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Article
Biochemical Changes of Serum Liver Enzymes (Aspartate aminotransferase, Alanine aminotransferase and Alkaline phosphatase) in Cigarette Smokers in Mosul.
البيوكيميائية التغييرات انزيمات الكبد المصل (الأسبارتات aminotransferas

Author: Isra’a H .AL-Hamdani,
Journal: The Medical Journal of Tikrit مجلة تكريت الطبية ISSN: 16831813 Year: 2007 Volume: 2 Issue: 132 Pages: 161-165
Publisher: Tikrit University جامعة تكريت

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Abstract

Cigarette smoking cause many effects in human body. These effects can be studied by measurement of various biochemical parameters in the blood. In the present study (3) biochemical parameters (aspartate aminotransferase AST , alanine aminotransferase ALT ,and alkaline phosphatase ALP) had been measured in blood of 139 apparently healthy volunteers ,including 88 smokers ( 55 males and 33 females ) and 51 nonsmokers as a control group ,in order to investigate the effect of cigarette smoking on these liver enzymes , and comparison the mean enzymes activities between male and female smokers .It is found a significant increase of serum AST, ALT and ALP activity noticed in smokers compared with nonsmokers ,and no significant changes was found in mean activity of serum AST , ALT and ALP between male and female smokers.

التدخين يسبب العديد من الآثار في الجسم البشري. ويمكن دراسة هذه الآثار عن طريق قياس مختلف القياسات البيوكيميائية في الدم. في هذه الدراسة (3) وقد تم قياس القياسات البيوكيميائية (AST الألانين اسبارتاتي، ALT الألانين ألانين، والقلوي ALP الفوسفاتيز) في الدم من المتطوعين 139 اصحاء، من بينهم 88 من المدخنين (55 من الذكور والإناث 33) وغير المدخنين 51 كعنصر تحكم مجموعة، من أجل دراسة تأثير التدخين على هذه انزيمات الكبد، والمقارنة يعني الانزيمات الأنشطة بين المدخنين من الذكور والإناث. انها وجدت زيادة كبيرة من المصل AST، ALT، ونشاط حزب العمال الاسترالى لاحظت لدى المدخنين بالمقارنة مع غير المدخنين، و ولم يتم العثور على تغييرات كبيرة في نشاط متوسط ​​AST في مصل الدم، ALT و ALP بين المدخنين من الذكور والإناث.


Article
Estimation of Serum Uric Acid, Urea and Creatinine in Essential 152 Hypertensive Patients
تقدير حمض اليوريك المصل، واليوريا والكرياتينين في 152 الأساسية ارتفاع ضغط الدم المرضى

Author: Isra’a H. AL – Hamdani اسراء الحمداني
Journal: The Medical Journal of Tikrit مجلة تكريت الطبية ISSN: 16831813 Year: 2010 Volume: 1 Issue: 161 Pages: 152-159
Publisher: Tikrit University جامعة تكريت

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Abstract

Hypertension is one of the most common world disease, which caused many effects on human body. Renal dysfunction is one of the most important adverse effects of the hypertension, which can be studied by measurement of clinical biochemical parameters in blood. In the current study serum uric acid, urea and creatinine had been measured in blood of 82 hypertensive patients including ( 45 males & 37 females ), and 43 apparently healthy volunteers as control group, in order to identify the effect of hypertension on some renal function test such as serum uric acid, urea and creatinine in comparison with control group and compared these parameters between male and female hypertensive patients. From the data collected it found there are a significant increase in the mean values of serum urea and creatinine in hypertensive patients compared with control , while no significant difference in serum uric acid between hypertensive patients and control group. The results of comparison between male and female hypertensive patients for serum uric acid , urea and creatinine showed that there was a significant increase in mean value of serum uric acid in male than that in female hypertensive patients and no significant change was found in the mean values of serum urea and creatinine between male and female hypertensive patients.

ارتفاع ضغط الدم هو واحد من مرض العالم الأكثر شيوعا، والتي تسبب العديد من الآثار على الجسم البشري. اختلال وظيفي كلوي هي واحدة من الآثار الضارة الأكثر أهمية في ارتفاع ضغط الدم، والتي يمكن دراستها عن طريق قياس البارامترات الحيوية السريرية في الدم. في الدراسة الحالية حامض اليوريك في الدم، وكان قد تم قياس اليوريا والكرياتينين في الدم من 82 مريضا بارتفاع ضغط الدم بما في ذلك (45 ذكور وإناث 37)، و 43 متطوعا من الأصحاء على ما يبدو السيطرة على المجموعة، من أجل تحديد تأثير ارتفاع ضغط الدم في بعض وظائف الكلى اختبار مثل حمض اليوريك في الدم واليوريا والكرياتينين في مقارنة مع مجموعة مراقبة ومقارنة هذه المعايير بين مرضى ارتفاع ضغط الدم من الذكور والإناث. من البيانات التي تم جمعها وجدت أن هناك زيادة كبيرة في متوسط ​​القيم من اليوريا والكرياتينين في مصل الدم لدى المرضى المصابين بارتفاع ضغط الدم بالمقارنة مع الرقابة، في حين لا يوجد فرق كبير في حمض اليوريك في الدم بين المرضى الذين يعانون ارتفاع ضغط الدم والسيطرة على المجموعة. نتائج المقارنة بين مرضى ارتفاع ضغط الدم من الذكور والإناث لحمض اليوريك في الدم، وأظهرت اليوريا والكرياتينين أن هناك زيادة كبيرة في قيمة وسطى من حمض اليوريك في الدم في الذكور منه في الإناث، ومرضى ارتفاع ضغط الدم ولم يتم العثور على تغير كبير في القيم المتوسطة من اليوريا والكرياتينين في مصل الدم بين مرضى ارتفاع ضغط الدم من الذكور والإناث.


