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تقييم مستوى مكوني المتمم C3 و C4 في مصول المرضى المصابين بالسرطان
Evaluation of complement components C3 and C4 in serum of patient with neoplastic diseases

Authors: Mohamed Abbas Mehdy --- Shereen Jawad Al-Ali --- Zeenah weheed Atwan
Journal: JOURNAL OF THI-QAR SCIENCE مجلة علوم ذي قار ISSN: 19918690 Year: 2010 Volume: 2 Issue: 3 Pages: 3-7
Publisher: Thi-Qar University جامعة ذي قار

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Abstract

The aim of this study is to evaluate the level of complement components C3 and C4 in serum of cancer patients to find which activation pathway of the complment system has the more effect in these cases . A total of 20 blood samples were collected from cancer patients , C3 and C4 complement components were measured by SRID plates . The results showed a significant elevation in C3 and C4 level in compartion with control group. C3 level was higher than C4 level which suggest that the activation of classical pathway in cancer patients .

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BETA-2 MICROGLOBULIN: A NOVEL BIO-MARKER ASSISTING IN THE DIAGNOSIS OF LYMPHOMA: A STUDY OF 669 NEWLY DIAGNOSED LYMPHOMA CASES IN THE SOUTH OF IRAQ

Authors: Abdalla Al-Abbadi --- Jawad Al-Ali --- Zuhair Al-Barazanchi
Journal: Basrah Journal of Surgery مجلة البصرة الجراحية ISSN: 16833589 / ONLINE 2409501X Year: 2014 Volume: 20 Issue: 2 Pages: 89-94
Publisher: Basrah University جامعة البصرة

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Abstract

Beta 2 microglobulin is a known marker used in the follow up and monitoring therapy of patients with hematological malignancies. However, its assistant role in the diagnosis of some of them, like lymphomas is less highlighted. Thus, this study was designed as a part of a larger, wide scale study, to clarify the help of B2MG in the support of the diagnosis of different types of lymphoma. A total of 669 newly diagnosed, pre-treated lymphoma cases were investigated for B2MG using the ELFA/mini VIDAS system and the results showed an elevated level of B2MG among both Hodgkin & non-Hodgkin, adults and childhood and nodal and extranodal lymphomas, with a significant increase among non-Hodgkin and extranodal type of lymphomas, a finding that may make its use as a diagnostic marker is helpful. Those results were comparable to some and contradicting to other studies. Further future studies are in need to consolidate this.

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