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THE RELATION OF HYPOKALEMIA TO HYPERTENSIVE AND NON-HYPERTENSIVE ISCHEMIC STROKE

Authors: Haider A. Husain حيدر علي حسين --- Hasan A. Al-Hamadani حسن عزيز الحمداني --- Munther T. Hamzah منذر طاهر حمزة
Journal: IRAQI JOURNAL OF MEDICAL SCIENCES المجلة العراقية للعلوم الطبية ISSN: P16816579,E22244719 Year: 2014 Volume: 12 Issue: 2 Pages: 102-107
Publisher: Al-Nahrain University جامعة النهرين

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Abstract

Background:Several clinical and laboratory observations are consistent with the hypothesis that hypokalemia might be a risk factor for the development of ischemic stroke in humans.Objectives:To evaluate the level of serum potassium in ischemic stroke patients and its relation to non-stroke patients and those with hypertension.Methods:Serum potassium was estimated from one hundred newly discovered first-life ischemic event of acute ischemic stroke patients and one hundred control patients with an attempt to evaluate the its level in ischemic stroke and the relation to hypertension. Normal value of serum potassium in both sexes was considered as 3.5-.5.5 mmol/L.Results:Mean serum potassium level of stroke patients was significantly lower than that of control group (3.89±0.67 versus 4.19±0.56, p=0.0001). Hypokalemia was found in 23 (23%) patients with stroke compared to 7 (7%) of the control group. The Mean serum potassium in hypertensive patients was significantly lower than those without hypertension (3.91 ±0.65 versus 4.2 ±0.54). The mean serum potassium for hypertensive stroke patients was significantly lower than non-hypertensive stroke patients (3.79±0.78 versus 4.26±0.72), while there was no significant difference among the control hypertensive and non-hypertensive subjects (4.05±0.57 versus 4.43±.40).Conclusions:Serum potassium should be taken in consideration as low levels are significantly associated with ischemic stroke with hypertension.Keywords:Serum Potassium, ischemic stroke


Article
THE SIGNIFICANCE OF HYPERGLYCEMIA IN THE FIRST 24 HOURS OF STROKE

Authors: Muhanad A. Kadhim مهند احمد كاظم --- Hasan A. Al-Hamadani حسن عزيز الححمداني --- Munther T. Hamzah منذر طاهر حمزة
Journal: IRAQI JOURNAL OF MEDICAL SCIENCES المجلة العراقية للعلوم الطبية ISSN: P16816579,E22244719 Year: 2016 Volume: 14 Issue: 1 Pages: 88-92
Publisher: Al-Nahrain University جامعة النهرين

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Abstract

Background:The study focused on acute stage of stroke patients and investigated which parameters of glucose in acute phase of stroke are significant in nondiabetic stroke patients.Objective:To evaluate hyperglycaemia in acute phase of stroke.Methods:Cross sectional study was conducted in Al-Imamain Al-Kadhimiyan Medical City in Baghdad city from October 2013 to September 2014. We studied glucose levels and glycosylated haemoglobin in 100 consecutive patients with acute stroke admitted within 24 hours after onset of symptoms.Results:One hundred consecutive patients (65 men and 35 women ) were included in this study, 76 patients with diagnosis of ischemic stroke and 18 of them with diagnosis of intracerebral haemorrhage and 6 patients with transient ischemic attack Hyperglycemia was found in 44 patient. High glycosylated haemoglobin levels were found in 29 patients, 16 patients of them have history of diabetes. The other 13 with elevated glycosylated haemoglobin levels were considered as prediabetes. The remaining 15 patients had normal glycosylated haemoglobin.Conclusion:There is significant relationship between idiopathic hyperglycemia and prediabetes with acute stroke.Keywords:Stroke, diabetes mellitus, hyperglycaemia


Article
QUANTIFICATION OF PAIN THRESHOLD IN PARKINSON’S DISEASE

Authors: Aqeel K Hatim عقيل كريم حاتم --- Munther T Hamzah منذر طاهر حمزة --- Hasan A Hasan حسن عزيز حسن --- Zaki N Hasan زكي نوح حسن
Journal: IRAQI JOURNAL OF MEDICAL SCIENCES المجلة العراقية للعلوم الطبية ISSN: P16816579,E22244719 Year: 2012 Volume: 10 Issue: 1 Pages: 83-86
Publisher: Al-Nahrain University جامعة النهرين

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Abstract

BackgroundParkinson's disease (PD) is the second most common degenerative neurologic disorder after Alzheimer’s disease. Pain is one of the major clinical symptoms of Parkinson's disease, occurring in 50-83% of patients. Pathways mediating pain are complex and include basal ganglia and thalamocortical-basalganglia circuits.ObjectiveTo quantitatively assess pain perception in Parkinson disease patients, by determining pain threshold in patients with and without pain through using electrical stimulation.MethodsA cross sectional observational study recruiting 18 patients with a clinical diagnosis of Parkinson disease and healthy controls from the neurologic unit in Al-Kadhimiya Teaching Hospital in Baghdad; between May 2010 to Jan 2011. There were 13 men and 5 women with a mean age of (66.5 ± 10.2 years). The control group includes 18 healthy subjects, [12 males/ 8 females] with a mean age of 56.6±6.74 years. Quantitative sensory testing was carried at the neurophysiology laboratory in Al-Kadhimiya hospital; using bipolar stimulating electrodes on the forearm, index finger, mid leg, and big toe.ResultsFourteen Out of 18 patients (77.7%) reported pain, while 4 (22.3%) had no pain. There was a highly significant statistical difference in electrical perception between the affected and unaffected side, and between Parkinson disease patients and the controls. There was no statistically significant difference between males and females [p =0.8248], and between patients with and those without pain [p =0.3279]. And between upper and lower limbs on the affected side [p =0.1412], and body side involvement whether right or left in both the patients and controls.ConclusionChronic pain is present in 77.7% of Parkinson disease. Patients with Parkinson disease had lower pain threshold compared to controls. The affected side had lower pain threshold. The left or right body side and gender had no effect on pain threshold.Key worldsParkinson disease, Pain

Keywords

Parkinson disease --- Pain

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