Article
Measurement of Serum Uric Acid, Urea and Creatinine in PregnantWomen
قياس حمض اليوريك المصل، واليوريا والكرياتينين في PregnantWomen

Author: Isra’a H .AL-Hamdani اسراء هاشم الحمداني
Journal: The Medical Journal of Tikrit مجلة تكريت الطبية ISSN: 16831813 Year: 2006 Volume: 2 Issue: 122 Pages: 31-35
Publisher: Tikrit University جامعة تكريت

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Abstract

Serum uric acid ,urea and creatinine were assessed in normal pregnant women in
order to identify the association between these biochemical parameters and gestational
periods (first and third trimester) compared to those of normal non- pregnant women as a
control group. The study has been done on (53) normal pregnant women, but only (38)
continued the follow up through out to third trimester, and a comparison was done with (37)
normal non-pregnant women as a control group. The mean of serum uric acid, urea and
creatinine showed a significant lower values in pregnant group during the 1st trimester of
pregnancy than the control group. While the mean values of serum uric acid, urea and
creatinine show a non significant decrease through out the 3rd trimester compared to the
control group. There was a significant difference in serum uric acid and creatinine between
the 1st and 3rd trimester which were higher in the 3rd trimester than the 1st trimester of
pregnancy, but no significant difference in serum urea between the 1st and 3rd trimester.

وجرى تقييم حمض اليوريك في الدم واليوريا والكرياتينين في النساء الحوامل طبيعي في النظام />
نقاط (الربع الأول والثالث) مقارنة من النساء غير الحوامل بشكل طبيعي تحكم />
واصلت متابعة من خلال الخروج إلى المرحلة الثالثة من الحمل، وتم إجراء مقارنة مع (37) />
قيم أدنى كبيرة في مجموعة حامل خلال الأشهر الثلاثة 1 من الحمل />
تظهر انخفاضا غير هام من خلال الخروج من الفصل 3 مقارنة مع مجموعة مراقبة
. كان هناك اختلاف كبير في حمض اليوريك في الدم والكرياتينين بين
و1 و 3 في الفصل التي كانت أعلى في الفصل 3 من الفصل 1 من الحمل />


Article
Alterations of Serum Calcium, Phosphorus and AlkalinePhosphatase in Postmenopausal Women
تغيرات الكالسيوم , الفسفور وانزيم الفوسفاتيز القاعدي في مصل دم النساء بعد سن اليأس

Author: Isra'a H. Al- Hamdani أسراء حكمت الحمداني
Journal: Tikret Journal of Pharmaceutical Sciences مجلة تكريت للعلوم الصيدلانية ISSN: 18172716 Year: 2010 Volume: 6 Issue: 1 Pages: 37-43
Publisher: Tikrit University جامعة تكريت

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Abstract

ln the present study 3 biochemical parameters ( Calcium, Phosphorus and Alkaline
phosphatase) has been measured in blood of 1 1 1 apparently healthy volunteers
women, including 41 apparently healthy premenopausal women aged between ( 21-
42 ) years as a control group and 70 apparently healthy postmenopausal women ( the
menopause occur normally ) aged between ( 50- 69 ) years which divided into two
ug. gioupr. From the results it is found that there were a significant difference of
r.ru* .ul.ir-, phosphorus and alkaline phosphatase between postmenopausal
women groltp and control group also the current study showed that the serllm calcium
and phosphorus declines with age within postmenopausal women grollp, while the
mean value of alkaline phosphatase activity showed a significant increase with
increasing age in postmenopausal women group.

