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The role of von Willebrand factor in determining the risk of ischemic stroke in Hawler city: a case-control study
دور عامل فون ويلبراند في تحديد خطر الإصابة بالسكتة الدماغية في مدينة هولير: دراسة الحالات و الشواهد

Authors: Salar Adnan Ahmed --- Sazgar Anwar Hameed
Journal: Zanco Journal of Medical Sciences مجلة زانكو للعلوم الطبية ISSN: 19955588/19955596 Year: 2018 Volume: 22 Issue: 1 Pages: 120-125
Publisher: Hawler Medical Univeristy جامعة هولير الطبية

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Abstract

Background and objective: Ischemic stroke is classically characterized as a neurological deficit attributed to an acute focal injury of the central nervous system by a vascular cause, it occurs as a result of obstruction by a blood clot (thrombus) or plugs within a blood vessel supplying blood to the brain. In this study, we investigated the association of von Willebrand factor-antigen and serum lipids with ischemic stroke.Methods: The following retrospective study was conducted on 138 participants; 88 patients with ischemic stroke and 50 healthy controls.Results: In crude analyses, Plasma von Willebrand factor antigen, fasting serum Total cholesterol, Triglycerides and LDL-C were significantly higher in patients with ischemic stroke than in controls (P <0.001, P <0.001, P = 0.003, P <0.001, respectively), while the difference in the level of serum HDL-C between patients with ischemic stroke and control was significantly lower (P = 0.023).Conclusion: These data suggest that von Willebrand factor, total cholesterol, triglycerides, LDL-C and HDL-C gives some contribution to stroke risk even in the elderly and that von Willebrand factor antigen and lipid profile assessment must be taken into account in estimating the individual risks of stroke.


Article
Evaluation of some micronutrients in patients infected with Giardia lamblia in Hawler city
تقييم بعض المغذيات الدقيقة في مرضى الجيارديا اللامبلية في مدينة هولير

Authors: Sharmeen Qadir Faqi --- Salar Adnan Ahmed --- Hawre Mustafa bakre
Journal: Zanco Journal of Medical Sciences مجلة زانكو للعلوم الطبية ISSN: 19955588/19955596 Year: 2016 Volume: 20 Issue: 1 Pages: 1228-1232
Publisher: Hawler Medical Univeristy جامعة هولير الطبية

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Abstract

Background and objective: The micro aerophilic flagellated protozoan parasite, Giardia lamblia, is the most common intestinal pathogen infecting human and a major diarrheal disease found throughout the world. It can cause acute or chronic diarrhea contributing to nutritional status, growth, and intellectual function. This prospective study evaluated the association between giardiasis and blood minerals disorders in Hawler city. Methods: The present study was carried out at the College of Medicine, Hawler Medical University, via collaborating study between the Department of Biochemistry and the Department of Microbiology. The study was carried out on 50 patients with giardiasis and 65 age and sex matched healthy controls. Examination of fecal samples for detection of Giardia cyst and/or trophozoite was carried out using the direct wet smear, while serum zinc, iron and copper levels were measured for both groups spectrophotometrically using commercial diagnostics kits. Results: The levels of serum zinc and iron in patients infected with Giardia lamblia were significantly lower (P <0.01) compared to normal healthy control, while the differences in the level of serum copper was significantly higher (P <0.01).Conclusion: : In the frame of this work we delineate that Giardia lamblia infection had a significant effect on serum trace elements reflected by, significant decrease in serum zinc and iron levels, whereas the level of copper increased too in a statistically significant manner.

Keywords

Giardia lamblia --- Parasite --- Micronutrients --- Zinc --- Iron --- Copper

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