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Article
The efficacy of a combined corticosteroid and anti fungal therapeutics in the management of oral lesions

Author: Jamal N. Ahmed
Journal: Journal of baghdad college of dentistry مجلة كلية طب الاسنان بغداد ISSN: 16800087 Year: 2006 Volume: 18 Issue: 1 Pages: 46-48
Publisher: Baghdad University جامعة بغداد

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Abstract

ABSTRACT
Background: Corticosteroid is a medication widely used in the treatment of the chronic inflammatory diseases of the oral mucosa. Treatment with cortisone is complicated with the secondary oral candidiasis. The purpose of this study was to find the efficacy of a combined therapeutics (cortisone and antifungal) in the treatment of chronic oral lesions.
Materials and methods: Eighteen patients were selected for this study, and they were divided into three groups. The Pl group received combined therapeutics (cortisone and antifungal), the 2nd group received cortisone only and the 3rd group received placebo.
Results: The results showed that fungal infection in 42% of the 2nd group and there was no evidence of infection in group which received combined therapy. In addition, the clinical signs and symptoms were improved.
Conclusions: These findings suggest the use of an anti fungal in the management of chronic oral lesion that requires prolong administration of cortisone.
Key words: Antifungal, oral lesions. (J Bagh Coll Dentistry 2006; 18(1) 46-48)

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Article
Diagnosis of the angular hyperkeratotic lesions and the incidence of the etiologic factors

Author: Jamal N. Ahmed جمال احمد
Journal: Journal of baghdad college of dentistry مجلة كلية طب الاسنان بغداد ISSN: 16800087 Year: 2012 Volume: 24 Issue: 2 Pages: 51-55
Publisher: Baghdad University جامعة بغداد

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Abstract

Background: Hyperkeratotic lesions located at the angle of the mouth are common among patients attendingdental clinics. Most dentists are unaware of it since the patients are not seeking care. The purpose of the presentstudy was to find out the incidence of the diagnosed lesions and their relation with the etiologic or initiating factors.Materials and methods: A total of (112) patient’s (62) males and (50) females having angular hyperkeratotic lesionswere selected from patients attending the dental clinic in Baghdad dental school. The clinical diagnosis and theprogression of the lesions were conducted by using 1% toluidine blue stain to confirm the premalignant potentialsand to delineate the margins of the lesion for the biopsy. Microscopic examinations were done for the confirmationof the final diagnosis. The associating factors like smoking, alcohol, dental irritation, prosthesis, systemic diseases, andangular chelitis were recorded in the patient information sheet for the result analysis.Results: The results showed that the benign hyperkeratotic lesions were the higher (36.6%) in distribution, while themalignant neoplasms were the 2nd (25.89%) in frequency, followed by premalignant lesions (21.42%), lichen planus(12.5%), and benign growth (3.57%). Smoking habit was the most common associating factor (54.6%), followed byangular chelitis (48.2%), dental irritation (43.7%), systemic diseases (35.7%), dental prosthesis (28.5%) and alcoholconsumption 0.05%.Conclusion: The hyperkeratotic lesions occurred in a wide range of ages. The benign lesions were the most commontypes. However a significant number of cases had premalignant and malignant changes. The presence of theassociating factors acting alone or in combination were having a role in the existence of the lesions. Thepremalignant potentials increase with age and the chronicity of the associating factors such as smoking and angularchelitis were having a significant role in existence of the lesions. In addition, the results showed that the angularhyperkeratotic lesions existed in the majority of the patients were bilateral in behavior.


Article
The incidence of oral lesions induced by chronic irritations among patients attending Oral Diagnosis Clinic

Authors: Riyadh O. Alkaisi --- Jamal N. Ahmed
Journal: Journal of baghdad college of dentistry مجلة كلية طب الاسنان بغداد ISSN: 16800087 Year: 2006 Volume: 18 Issue: 3 Pages: 39-42
Publisher: Baghdad University جامعة بغداد

