research centers


Search results: Found 2

Listing 1 - 2 of 2
Sort by

Article
Inhibitory Effect of Parsley (Petroselinum Crispum) Juice Against Some Urinary Pathogens in Vitro

Author: Khalida Kareem Al-Kareemi
Journal: Iraqi Academic Scientific Journal المجلة العراقية للاختصاصات الطبية ISSN: 16088360 Year: 2012 Volume: 11 Issue: 3 Pages: 336-342
Publisher: The Iraqi Borad for Medical Specialization المجلس العراقي للاختصاصات الطبية

Loading...
Loading...
Abstract

ABSTRACT:BACKGROUND:Information's on the potency of many medical plants against microorganisms are scanty, and in the current wave of antimicrobial resistance against chemotherapeutic drugs, there is a need to search for plants that could be resistance-free and affordable.OBJECTIVE:The objective of this study was to investigate the antibacterial effects of Parsley (Petroselinum crispum) against uro-pathogens and to compare with the effect of some drugs used for the treatment of urinary tract infection caused by different Gram positive and Gram negative bacteria.MATERIALS & METHODS:A total of thirty eight Gram positive and Gram negative bacteria(Escherichia coli ,Proteus sp.,Enterobacter spp.,Pseudomonas aeruginosa, Klebsiella sp. , Staphylococcus aureus) isolated from urine samples of different child patients between first of June 2011 to first of July 2011 admitted to Children Mel fare Teaching Hospital in Baghdad were tested against different dilutions of Parsley (100%,1:1,1:5,1:10:1:15,1:20) to examine the inhibitory activity in vitro ,in addition antibiotic susceptibility test was done.RESULTS:All isolates showed sensitivity to concentrated parsley 100% concentration except Pseudomonas aeruginosa isolates, the highest effect observed on Proteus sp. and Staphylococcus aureus isolates, while inhibitory effect stopped after 1:1 dilution against all isolates, while in antibiotics therapy (29) isolates were resistant to Co-Trimoxazole and Cefotaxime and (30)isolates showed resistance to Tri-imetheprim+clavulanic acid.CONCLUSION:It seems that Parsley has potent antibacterial activity against some uropathogens in vitro.


Article
Antifungal Activity of Diacetyl Compound against Candida Isolates in Vitro
دراسة الفعالية ضد ميكروبية لمركب Diacetyl ضد albicans Candida

Authors: Sinan Ezzat Saeed --- Ban Auday Abdul Sattar --- Khalida Kareem Al-Kareemi
Journal: journal of the college of basic education مجلة كلية التربية الاساسية ISSN: 18157467(print) 27068536(online) Year: 2012 Volume: 18 Issue: 75 Pages: 67-74
Publisher: Al-Mustansyriah University الجامعة المستنصرية

Loading...
Loading...
Abstract

To overcome the development of drug resistance, it is necessary to find a new class of antimicrobial compounds possessing different mechanism or chemical properties from those that are used commonly for the treatment of the diseases which are caused by Candida albicans. This study was designed to investigate the antifungal activity of Diacetyl against Candida albicans isolates with a total of forty eight Candida albicans isolates which was isolated from sputum, vagina and urine sample of different patients were tested against several concentrations of Diacetyl compound (30,60,120,180)µg/ml and for different incubation time to examine the inhibitory activity of the compound in vitro. All urine isolates showed 100% complete inhibition to(30,60,120,180) µg/ml concentrations after 24,48,72 hrs incubation at 37C°,while only three vaginal isolates 30% and eleven sputum isolates 42.3% showed resistance after 48 hrs incubation to 30 and 60 µg/ml concentrations. It seems that Diacetyl compound has a potent antifungal activity against Candida albicans in vitro.

للتغلب على مقاومة المضادات من الضروري ايجاد اصناف جديدة من المركبات الضد ميكروبية ذات ميكانيكية وتركيب كيميائي مختلف عن المواد الضد ميكروبية المستخدمة حاليا لعلاج الاصابات الناتجة عن الاصابة ب Candida albicans .اجريت التجربة على ثمان واربعون عزلة من Candida albicans المعزولة من القشع,المسحات المهبلية و الادرار من مختلف المرضى وتم استخدام تراكيز مختلفة من Diacetyl 30,60,120,180 مايكروغرام/مل وباوقات حضن زمنية مختلفة 24,48,72 ساعة في درجة حرارة 37° مئوية.كل عينات الادرار لم تظهر اي نمو في كل التراكيز المستخدمة بعد 24,48,72 ساعة بينما اظهرت ثلاث عزلات فقط من Candida albicans المعزولة من المهبل 30% واحدى عشر عزلة من العزلات المعزولة من القشع 42.3% مقاومة بعد 48 ساعة من الحضن لتركيز 30 و 60 مايكروغرام/مل من Candida albicans.التجربة تشير الى ان مركب Diacetyl له فعالية ضد ميكروبية ضد بعض عزلات Candida albicans.

Keywords

Listing 1 - 2 of 2
Sort by
Narrow your search

Resource type

article (2)


Language

Arabic (1)

English (1)


Year
From To Submit

2012 (2)