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Article
Evaluation the relation of TNF-alpha in aborted women who suffer from bacterial vaginitis

Authors: Nadya I. Salih --- Maisaloon F. Hassan
Journal: The Medical Journal of Tikrit University المجلة الطبية لجامعة تكريت ISSN: 18131638 Year: 2018 Volume: 24 Issue: 2 Pages: 95-103
Publisher: Tikrit University جامعة تكريت

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Abstract

ABSTRACT: Background The role of infectious diseases in recurrent miscarriage is not clarified yet, but proposed an incidence of 0.5–5%. There are some candidate infectious diseases such as Listeria monocytogenes, Toxoplasma gondii, rubella, herpes simplex virus (HSV), measles, cytomegalovirus, and coxsackie viruses. Aim: This study was aimed at evaluation of the relation of TNF-α level in aborted women infected with bacterial vaginitis. Material and Method A cross sectional study was carried out in Kirkuk city from the beginning of February 2018 to the end of May 2018, deep vaginal swab was collected from 100 women with recurrent abortion and 50 pregnant women (as control group) that belonged to different geographical areas in Kirkuk city and admitted to Kirkuk General Hospital. The swabs samples were cultured on blood agar and MacConkey agar for 24 hour and secondary cultures were done for resulted culture for isolate specific bacteria. Five ml of blood was collected from each women enrolled in this study for TNF-α test using ELISA technique. Results The study showed that 57% of women with recurrent abortion have positive high vaginal swab (HVS) culture comparing with 48% of pregnant women (control group). The current study showed that 86% of women had aborted in the 1st trimester of pregnancy and the least rate of abortion was in the 3rd trimester. The study showed that 52.25% of aborted women were belonged to the age group 27-36 years and highest rate of isolated bacteria from the HVS culture of aborted women was S. aureus (45.61%) while Proteus spp. was not isolated from aborted women. The study found that the highest mean of TNF-α level was denoted among women with abortion comparing with the control group (26.79±9.4 v.s 9.236±0.6 pg/ml) with highly significant relation of TNF-α level with abortion. The study showed that the highest TNF-α mean levels was recorded among women who aborted in the 1st trimester (28.75±8.76 pg/ml) and the lowest mean was noted among the 3rd trimester aborted women with highly significant relation among the groups. Conclusions It was concluded that the there was a highly significant relation of TNF-α level with abortion specially with women suffered from bacterial vaginosis.

Keywords

TNF-α --- Abortion --- Kirkuk --- Bacterial vaginitis


Article
Hepatitis C virus infection and abortion among pregnant women in Mosul city
عدوى فيروس التهاب الكبد C والإجهاض بين النساء الحوامل في مدينة الموصل

Authors: Sumaya T. Saihood --- Nadya I. Salih --- Israa H. Saadoon
Journal: The Medical Journal of Tikrit University المجلة الطبية لجامعة تكريت ISSN: 18131638 Year: 2008 Volume: 1 Issue: 141 Pages: 161-164
Publisher: Tikrit University جامعة تكريت

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Abstract

Infection with HCV is a major public health problem and is of particular concern duringpregnancy. Identification of transmission risk factors is essential for the development ofappropriate interventions. The aim of this study was to evaluate infection with HCV in pregnantwomen and to identify the correlation between HCV infection and abortion. The current studyincluded 875 pregnant women attended to three hospitals in Mosul City (Al-Batool, Al-Khansaa,and General Mosul Hospital) during the period from the beginning of July 2007 to the end ofSeptember 2007. The study revealed that infection with hepatitis C virus (HCV) was found in 45out of 875 pregnant women (5.14 %). There was significant correlation between HCV infectionand abortion. The risk of HCV infection increased with increasing number of abortions.

عدوى فيروس (سي) هو مشكلة صحية عامة رئيسية ومصدر قلق خاص خلال الحمل. تحديد عوامل الخطر انتقال أمر أساسي من أجل تطوير التدخلات المناسبة. وكان الهدف من هذه الدراسة لتقييم الإصابة بفيروس الكبد الوبائي في الحوامل نساء والتعرف على العلاقة بين فيروس التهاب الكبد الوبائي، والإجهاض. الدراسة الحالية وحضر وشملت 875 امرأة حامل الى ثلاثة مستشفيات في مدينة الموصل (سورة بتول، الخنساء، والجنرال مستشفى الموصل) خلال الفترة من بداية يوليو 2007 الى نهاية عام سبتمبر 2007. وكشفت الدراسة التي تم العثور عليها مع عدوى فيروس التهاب الكبد الوبائي (سي) في 45 من أصل 875 امرأة حامل (5.14٪). كان هناك ارتباط كبير بين فيروس التهاب الكبد الوبائي والإجهاض. تزيد من خطر الإصابة بعدوى هذا الفيروس مع تزايد عدد حالات الإجهاض.


Article
Evaluation of the immune response toward Neisseria meningitidis in displaced people receiving A.C.W.Y-meningococcal vaccine

Authors: Nadya I. Salih --- Thekra A. Hamada --- Eapak Q. Hasan
Journal: The Medical Journal of Tikrit University المجلة الطبية لجامعة تكريت ISSN: 18131638 Year: 2019 Volume: 25 Issue: 1 Pages: 44-53
Publisher: Tikrit University جامعة تكريت

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Abstract

ABSTRACT: Background Meningococcal vaccine refers to any of the vaccines are used to prevent infection by Neisseria meningitidis. Patients & Methods: The present study was carried out from 15th of January 2018 to 15th of June 2018. The number of previously vaccinated for N. meningitidis individuals under study was 68 displaced individuals whose ages were between 5-60 years old. These individuals were living in Laylan refugee camps. The control group who were matched to the patients studied, included 22 blood donors. The blood was collected from each individual enrolled in this study for estimation of anti-meningococcal group ACWY antibodies (IgG, IgM and IgA) level by ELISA technique. The Results: The study showed that the mean of anti-meningococcal IgA-Abs in previously vaccinated persons (0.116 pg/ml), which was higher than that of the control group (0.014 pg/ml), the highest mean of anti-meningococcal IgM-Abs was occurred in previously vaccinated persons (0.2962 IU/ml) comparing with the control group (0.0064 IU/ml) and the highest rate of IgG positive result was (5.88%) present in previously vaccinated persons comparing with the control. The study showed that there was no significant relation of anti-meningococcal antibodies with sex and the highest mean level of anti-meningococcal IgM was recorded among males. This study showed that there was no significant relation of anti-meningococcal antibodies with age and the highest mean level of anti-meningococcal IgA was recorded among the age group 5-16 years. The study showed that the highest mean level of anti-meningococcal IgA, IgM and IgG antibodies were observed among the group of 1-2 months after vaccination (0.1341, 0.3089 and 0.0483 pg/ml respectively).

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