Keywords


Article
Evaluation of Serum Alanine aminotransferase, Aspartateaminotransferase and Alkaline phosphatase in Adult ObeseNinava People.
تقدير انزيمات ناقل الامين الالنين, ناقل الامين الاسبارتيت وانزيم الفوسفاتيز القاعدي في مصل دم الاشخاص البالغين المصابين بالسمنة في نينوى

Author: Isra'a H. Al-Hamdani اسراء حكمت الحمداني
Journal: Tikret Journal of Pharmaceutical Sciences مجلة تكريت للعلوم الصيدلانية ISSN: 18172716 Year: 2010 Volume: 6 Issue: 1 Pages: 63-69
Publisher: Tikrit University جامعة تكريت

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Abstract

Obesity is a well known cause of a lot of health problems, these problems can be
further evaiuated by biochernical studies. In the present study 3 biochemical
parameters represented as: Alanine aminotransferase (ALT), Aspaftate
aminotransfetur. leSf; and Alkaline phosphatase (ALP) has been measured in blood
of 69 apparentiy healthy obese subjects (30 males& 39 females) which divided into
two subgroups according to body mass index (BMI) (30- 34.9) & (35- 39.9). The
control groui in"tuded 32 apparently healthy with normal weight subjects. The aim
of this research is to study the effect of obesity on the activity of aminotransferase
enzymes (ALT& AST), and alkaline phosphatase (ALP) in Ninava compared to
.o,1irol group (sr-rbjects with normal weight), in addition, to study the biochemical
changes of these enzymes within obese group which classified according to the BMI
and sex. According to the results which recorded in this study, there was a significant
increase in the activity of ALT, AST, and ALP in obese subjects when compared to
controls, also there is no significant effect of BMI on these enzymes in obese group
rvith a higher mean activities of three enzymes in class II obese group (BMI 35- 39 '9).
The results also showed no significant difference between male and female in obese
subjects for the mean activities of these enzymes.

Keywords


Article
The Effect of Xylitol Preparations on Sa-livary Gland Function and Oral Health

Authors: Isra'a H Al–Hamdani --- Jawnaa K Mammdoh --- Nahla O M Tawfik
Journal: Al-Rafidain Dental Journal مجلة الرافدين لطب الأسنان ISSN: 18121217 Year: 2010 Volume: 10 Issue: 1 Pages: 38-48
Publisher: Mosul University جامعة الموصل

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Abstract

Aims: To evaluate the effect of different xylitol preparations (chewing gum and strips ) on gingival, plaque indices and salivary fluid composition (calcium, total protein and uric acid ). Materials and Methods: Twenty nine healthy dental students aged 20-24 years, were divided randomly into two groups, the first group used chewing gum sweetened with xylitol and the second took xylitol strips for 21 days. The plaque and gingival indices were examined at the baseline and at the end of treatment, together saliva samples were collected in the same periods for the measurement of salivary flow and salivary concentration of calcium, total protein and uric acid. Results: The results confirmed on going changeability of the oral cavity environment after treatment with xylitol preparations in both groups. There were reduction in plaque and gingival indices in both groups, but it was significantly reduced in strip treated group (P< 0.0001 and P<0.01 respectively). Salivary concentration of total protein was significantly decreased in strip group ( P <0.05 ) and in gum group ( P<0.0001 ) against baseline Val-ues. Xylitol strips have pronounced effect on the gingival index (P<0.0001) when compared with xyli-tol gum . Conclusions: The regular use of different xylitol preparations has its protective effects on the oral health hygiene. Key Words: xylitol, Salivary flow, Gingival index, Plaque index, Oral health .

Keywords


Article
Effect of Stress on the Composition and Flow Rate of Saliva

Authors: Nahla OM Tawfik --- Isra'a H Al-Hamdani --- Karama M T Al-Nuaimy
Journal: Al-Rafidain Dental Journal مجلة الرافدين لطب الأسنان ISSN: 18121217 Year: 2012 Volume: 12 Issue: 1 Pages: 66-70
Publisher: Mosul University جامعة الموصل

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Abstract

Aims: To assess the effect of acute psychological stress on some salivary glands functions. Materials and Methods: Twenty-three undergraduate dental students participated in this study. They were asked to provide two samples of unstimulated whole saliva for 5 minutes, the first sample before amid- year oral academic examination and subsequently the second, one month later in a non stressful situation (after holiday break) as control group. Salivary flow in one minute was determined, in addition, total protein, albumin, uric acid and calcium levels in saliva were assessed using determination kits method from Biolabo (France). Results: The results showed a significant stress mediated decrease in the sali-vary calcium concentration (0.230.21 mmol/L) by -78.50% in comparison with non stressful condi-tion. Salivary flow level (0.62  0.28 ml /min) and albumin concentration (16.3913.69 mg/100ml) were decreased by (- 4.62% and -37.30% respectively), while uric acid (1.671.13 mmol/L) and total protein concentrations (1.030.69 g/100ml) were elevated by 9.56% and 10.60% respectively. Not all these changes were statically significant. Conclusions: These results suggest that the acute psychologi-cal stress exerts its influence on salivary composition and this will increase the value of saliva as dy-namic biological fluid in controlling the oral health.

Keywords

Saliva --- stress --- total protein --- albumin --- uric acid --- calcium

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