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Article
Some Toxic Effects of Potassium Dichromate on Liver and kidney cortex of adult male rabbits

Author: Mohammed Abdulrazzaq Assi
Journal: Kufa Journal For Veterinary Medical Sciences مجلة الكوفة للعلوم الطبية البيطرية ISSN: 20779798 Year: 2015 Volume: 6 Issue: 1 Pages: 184-190
Publisher: University of Kufa جامعة الكوفة

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Abstract

Twenty four mature adult male rabbits were divided into three groups, each group was involved eight rabbits. The experiment period was reached to six weeks. Administration route of potassium dichromate was orally via drinking water. The first group represented control group. The second treated group was administrated 50mg/kg.Bw. Of potassium dichromate, while the second treated group was administrated 60mg/kg.Bw. Of potassium dichromate. (The present work symptoms on treated groups were appeared as depression), loss of appetite, followed by hyper salivation, lacrimation and diarrhea. The liver tubules of first treated group showed fatty degeneration and intracytoplasmic vacuolization of hepatocyte, while the kidney cortex was revealed glomerulonephritis in some glomeruli, interstitial connective tissue oedema, and degeneration and necrosis in the epithelial lining of proximal and distal convoluted tubules in the first and second treated groups. On the other hand, the liver lobules of rabbit was belonged to second treated group revealed polymorphic nuclear leukocytic infiltration which surrounded the central vein, as well as sever fatty degeneration in the hepatocytes due to effect of potassium dichromate at dose 60ml/kg.B.w, this dose led to sever congestion in the branches of renal vessels in the kidney cortex of rabbits.


Article
The relation-ship between some liver functions and blood parameter in the some coronary heart diseases
العلاقة ما بين وظائف الكبد ومعايير الدم في بعض امراض القلب التاجية

Author: MOHAMMED ABDULRAZZAQ ASSI محمد عبد الرزاق عاصي
Journal: Al-Kufa University Journal for Biology مجلة جامعة الكوفة لعلوم الحياة ISSN: 20738854 23116544 Year: 2013 Volume: 5 Issue: 2 Pages: 193-197
Publisher: University of Kufa جامعة الكوفة

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Abstract

The study was carried out on thirty women and males patients with coronary heart diseases at age (35-70) year old , in the Al-Sader medical city / Al Najaf . the present study was involved blood parameter such as ( Erythrocytes Sedimentation Rate ) and hemoglobin beside the biochemical analysis was done such as cholesterol and triglycerides measurement, also the liver enzymes (GPT and GOT ) level was estimated. Our result was revealed , the increasing in (E.S.R) of males patients (33.3% when compared with (E.S.R) in females which decline into (23.3%),while percent of the (Hb) decrease in female patients more than in the males patients ,were (36.3% , 33.3%) at respectively . the biochemical analysis was appeared elevation of the triglycerides percent in woman patients with cardiac diseases when compared with men patients , the percent was (43.4% , 36.6%) at respectively . from other hand the percentage of cholesterol in some patients men with cardiac disease was (10%) ,while the cholesterol percent in some women patient not significant differences. The present study was noticed increasing in the liver enzymes (GPT) of patients women when compared with patient men were (20%. 13.3%) at respectively.the aim of study to determine relation _ship between some heart diseases and liver functions.

اجريت الدراسة على (30) مريض من الرجال والنساء يعانون من امراض القلب التاجية تراوحت اعمارهم ما بين ( 35-70 ) سنة . انتخب (15) مريض من الرجال و (15) مريض من النساء المرضى اللذين راجعو استشارية امراض القلب في مدينة الصدر الطبية في النجف عام 2011-2012 شملت نتائج الدراسة تنفيذ العديد من معايير الدم مثل قياس خصاب الدم Hb))Hemoglobin , ونسبة ترسب خلايا الدم (erythrocytes sedimentation rate) ( E. S. R) علاوة على اجراء بعض الاختبارات المتعلقة بقياس الدهون الثلاثية Triglyceride ومستوى الكولسترول cholesterol ومستوى انزيمات الكبد (GPT, GOT ). تبين من الدراسة ان نسبة (ESR) لدى المرضى الذكور (33.3%) قياسا مع الاناث (23.3%). في حين انخفض خصاب الدم عند الاناث مقارنة مع المرضى الذكور فكان ( 33.3% 36.3% ) على التوالي . وظهر ارتفاع مستوى نسبة الدهون الثلاثية عند المرضى من الاناث فكانت (36.3%و34.66%) على التوالي. وارتفعت النسبة المئوية للكولسترول لدى مرضى الرجال بنسبة (15%) في حين لن يظهر اي ارتفاع مستوى نسبة الكولسترول جدير بالذكر في المريضات من النساء .اوضحت الدراسة الحالية ارتفاع انزيم الكبد(GPT) عند المريضات مقارنة بالمرضى من الرجال فكان ( 13.3%,20%) على التوالي. الغرض من ذلك للوصول الى علاقة ما بين امراض القلب وبعض وظائف الكبد.

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