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Abstract

ABSTRACT
Background: Chronic irritations can produce a variety of clinical lesions in the oral cavity, such as; reactive hyperplasia, red and white lesions, traumatic ulcers and swellings The purpose of this study was to find out the incidence and the main causes of these lesions in Iraqi patients during the last two years.
Materials and methods: A total of 340 patients attending the diagnosis clinic within 2 years (2003 and 2004) were examined clinically and diagnosed thorough a search for the etiological factors of the lesions mentioned in this study.
Results: Out of 340 patients complaining of various oral lesions, only 146 patients were diagnosed as having oral lesions due to chronic irritation. Highest frequency was reactive hyperplasia (35.6%), followed by traumatic ulcers (24.7%). red lesions (19.9 %), white lesions (15 %) and swellings (4.8 %) respectively. Mechanical irritation represents the major causative factor in creating the traumatic lesions.
Conclusions: The incidence of oral lesions due to chronic irritation was increased (mainly traumatic ulcers) due to health negligence of mouth hygiene, besides the increasing incidence of smoking and other bad habits.
Key words: Oral lesions, chronic irritations. (J Bagh Coll Dentistry 2006; 18(3)39-42)

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Article
Determination of the effect of stress on the salivary cortisol level among sample of university students having myofacial pain

Authors: Rana M. Hasan --- Jamal N. Ahmed
Journal: Journal of baghdad college of dentistry مجلة كلية طب الاسنان بغداد ISSN: 16800087 Year: 2013 Volume: 25 Issue: 3 Pages: 87-90
Publisher: Baghdad University جامعة بغداد

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Abstract

Background: Psychological stress is considered the major etiological factor precipitating myofacial pain andtemporomandibular disorders.It is known that stress induce various adaptational responses of physiologic systems. Theprocess includes increase in the activity of the hypothalamic -pituitary-adrenal axis which promotes cortisol secretion.Salivary cortisol has been used as a measure of free circulating cortisol levels.The use of salivary biomarkers hasgained increased popularity since collecting samples is non-invasive and painless. The aim of thisstudy was toevaluate the level of cortisol in saliva among sample of university students having myofacial pain, during the finalexam period and whether this finding could have a significant value as a symptomatic psychobiological marker.Materials and Methods: Ninety eight (98) university students were enrolled in this study. Fifty(50) were with myofacialpain (symptomatic) and forty eight (48) were without myofacial pain (asymptomatic) as a control group.Eachstudent with myofacial pain was examined according to Research Diagnostic Criteria for TemporomandibularDisorders. Saliva sample were collected from each subject before final examination and three months later forbiochemical analysis of cortisolusing ELISA test.Results: A highly significant difference in salivary cortisol level between the two periods for both the study and controlgroups, and a non-significant difference between the two groups in before examination period. A negativeassociation has been observed between the level of salivary cortisol and severity of pain and a highly significantimprovement of pain between the final examination periods and three months later.Conclusions: Dental students perceived a higher level of stress prior to the final exam was associated with raisedsalivary cortisol levels which could be considered as a useful non-invasive biomarker for measuring acute stress

Keywords

Stress --- Cortisol --- Myofacial pain


Article
The use of anterior mid stop point splint in comparison with full coverage splint therapy in the management of temporomandibular joint dysfunctions

Authors: Kadhum Al Sudani --- Jamal N. Ahmed --- Ihsan A. Kamel
Journal: Journal of baghdad college of dentistry مجلة كلية طب الاسنان بغداد ISSN: 16800087 Year: 2006 Volume: 18 Issue: 3 Pages: 34-38
Publisher: Baghdad University جامعة بغداد

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Abstract

ABSTRACT
Background: The effectiveness of occlusal splint in decreasing the symptoms of temporomandibular joint dysfunctions has been demonstrated in many studies. There are many designs of acrylic splint fabricated as a therapeutic device in the management of various TMJ problems. The purpose of this study was to evaluate the use of anterior mid stop point splint (AMSP) in comparison with the full coverage (conventional flat splint) in the management of temporomandibular joint dysfunctions.
Subject and methods: Thirty patients were chosen for this study. They were of both genders with age ranged between (21-60) years. They were divided into two groups. The first group (15 patients) was treated with anterior mid stop point splint, while the second group (15 patients) was treated with full coverage flat surface splint. Clinical and electromoygraphic evaluation were performed for each patient before and after treatment.
Results: It has shown that 93.3% improvement of the symptoms of pain in the first treatment group (AMSP splint), and 53.3% improvement in the second treatment group (full coverage splint) during the course of treatment (45 days).
The opening capacity was increased in an average of 9.9mm and 7.3mm for the same groups respectively in the same period. Electromyographic investigation showed 40.54% resting potential of temporalis in patients treated with anterior mid stop point, While 18.21% resting potential of temporalis muscle in patient treated with full coverage splint in 45 days of therapy. In other word, the ability to re-establish a smooth coordinated musculo-skeletal relation, balanced occlusion, and effective function through treatment was evaluated in this project.
Conclusion: The findings demonstrated that anterior mid stop point splint is more useful in comparison with smooth surface full coverage splint in the management of temporomandibular dysfunctions.
Keywords: Anterior mid stop point splint, full coverage splint, TMJ dysfunctions. (J Bagh Coll Dentistry 2006; 18(3)34-38)

