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Evaluation of treatment of intra-bony defects with a mixture of β-tricalcium phosphate - hydroxyapatite granules and oily calcium hydroxide suspension

Author: Raed A. Badiea
Journal: Journal of baghdad college of dentistry مجلة كلية طب الاسنان بغداد ISSN: 16800087 Year: 2013 Volume: 25 Issue: 3 Pages: 103-109
Publisher: Baghdad University جامعة بغداد

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Abstract

Background: An oily calcium hydroxide formulation proved over the last years to be highly efficient in promotingbone regeneration in closed defects as periapical lesions, cysts, or post-extraction defects. The aim of the presentstudy is the assessment of the outcome of treatment of deep intrabony periodontal defects with an Open FlapDebridement) (OFD) + combination of {(30% Hydroxyapatite HAp + 70% β-Tricalcium Phosphate granules mixed withan Oily Calcium Hydroxide Suspension (OCHS )} and compare the results with {(OFD) alone)}. The combination ofOCHS& TCP was used in humans with a sort of positive results, and more conduction of studies was recommended.Material and method: The sample of this study composed of sixteen patients; each had at least two intrabony defectteeth. For each patient, one tooth was treated by OFD only (control group 16 teeth) and the other teeth (studygroup 16 teeth) were treated with OFD + a mixture of (OSTEON II- Korea) granules comprise of (30% HydroxyapatiteHAp + 70% β-Tricalcium Phosphate) and OCHS (Osteoinductal®, Osteoinductal GmbH., Muenchen, Germany). Theclinical parameters that were measured and recorded included (Plaque index PLI, Gingival index (GI), Gingivalrecession(GR) , Bleeding on probing (BOP), probing pocket depth (PPD), clinical attachment level (CAL) andradiographical width & depth of the bony defect. These parameters were recorded before treatment (base line) &six months after the treatment.Results: The results after treatment revealed a highly significant reduction in all of the parameters except the PLI inboth study & control groups compared to baseline (p < 0.001). The clinical results were indicated that the studygroup showed significant reductions of PPD and CAL mean values more than improvements obtained by the controlgroup with significant difference (p < 0.05).Conclusions: An excellent postoperative improvement in clinical parameters was noticed in the study group morethan control group and the differences were significant. Thus the present study has revealed that the treatmentmodality of OFD + a combination of granules comprise of (30% Hydroxyapatite HAp + 70% β-Tricalcium Phosphate)mixed with oily Calcium Hydroxide suspension is successful, predictable and more beneficial than (open flapdebridement) (OFD) alone in the treatment of deep intrabony periodontal defects


Article
Efficacy of Intra-Pocket Application of Two Antimicrobial Agents as an Adjunct to Mechanotherapy of Chronic Periodontitis (a Comparative Study)

Author: Raed A. Badiea
Journal: Tikrit Journal for Dental Sciences مجلة تكريت لعلوم طب الاسنان ISSN: 20731213 Year: 2014 Volume: 3 Issue: 1 Pages: 83-93
Publisher: Tikrit University جامعة تكريت

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Abstract

Numerous studies have been performed to evaluate the effectiveness of the use of locally delivered antimicrobials as an adjunct to mechanotherapy in treatment of chronic periodontitis. Some studies were resulted in improved clinical outcomes and others were not. The aim of this study is evaluation of the efficacy and safety of subgingival application of a (10 mg metronidazole gel), (1% chlorhexidine collagen gel) and (CHLOSITE® GHIMAS, Italy) gel which is a combination of two chlorhexidine formulations: 0.5% chlorhexidine digluconate and 1.0% chlorhexidine dihydrochloride), as an adjunct to mechanical treatment (scaling and root planing) (SRP) of chronic periodontitis. A total of 120 sites from 15 patients with age range of (24-55 years), who had periodontal pockets measuring 5-9 mm and had been diagnosed as chronic periodontitis cases, were selected for the study. The 4-quadrant split-mouth design was used in this study. The pocket sites in each patient were randomly assigned to 4 groups (30 sites for each): (Group A) GA=(SRP) only. (Group B) GB=(SRP) + 10 mg metronidazole gel. (Group C) GC=(SRP) + 1% chlorhexidine collagen gel. (Group D) GD=(SRP) + CHLOSITE® Clinical parameters including (plaque index PI), (gingival index GI), (gingival bleeding index) GBI, (probing pocket depth PPD) & (clinical attachment level CAL) were measured and recorded at baseline before any treatment at (day 0) then the treatment was performed at the same day, The clinical parameters were also recorded at (day 30) & (day 90), in the selected sites of the four groups. The results of this study obviously showed a statistically significant reduction of all clinical parameters in all groups at (day 30 & day 90) from the base line (day 0). GD=(SRP) + CHLOSITE® revealed a reduction of the clinical parameters than groups (A, B and C) and the differences were highly statistically significant

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