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Article
CT angiographic determination of most frequent anatomic variations of coronary arteries in Erbil population

Authors: Zana Mustafa Mahmood --- Nasih Mohsin Ahmed --- Nali Abdulkader Maaruf
Journal: Zanco Journal of Medical Sciences مجلة زانكو للعلوم الطبية ISSN: 19955588/19955596 Year: 2019 Volume: 23 Issue: 1 Pages: 19-27
Publisher: Hawler Medical Univeristy جامعة هولير الطبية

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Abstract

Background and objective: Computed tomography angiography is one of the best methods for knowing the detailed anatomy of coronary arteries and can successfully detect any variation of coronary arteries. Anatomic variations of coronary arteries have not been studied among Erbil population which is mostly inhabited by Kurds. This study was conducted to compare the incidence of the anatomic variations of coronary arteries in Erbil population with international standards.Methods: Variations of coronary arteries were retrospectively studied by using computed tomography angiography of 412 cases (214 males 198 females) with mean age 51.5 ± 13.5 years (mean ± SD) who underwent this procedure on suspicion of coronary artery disease. The main indication was chest pain in patients with low to intermediate probability of ischemic heart disease. The present study was carried out in the Department of Radiology, Surgical Specialty Hospital/Cardiac Center in Erbil city. Results: The right coronary artery was dominant in 86.4% of cases, while the left main coronary artery was dominant in 10.92% of cases. Co-dominance was observed in 2.67% of cases, and Double Ostia of right aortic sinus was observed in 25% of cases. Long left main coronary artery was observed in 10.68 % of cases. Myocardial bridging was observed in 7.04% of cases. Other variations were also observed, and their prevalence was recorded.Conclusion: Variations of coronary arteries among Erbil population were recorded and were near to the international standards.


Article
Effect of Aspartame on the Rat’s Thyroid Gland: A histological and Morphometrical Study
تأثير الأسبرتام على الغدة الدرقية لذكور الجرذان البيضاء دراسة نسيجية وشكلية

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Abstract

Background: The aspartame is a synthetic sweetener has been used for many purposes as an anti-inflammatory agent, antioxidants and hepato protective, its metabolites can be toxic to many organs and several studies on laboratory animals have been made to verify aspartames toxicity which can cause harmful effect after administration for long duration at a dose of 150 mg/kg body weight.Objective: To evaluate the effect of aspartame on morphometric and histopathological changes of the rat’s thyroid gland, since the aspartame sweetener is widely used worldwide. Patients and Methods: Fifty adult Wister albino rats were used and divided randomly into two groups. The treated group received 150 mg/kg aspartame orally daily after dissolving it in 2cc distilled water and the control group received 2cc distilled water daily orally for eight weeks.Results: Histological examination of aspartame-treated group showed loss of normal architecture of the thyroid gland. morphometrical measurement showed many follicles were small in size and others had disrupted wall and detached cells in their lumens, there was significant increase in the height of cells and number of follicles with decrease inwidth of the cells.Conclusion: Administration of aspartame at a dose 150 mg/kg had a significant effect on both histologic and morphometrical structure of the adult rat’sthyroid gland.

خلفية الدراسة: تم استخدام الأسبارتام فى التحلية الاصطناعية لأغراض كثيرة كعامل مضاد للالتهابات ،مضادات الأكسدة، وحافظة للكبد، يمكن عناصره ان تكون سامة على الجسم والعديد من الدراسات اجريت على الحيوانات المختبرية لتحقق سمية الاسبارتام و التي يكون تاثيرها ضارا بعد تناوله لمدة طويلة بجرعة 150 ملغم / كغم من وزن الجسم.اهداف الدراسة : لمعرفة تأثير مادة الاسبارتم على الغدة الدرقية للذكور الجرذان وتغيرات القياسات الشكلية النسيجية.المرضى والطرائق : أجريت الدراسة على خمسين جردا , قسمت الجردان الى مجموعتين (المجموعة الأولى مجموعة السيطرة مؤلفة من 10 جردا تلقت ماء المقطر 2 سس) و(المجموعة الثانية كانت مجموعة الاختبار مؤلفة من 40جردا تلقت الأسبرتام بجرعة150 مج / كجيوميا) بعد اذابة فى الماء المقطر (2 سس) لمدة ثمانية أسابيع.النتائج: اوضحت نتائج الفحص النسيجي باستخدام المجهر الضوئي فقدان في البناء التركيبى للغدة الدرقية كما وجد العدبد من الحويصلات الصغيرة الحجم مع عدم اكتمال فى جدار العديد من حويصلات الغدة الدرقية وظهور خلايا منزوعة بتجويفها أوضحت القياسات الشكلية النسيجية انخفاض مميز فى مساحات الحويصلات و محتواها من المادة اللزجة و عرض الخلايا و زيادة الحويصلات و ارتفاع الخلايا المبطنة لهذه الحويصلات لمجموعة الاختبار مقارنتا بمجموعة السيطرة.الاستنتاجات: ان استخدام الأسبارتام بجرعة 10 ملغم/ كغم يسبب تأثيرات كبيرة على التغيرات النسيجية و القياسات الشكلية للغدة الدرقية.

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