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Molluscum Contagiosum in Baquba City Epidimiological Study with Identification of Mc Viruses by Polymeras Chain Reaction

Authors: Khudhair Khalf Al-Kayalli --- Raghad Ibrahim Ahmed --- Brooj Mohammad Irzuqy --- Wathek Mohammed Husain
Journal: Diyala Journal of Medicine مجلة ديالى الطبية ISSN: 97642219 Year: 2015 Volume: 8 Issue: 1 Pages: 8-13
Publisher: Diyala University جامعة ديالى

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Abstract

Background: Molluscum contagiosum is a DNA virus, which may infect the mucous membrane, it is caused by Molluscipox virus and there are four types (MCV1-4). The sites of predilection of lesions are the face and neck, both genders equally affected and most commonly seen in childhood age group. Objectives: To study the epidemiological variables of Molluscum contagiosum and to confirm the clinical diagnosis and type of Molluscum cotagiosum virus (MCV) by Polymerase chain reaction (PCR) technique. Patients and methods: The present study was conducted for the period from 1st November 2011 to 30th April 2012 in outpatient clinic of Baquba teaching hospital in Baquba city. One hundred and sixty two patients with molluscum contagiosum were examined and diagnosed clinically and the diagnosis was confirmed by Polymerase chain reaction technique .The lesions of moluscum contagiosum were seen on different sites of the body, age of patients ranged from (1-80 years) with a mean age of 35+_9years . They were 114(70.6%) males and 48(29.4%) females.Results: The results showed that 72 (44.4%) patients of age group (31-40 years), of which 50 (70%) were males and 22 (30%) females, 35 (21.6%) of age group (ten years or less). This study revealed that 56(35%) of patients were illiterate, without statistical significant difference between MC infection and educational levels. In 78% of patients the lesions located on the head and neck, 70% on the right side and in 78% of patients the number of lesions was ≤10 lesions, 70% of patients lived in the urban areas and 30% in rural areas. Eighty five percent (85%) of patients give positive results for MCV, 58.8% of them shows positive results for MCV type 1 and 2 (73.3% MCV-2 and 26.7% MCV-1), while 41.2% shows negative results . Conclusion: We concluded that Molluscum contagiosum was a disease of adult, predominantly males and on the right side of the face and 73.3% of PCR positive results were MCV-2.


Article
Evolution of the Effectiveness of Peremetherin and Trimethoprim/ Slfomethoxazole on Pediculosis Capitit and some Bacteria Isolated from its Complication
تقييم تاثير البيرميثرين وترايمثوبريم مثاكسوزول على قمل الراس وبعض الابكتريا المعزوله من مضاعفاتها

Authors: Burooj Mohammed Razooqi2 بروج محمود رزوقي --- Khudhair Khalf Al-Kayalli خضير خلف الكيالي
Journal: IRAQI JOURNALOF COMMUNITY MEDICINE المجلة العراقية لطب المجتمع ISSN: 16845382 Year: 2017 Volume: 30 Issue: 2 Pages: 79-82
Publisher: Al-Mustansyriah University الجامعة المستنصرية

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Abstract

Abstract: Background:Head lice infestation caused by Pediculus humanus var. Capitis, is the most prevalent human ectoparasitic disease worldwide, head lice are haematophagous, frequent among children 3-11 years. Traditional pharmacological therapies, have focused on 1 or 2 courses of various ovicidal and pediculicidal topical therapies. Objectives: To compare the effectiveness of permetherin and trimethoprim/sulfamethoxazole on 1 or 2 courses of various ovicidal and pediculicidal topical therapies. Methods; Seventy five females patients with pediculosis capitis , their ages ranged from 3 to 60 years. In 40 patients the pediculosis was complicated by secondary bacterial infection. The patients were divided in to three groups, Group 1 :-The patients were treated by 5% permetherin solution . Group 2 :-Was treated by trimethoprim /sulfamethoxazole tablet or solution according to the age .Group 3:- Was treated by combination of 5% permetherin solution and oral trimethoprim /sulfamethoxazole . Swabs were taken from patients with bacterial infection.Results:The study revealed that 23(92%) patients of the first group, was cleared, 20(80%)patients from the second group, also cleared and all the patients in the third group 25(100%). Of those who were complicated by secondary bacterial infection 40(60%), 30(75%) the cultures show bacterial growth. The cultures which were tested by 5% permetherin shows no inhibition zone but those cultures which were tested by trimethoprim /sulphamethoxazol shows significant inhibition zone.Conclusion:It was concluded that permetherin was ineffective as antibacterial agent but it was highly effectivas pediculocidal agent and it was more effective when combined with oral trimethoprim/ sulfamethoxazole.

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