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Article
Atherogenic index of plasma (AIP) as a parameter in predicting cardiovascular risk in males compared to the conventional dyslipidemic indices (cholesterol ratios)

Author: Mudhaffar Sami Khazaál
Journal: Karbala Journal of Medicine مجلة كربلاء الطبية ISSN: 19905483 Year: 2013 Volume: 6 Issue: 1 Pages: 1506-1513
Publisher: Kerbala University جامعة كربلاء

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Abstract

Abstractackground: Several indices had been derived from lipid profiles to establish an index for predicting the risk of having coronary event. The atherogenic index of plasma, is a strongly emerging index that is now fulfilling the criteria to be used as a standalone index for cardiac risk stratification.Objectives: To find out whether the atherogenic index of plasma, was superior to the conventional daily used atherogenic indices in predicting cardiac risk. Subjects and methods: A case-control study in which 119 males with an age range of (43-68) years and with acute myocardial infarction together with 97, apparently healthy males of matched age were enrolled. For each participant, a fasting lipid profile done and the following atherogenic indices were calculated: (total cholesterol / high-density lipoproteins), (high-density lipoproteins / low-density lipoproteins), (low-density lipoproteins / high-density lipoproteins), and the (atherogenic index of plasma). The indices were compared in both groups and then in the patients group to figure out which index has yielded the highest sensitivity in predicting the risk of having coronary artery disease.Results:„X All of the atherogenic indices were found to be significantly different upon comparing these indices in both patients and control groups. Where the P value was (0.0001) for (TC/HDL), (HDL/LDL), and (AIP); and it was (0.0026) for (LDL/HDL).„X AIP was found to have the highest sensitivity for predicting atherogenicity among the other atherogenic indices with a value of 84% versus 68%, 73%, and 76% for (TC/HDL), (HDL/LDL) and (LDL/HDL) ratios respectively.Conclusions: The AIP was a superior index for predicting the coronary arterial disease when compared to the most commonly used indices of atherogenicity in every day practice.Keywords: Atherogenic index of plasma, Coronary heart disease, Atherogenic indices.


Article
The Effect of Postural Changes on Spirometric Indices of Upper Airway Obstruction

Authors: Ali Mansoor Al-Ameri --- Ahmad Jumah Mhows --- Mudhaffar Sami Khazaál,
Journal: Karbala Journal of Medicine مجلة كربلاء الطبية ISSN: 19905483 Year: 2013 Volume: 6 Issue: 2 Pages: 1608-1614
Publisher: Kerbala University جامعة كربلاء

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Abstract

the spirometric diagnosis of upper airway obstruction is an important non-invasivetechnique that was validated for the diagnosis of such lesions relying on severalindices that were derived from the flow volume loops of patients.Objectives: Is to find out if postural changes have an effect on spirometric indices of airwayobstruction in healthy subjects and if so, does this merit performing the test in supineposture?Subjects and methods: This study conducted in the department of physiology and medicalphysics/ Kerbala medical college, in which 17 males aged from 18-19 years (18.53 ± 0.51),had BMI of (22.95 ± 2.11 Kg/M2 ), heights of (1.75 ± 0.14 meters) and weights of (70.32 ±6.34 Kgs) were enrolled. The following spirometric data were measured in two different bodypositions (erect versus supine): Forced vital capacity (FVC), Forced inspiratory flow at 50%of vital capacity (FIF50%), Forced expiratory flow at 50% of vital capacity (FEF50%), Forcedexpiratory volume in first second (FEV1), Forced expiratory volume in first 0.5 second (FEV0.5), Peak inspiratory flow (PIF) and Peak expiratory flow (PEF). From these data, thefollowing indices of upper airway obstruction were derived: (FEV1/ FEV0.5, FEV1/ PEF,FEF50%/ FIF50%, and PEF/PIF). These indices were compared with each other in respect totwo body positions.Results:1- All the measured inspiratory and expiratory flow rates were significantly lower in supineposition (p < 0.05).2- Of the four measured indices of upper airway obstruction, only the FEV1/PEF ratioincreased significantly (p < 0.05) by about 27% upon reclining.

Keywords

PFT --- UAO --- FVL --- Body posture --- and OSAS.

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