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Assessment of serum testosterone in females with acne vulgaris in Erbil city
تقييم هرمون التستوستيرون في المصل عند الإناث المصابات بحب الشباب في مدينة أربيل

Authors: Fatin Qaraney Fattah --- Yousif Bahaaddin Ahmed
Journal: Zanco Journal of Medical Sciences مجلة زانكو للعلوم الطبية ISSN: 19955588/19955596 Year: 2016 Volume: 20 Issue: 1 Pages: 1249-1253
Publisher: Hawler Medical Univeristy جامعة هولير الطبية

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Abstract

Background and objective: Acne vulgaris is a chronic inflammatory disease of the pilosebaceous units, characterized by comedones, papules, pustules and nodules. Acne affects primarily the face, neck, upper trunk. Acne typically begins at puberty and it is often the first sign of increased sex hormone production. In all women with acne the possibility of hyperandrogenic state should be considered. The aim of this study was to determine the relationship between abnormal testosterone level and other virilising signs in young females with acne vulgaris. Methods: This case-control study was carried out from April 2013 to January 2014 in the consultation Department of Dermatology and Venereology at Rizgary Teaching Hospital in Erbil city. Sixty females were considered group A (case group with acne) and 60 females were considered as group B ( control group) without acne. Results: The mean±SD serum testosterone level was significantly higher among patients with acne compared to the control group (0.51 ng/ml ± 0.27 compared to 0.31 ng/ml ± 0.12, P ˂0.05). Irregular cycle was found in 28 cases (46.6%). Conclusion: The study showed presence of a significant association between serum testosterone level and acne vulgaris in female patients.


Article
Association of subclinical hypothyroidism with metabolic syndrome in females of reproductive age

Authors: Muhammad Sadradin Mahmood --- Yousif Bahaaddin Ahmed
Journal: Zanco Journal of Medical Sciences مجلة زانكو للعلوم الطبية ISSN: 19955588/19955596 Year: 2019 Volume: 23 Issue: 3 Pages: 338-344
Publisher: Hawler Medical Univeristy جامعة هولير الطبية

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Abstract

Background and objective: The association of metabolic syndrome and subclinical hypothyroidism is a matter of debate. Both confer an increased risk for cardiovascular disease and type 2 diabetes mellitus, and previous studies showed overlap between features of both conditions. This study aimed to evaluate the association of subclinical hypothyroidism with metabolic syndrome in young women.Methods: This case control study was conducted in the internal medicine consultation department of Rizgary Teaching Hospital Erbil, Iraq, from May 2017 to May 2018. Sixty eight consecutive women with the metabolic syndrome as per the Harmonizing definition were compared to 95 age matched women with no metabolic syndrome as a control group. Detailed history and physical examination with blood pressure and waist circumferences recorded and appropriate fasting blood samples were tested for plasma glucose, lipid profile, TSH, free T3, and free T4.Results: Subclinical hypothyroidism was present in 10 (14.7%) of the 68 women with metabolic syndrome and four women (4.2%) of the 95 control group with a significant difference (P = 0.018). Central obesity, hypertriglyceridemia, and low levels of high density lipoprotein were present in 9 (17.3%), 9 (23.1%), and 10 (16.4%) women with subclinical hypothyroidism with a significant difference for each association (P = 0.013, 0.001 and 0.006, respectively).Conclusion: There is a significant association between subclinical hypothyroidism and metabolic syndrome in young women.

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