mean + 19.033 + 4.609. They were classified into 4 groups according to the grades of severity of acne vulgaris, 23 (30.26%), 20 (26.31%), 18 (23.68%) and 15 (19.73%) corresponding to mild, moderate, severe and very severe respectively. The frequency of ectopic sebaceous glands in these 4 groups were 15(65.21%),14(70%), 12(66.66%) and 9(60%) respectively with a total 65.78 % from all patients with facial acne. The frequency of penile acne in these 4groupswere4 (17.39%),3(15%),3(16.66%) and 2 (13.33%) with a total 15.87 % from all patients with facial acne. There was neither a statistical significant difference in the frequency of penile ectopic sebaceous glands nor of penile acne among the 4 grades of facial acne vulgaris. P value = 0.993 and 0.992 respectively. In all patients the ectopic sebaceous glands and lesions of penile acne were situated in the ventral surface of the penis. Most patients who were aware about penile lesions and afraid from having sexually transmitted disease were those having papules and pustules.Conclusion: Penile ectopic sebaceous glands were a common skin condition and penile acne was not uncommon skin problem among Iraqi males.


Article
Chronic ulcerative Cutaneous Vasculitis of the legs Clinical and histopathological study

Authors: Husam A. Salman --- Hayder R. Al-Hamamy --- Thamir A. Hamed
Journal: Journal of the Faculty of Medicine مجلة كلية الطب ISSN: 00419419 / 24108057 Year: 2009 Volume: 51 Issue: 1 Pages: 34-38
Publisher: Baghdad University جامعة بغداد

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Abstract

Background: Cutaneous small vessel vasculitis characterized by necrosis and inflammation of upper dermal blood vessels. It presents with ulcers and systemic manifestations after extensive acute onset. Many patients have a form of cutaneous vasculitis that presents with chronic painful ulcerations & purpuras involving the ankles without systemic manifestations, with some similarity in clinical presentation to livedoid vasculopathy. Patients and Methods: Thirteen patients were seen in the Department of Dermatology and Venereology, Baghdad Teaching Hospital, for a period extending from January 2004 to March 2005. They were evaluated clinically, histopathologically and other laboratory studies. In addition, evaluation of the clinical response to prednisolone 0.5mg/kg/day and azathioprine150mg/day was done.
Results: Thirteen patients were included in this study; eight females and five males, with male to female ratio of 1:1.6. Their ages ranged between 26-66 years with a mean ±SD of 42 ± 13.8 years. The duration of the disease ranged from 0.5 – 18 years with a mean ±SD of 38 ± 59.2 months.The clinical examination revealed multiple oval punched out ulcers, with an indurated base, and surrounded by a zone of erythema; affecting mainly the ankles and dorsa of feet. Histopathological evaluation showed upper dermal vessels' wall necrosis, fibrinoid deposition, obliteration of the lumen, extravasation of red blood cells, endothelial cells swelling with perivascular and vascular wall infiltration mainly by mononuclear cells.The treatment was started with prednisolone & azathioprine. The ulcers healed completely with residual hyperpigmentation - hypopigmentation, atrophy and scars within 10-15 weeks Conclusions: Chronic ulcerative cutaneous vasculitis is often a neglected and misdiagnosed variant of vasulitis. Histologically it has vascuiltic features, and clinically looks like livedoid vasculopathy.


Article
Treatment of perniosis with oral tadalafil, pentoxifylline or prednisolone A therapeutic comparative study
علاج الشرث عن طريق الفم بالتادالافيل، البنتوكسيفيلين أو البردنيزولون دراسة علاجية موازنة

Authors: Adil A. Noaimi عادل عبد الغفور النعيمي --- Husam A. Salman حسام علي سلمان --- Khalifa E. sharquie خليفه عبيدالشرقي
Journal: Journal of the Faculty of Medicine مجلة كلية الطب ISSN: 00419419 / 24108057 Year: 2015 Volume: 57 Issue: 3 Pages: 210-213
Publisher: Baghdad University جامعة بغداد

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Abstract

Background: perniosis is a common dermatological problem. Different modalities of treatment are available with conflicting results and no single effective therapy is universally accepted. Objective: To evaluate the effectiveness of oral tadalafil and compare it with pentoxyfylline or prednisolone in treatment of perniosisPatients and methods: This was a therapeutic comparative trial conducted in the department of Dermatology, Baghdad Teaching hospital, Baghdad, Iraq between November 2011 and March 2014.Fifty eight patients with perniosis were enrolled in this study, and divided into 3 groups. Group (A) comprised 19 patients who received oral tadalafil (5 mg once daily); group (B) comprised 18 patients who received pentoxifylline tablet (400 mg three times daily) and group (C) included 21 patients who received prednisolone 15 mg twice daily. The treatment duration was 2 weeks. All patients did not receive any treatment before the study. A severity score was proposed taken in consideration the number of finger/ toes, type of lesion, coldness, cyanosis and itchingResults: Forty seven patients completed the study. Their ages ranged from 13-43 with a mean ± SD of 22.38 ±6.99 years. Thirty three patients were females (70.21%) and 14 were males (29.79%).The percentage of improvement was 50.65, 44.16 and 31.51% for the groups A, B and C respectively.Conclusion: Tadalafil has a superior effect over pentoxyfylline. The latter has a better effect than prednisolone. Key words: Tadalafil, pentoxifylline, prednisolone, perniosis, chilblains