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Article
Assessment of the oral findings, salivary oxidative status and IgA level among group of workers exposed to petroleum pollutants in Al-Daura oil refinery

Authors: Ameer S. Hamza --- Jamal N. Ahmed جمال نوري احمد
Journal: Journal of baghdad college of dentistry مجلة كلية طب الاسنان بغداد ISSN: 16800087 Year: 2015 Volume: 27 Issue: 2 Pages: 48-53
Publisher: Baghdad University جامعة بغداد

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Abstract

Background: Oil refinery workers are continuously exposed to numerous hazardous materials. Petroleum contains theheavy metals as a natural constituent or as additives. These metals induce the production of ROS which associatedwith an oxidative damage to DNA, proteins, and lipids. This study was conducted to assess the salivary levels ofheavy metals, salivary oxidative status, oral immunological activity (salivary sIgA) and assessment of the oral findingsamong the workers of Al-Daura oil refinery in Baghdad city.Subjects, Materials and Methods: This study was done in Al-Daura oil refinery; samples consist of 60 workers involved inrefinery processes (study group) and 20 non-workers (control group). Oral examination and saliva collection wasdone to assess the oral findings and measurement the level of heavy metals (lead and cadmium), oxidative status(MDA and SOD) and secretary IgA.Results: salivary lead and cadmium was higher in study group (6.34 μg/dl and 0.56 μg/l) than that of control group(3.3 μg/dl and 0.34 μg/l) with highly significant difference (p<0.001). A significant increase (p<0.05) was found insalivary MDA (15.3 ng/ml) and salivary sIgA (464.36 μg/ml) and significant decrease in salivary SOD (1895.1 pg/ml)among the study group. Lead has shown significant linear correlation with MDA and IgA. A significant reversecorrelation was found between heavy metals (lead and cadmium) and SOD. The oral examination revealed no orallesions of interest.Conclusion: Workers in Al- Daura oil refinery exposed to pollution with heavy metals (Pb and Cd) which wasassociated with changes in the biochemical and immunological findings among the oral cavity

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Article
Orofacial, radiographic and salivary changes in thalassemia a major patients in Mosul

Authors: Jamal N. Ahmed B.D.S., M.Sc د. جمال احمد --- Mohammed I. M. Norri B.D.S., M.Sc د. محمد نوري
Journal: MUSTANSIRIA DENTAL JOURNAL مجلة المستنصرية لطب الاسنان ISSN: 18138500 Year: 2005 Volume: 2 Issue: 2 Pages: 306-323
Publisher: Al-Mustansyriah University الجامعة المستنصرية

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Abstract

Thalassaemia is considered one of the major health problem, which is widely,distributed throughout the worldClinical orofacial, and radiographical examinations, in addition to the physicaland biochemical analysis of the whole unstimulated saliva had been studied in Majorthalassaemia patients (MTP) and the results compared with that of the normal.subjects)The study included (254) subjects. Thalassaemia patients (study groupcomposed of (201) patients and non-thalassaermic. patients (control group) composedof (53) subjects. Each group was divided into three subgroups according to their ages.and sex distribution to study the chronological changes ofthe diseaseThe first,second, and third groups were (6-11, 12-17,2 18) years old.respectivelyThe results of the study showed that, there was a significant difference in,occlusal relation between thalassaemie and non·thalassaemic groupsThalassaemic patients had a significant degree of malocclusion and high.significant degree of teeth discoloration than non-thalassaemie patientsThere were significant difference in oral hygein indices between thalassaemieand non-thalassaemie patients and even between male and female thalassaemie.patientsThe intraoral radiographical assessment of the major thalassaemie patientsshowed that, there was thinning of the lamina dura and bone marrow hyperplasia.which were significant when compaired with the non-thalassaemie patientsFacial pigmentation and saddle no se were highly significant in major.thalassaemie than non-thalassaemie patients


