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Expression of Syndecan 1 on Periodontium treated with Topical Application of Aloe-Vera

Authors: Sabrin Sami Abed صابرين سامي عبد --- Athra'a Y. Al-Hijazi عذراء يحيى الحجازي
Journal: Journal of baghdad college of dentistry مجلة كلية طب الاسنان بغداد ISSN: 16800087 Year: 2016 Volume: 28 Issue: 3 Pages: 82-86
Publisher: Baghdad University جامعة بغداد


Background: Periodontium mainly exposed to injury by trauma or pathologic diseases, Aloe vera is a plant has manybasic ingredients in its extracted gel that acts as wound healing accelerator in addition to that it's safe, andeconomical and without recordable of side effect. This study aimed is to evaluate the effect of topical application ofAloe vera on expression of syndecan -1 by periodontium tissue.Materials and methods: Thirty six male Albino rats were subjected for periodontium defect by electric scaler on thedistal sides of both lower anterior teeth. The animals divided into two groups; control group (without treatment) andthe experimental group treated with 1μLAloe vera gel/normal saline. Periodontal healing was examined at periods(3, 7, 14 days) for immunohistochemical localization of syndecan 1.Results: Immunohistochemical examination of this study revealed that the aloe vera treatment increase expression ofsyndecan 1 by epithelial cell, osteoblasts, fibroblast, stromal cells and with highly significant differences incomparison with control and saline.Conclusion: Aloe vera gel may affect the expression of syndecan 1 which seems to play a role in periodontiumhealing.


Aloe vera --- periodontium --- syndecans

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