الخلاصة: المقدمة: الشرث مشكلة جلدية شائعة. تتوفر أساليب مختلفة من العلاج مع نتائج متضاربة. لايوجد علاج فعال وحيد مقبول عالمياً.الهدف: لتقييم فعالية تادالافيل، وذلك مقارنة مع بينتوكسيفيليني أو البردنيزولون في علاج الشرثالمرضى والطرق: محاولة موازنة علاجية أجريت في قسم الأمراض الجلدية، مستشفى بغداد، بغداد، العراق، بين تشرين الثاني 2011، وآذار 2014.ثمانية وخمسون من مرضى الشرث مسجلين في هذه الدراسة، وتم تقسيمهم إلى 3 مجموعات. المجموعة (أ) تضم 19 من المرضى الذين تلقوا تادالافيل (5 ملغ مرة واحدة يوميا)؛ المجموعة (ب) تتالف من 18 من المرضى الذين تلقوا بنتوكسيفيلين (400 ملغ ثلاث مرات يوميا) والمجموعة (ج) وشملت 21 مريضا الذين تلقوا بردنيزولون 15 ملغ مرتين يوميا. وكانت مدة العلاج اسبوعين. جميع المرضى لم يتلق أي علاج قبل الدراسة. تم اقتراح طريقة جديدة لقياس شدة المرض أخذ في الاعتبار عدد الإصبع/أصابع القدم، نوع الآفة، وجود البرودة، الزرقة والحكة.النتائج: سبعة وأربعون مريضا إكمل الدراسة. أعمارهم تراوحت بين 13-43 سنة وبمعدا ± الانحراف المعياري 22.38 ±6.99 سنوات. كان المرضى ثلاثة وثلاثين من الإناث (70.21%) و 14 من الذكور (29.78 ٪).النسبة المئوية للتحسن كان 50.65، 44.16 و 31.51% للمجاميع ألف وباء وجيم على التواليالاستنتاج: تادالافيل له أثرا متفوق على مدى بينتوكسيفيليني. هذا الأخير له تأثير أفضل من البردنيزولون.مفاتيح الكلمات: تادالافيل، بنتوكسيفيلين، بردنيزولون، الشرث


Article
Axenic Procyclic Culture of L. tropica and L. donovani in Culture of FBS-free Medium
المزروع المختبري النقي لطفيلي اللشمانيا الجلديه والاحشائية في الوسط الزرعي الخالي من مصل جنين العجل

Authors: Fatema M. Mosa فاطمة محسن موسى --- Husam A. Salman حسام علي سلمان --- Hayder Z. Ali حيدر زهير علي
Journal: Iraqi Journal of Science المجلة العراقية للعلوم ISSN: 00672904/23121637 Year: 2015 Volume: 56 Issue: 4B Pages: 3088-3093
Publisher: Baghdad University جامعة بغداد

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Abstract

Leishmania causes disease ranging from self-healing cutaneous to fatal visceral leishmaniasis (VL). Leishmaniasis is reported endemic in 88 countries, including Iraq, in which 82% in low-income countries. The diseases develop following the bite of sand flies injecting Leishmania promastigotes into skin. Promastigotes transform into amastigotes in vivo multiplying within macrophages. In this study we have investigated the ability of axenic procyclic promastigotes of cutaneous Leishmania tropica and visceral Leishmania donovani survive in M199 media with or without Fetal Bovine Serum (FBS) added. Three time incubation periods were adopted (24, 48 and 72) hours and the results showed that L. tropica was able to survive and multiply in both FBS-medium and FBS-free medium, while L. donovani showed significant decrease in surviving in the FBS-free medium at day three of follow up. Such results may indicate the difference in Leishmania species requirements in growth culture in vitro.

طفيلي اللشمانيا يسبب داء اللشمانيات والذي يتراوح ما بين الشفاء الجلدي الذاتي لداء اللشمانيات الحشوي القاتل.تفيد التقارير ان داء اللشمانيات متوطن في 88 دولة من ضمنها العراق، ونسبة 82٪ من الإصابات في البلدان ذات الدخل المنخفض. داء اللشمانيات يتطور بعد نقل ذبابة الرمل للطور السوطي للشمانيا في الجلد.الطور السوطي يتحول إلى طور عديم السوط في المضيف الفقري ويتكاثر داخل البلاعم العملاقة. في هذه الدراسة قمنا بدراسة مقاومة الاشكال المسوطة خارج الجسم الحي للشمانيا الجلدية واللشمانيا الحشوية في الوسط الزرعيM199 بوجود او عدم وجود مصل البقر الجنيني (FBS). اذ اعتمدت ثلاثة أوقات للمتابعة (24, 48, 72) ساعة، وأظهرت النتائج أن اللشمانيا الجلدية كانت قادرة على البقاء على قيد الحياة والتكاثر بوجود او عدم وجود FBS على مدى أوقات المتابعة الثلاثة في حين أظهرت اللشمانيا الاحشائية القابلية على النمو و التكاثر في الوسط الزرعي المزود بال FBSبينما انحسرت قابليتها في اول يومين فقط في الوسط الزرعي الخالي من FBS اذ كان هناك انخفاض معنوي في تعداد الطفيلي في اليوم الثالث.تشير هذه النتائج الى وجود فروقات في متطلبات النمو لنوعي اللشمانيا الجلدي والحشوي في النمو في المختبر.

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