Article
Immunohistochemical Expression of P53 and bcl-2 in benign and malignant salivary glands tumors

Authors: Dr. Husam Omer Mohammed M.Sc ** د. حسام عمر --- Dr. Jamal N. Ahmed M.Sc* د. جمال احمد --- Dr. Natheer H. AL-Rawi M.Sc, Ph.D * د.نذير الراوي
Journal: MUSTANSIRIA DENTAL JOURNAL مجلة المستنصرية لطب الاسنان ISSN: 18138500 Year: 2007 Volume: 4 Issue: 1 Pages: 13-21
Publisher: Al-Mustansyriah University الجامعة المستنصرية

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Abstract

Objectives: Salivary glands tumors are relatively uncommon neoplasm with widely variable histopathologic and biologic characteristics. Alteration in some proto-oncogenes and tumor suppressor genes may lead to the development and progression of these tumors. The purpose of the present study was to analyze the immunohistochemical expression of P53 and bcl-2 in some salivary gland tumors in relation to tumor size, histological grade and extent of invasion.Study Design: The series consisted of 22 formalin-fixed paraffin embedded blocks of salivary glands tumors collected from the files of Oral pathology Department./College of Dentistry/ Baghdad University. The specimens consisted of (10) benign salivary gland tumors ( Pleomorphic Adenomas) and (12) malignant salivary gland tumors [ (2) Carcinoma ex Pleomorphic Adenoma, (3) Muco-Epidermoid Carcinoma, (2) Adenocarcinoma (5) Adenoid cystic carcinoma]. These were analyzed for immunohistochemical detection of P53 and bcl-2 in their cell types.Results: Pleomorphic Adenoma showed negative expression of P53 and bcl-2 in 70% of cases, whereas all malignant salivary glands tumors were positive for P53 and bcl-2. P53 and bcl-2 immune-reactivity were associated with larger tumor size, higher tumor grade and greater extent of invasion without reaching statistical significance level.Conclusion: P53 expression could be used as a useful tumor marker for malignant transformation of Pleomorphic adenoma and bcl-2 expression could be used as a useful monitor for measuring the aggressiveness of these neoplasms.


Article
Salivary analysis and oral symptoms in controlled asthmatic patients

Authors: Widad F. Jaber B.D.S., M.Sc *. د. وداد جابر --- Jamal N. Ahmed B.D.S., M.Sc ** د. جمال احمد --- Ahlam Hammed B.D.S., M.Sc ** د.احلام احمد
Journal: MUSTANSIRIA DENTAL JOURNAL مجلة المستنصرية لطب الاسنان ISSN: 18138500 Year: 2005 Volume: 2 Issue: 1 Pages: 52-68
Publisher: Al-Mustansyriah University الجامعة المستنصرية

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Abstract

Asthma is a common inflammatory condition of lung airways. Its cause isincompletely understood .Patients with bronchial asthma are affected both by the disease and its treatment .The purpose of our study was to examine the salivary composition in asthmatic patients ,and study the association between asthma and occurrence of selected oral symptoms .The study was divided into two phases. In the first phase (salivary analysis) thesalivary composition and unstimulated salivary flow rates of 50 asthmatic patients werecompared with that of 25 non -asthmatic subjects. In the second phase (questionnairsurvey) the occurrence of symptoms of oral diseases in asthmatics (n=I I3) was comparedwith that of non—asthmatic subjects (n=ll I .)In addition to the symptoms of oral diseases, data on background informationwere taken. The results of salivary analysis showed no statistically significant differencesbetween the asthmatic and non- asthmatics concerning the salivary flow rate andcomposition, However, the asthmatic saliva samples showed lower potassium and higherinorganic phosphorus levels .In the questionnair survey , the subjects reported more symptoms (dry mouth ,soremouth , halitosis , pain in Temporomandibular jiont (TMI) , stuffiness in (TMI) andclicking in (TMI) compaired to the controlled group. The presence of asthmaprecipitating factors and medication used had a considerable effect on the probability ofhaving symptoms of oral diseases when compaired to non- users

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