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The Role of C-Reactive Protein in Diagnosis of Neonatal Sepsis

Author: Sabah Hassan Alatwani
Journal: Medical Journal of Babylon مجلة بابل الطبية ISSN: 1812156X 23126760 Year: 2014 Volume: 11 Issue: 4 Pages: 906-911
Publisher: Babylon University جامعة بابل


Across-sectional study was conducted in Amara city hospitals during a period from March 2013 till February 2014. The study sample includes 88 neonates (43 with clinical features of septicemia and 45 neonates who were normal). Blood culture and C-reactive protein tests were done for all neonates. In comparison with the result of blood culture, the C-reactive protein test was found that 42 out of 45 neonates as true negatives, the remaining 3 neonates showing sepsis and were considered as false negative. While 32 out of 43 neonates were considered as true positive. Finally the study showed that the sensitivity of C-reactive protein examination was 74.4%, specificity was 93% , positive predictive value was 91% and negative predictive value was 79%, so the C-reactive protein had important role in detection of the neonatal sepsis and consider an supportive tool to gold standard (blood culture) test for diagnosis of septicemia.

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