research centers


Search results: Found 1

Listing 1 - 1 of 1
Sort by

Article
Clinicopathological, immunohistochemical charachtaristic and the outcome of Hodghkin lymphoma patients in Erbil city, Iraq

Authors: Lilan Bahzad Mohammedzaki --- Kawa Muhammedamin Hasan --- Ranan Kardagh Polus --- Ahmed Khudair Yassin
Journal: Iraq Joural of Hematology المجلة العراقية لامراض الدم ISSN: 20728069/25432702 Year: 2019 Volume: 8 Issue: 1 Pages: 14-20
Publisher: Al-Mustansyriah University الجامعة المستنصرية

Loading...
Loading...
Abstract

BACKGROUND: Hodgkin lymphoma (HL) has unique epidemiological features with diversifiedpathologies and exhibits considerable clinicopathological variations in different parts of the world.OBJECTIVES: We aimed in this study to assess clinic-pathological features, immunohistochemistryand outcome of HL patients treated in Erbil, northren Iraq.PATIENTS AND METHODS: This was a retrospective study conducted in Nanakaly Hospital forblood diseases and oncology in Erbil, North Iraq; a total of 125 patients diagnosed between January2012 and December 2016 were involved; they were assessed for their clinical characteristics andhistopathology and immunophenotyping findings and their outcome was evaluated as well.RESULTS: The median age was 28 years (range: 18–71 years); 55% were male and 41% had StageII disease; common histological type is nodular sclerosis (51.2%) followed by mixed cellularity (43.2%);CD30 was positive in nearly all cases of classical HL, and CD15 was positive in 98.7% and CD20was positive in 75% in nodular lymphocyte predominant subtype. Most of the patients receivedadriamycin, bleomycin, vinblastine, and dacarbazine chemotherapy, and the 5‑year overall survivalin our study is 70%. Advanced stage (IV), high lactate dehydrogenase level, low hemoglobin, andsplenomegaly are significant predictors for poor survival.CONCLUSION: Our patient exhibited outcomes that were lower to those reported in developedcountries.

Listing 1 - 1 of 1
Sort by
Narrow your search

Resource type

article (1)


Language

English (1)


Year
From To Submit

2019 (1)