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Effect of Rhus coriaria extract on wound healing potential in Sprague Dawley rats
تأثير مستخلص Rhus coriaria على احتمال التئام الجروح في فئران سبراج داولي

Author: Zahra Abdulqader Amin
Journal: Zanco Journal of Medical Sciences مجلة زانكو للعلوم الطبية ISSN: 19955588/19955596 Year: 2018 Volume: 22 Issue: 1 Pages: 89-95
Publisher: Hawler Medical Univeristy جامعة هولير الطبية

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Abstract

Background and objective: Rhus coriaria, a well-known spice grown in the Kurdistan region of Iraq, commonly known in the Middle East Region by (Sumac), is reported to enclose many medical benefits. This study assessed the effects of topical application of Rhus coriaria extract on the rate of wound closure, the Hydroxyproline (HXP) and Nitric Oxide (NO) levels were measured using the healed skin tissue homogenate the elemental composition of the plant was screened.Methods: Adult male Sprague Dawley rats were topically treated with 0.2 mL of the vehicle (gum accacia), Intrasite gel (positive control), 100 and 200 mg/kg of Rhus coriaria extract.Results: Wounds dressed with the extract and Intrasite gel healed significantly earlier than those with the vehicle. The high content of HXP and NO proves that the effect of Rhus coriaria extract on an excision wound model was significantly higher than that of the vehicle itself. The highest mineral contents were in Potassium, Calcium, Phosphorus, Magnesium and the extract was rich in energy content.Conclusion: The current study concluded that Rhus coriaria showed high potential in wound healing activity.


Article
The frequency of autoimmune thyroid disorders in patients with thyroid dysfunction in Erbil city
تواتر اضطرابات الغدة الدرقية الذاتية المناعة في مرضى الغدة الدرقية في مدينة أربيل

Authors: Sanar Ilyas Kamal --- Rawaz Dalzar Tawfeeq --- Zahra Abdulqader Amin
Journal: Zanco Journal of Medical Sciences مجلة زانكو للعلوم الطبية ISSN: 19955588/19955596 Year: 2018 Volume: 22 Issue: 3 Pages: 372-376
Publisher: Hawler Medical Univeristy جامعة هولير الطبية

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Abstract

Background and objective: Thyroid disorders are one of the most frequent pathologies found in the general population, but identifying thyroid disease can be clinically challenging because subclinical thyroid dysfunction and autoimmune thyroiditis are often asymptomatic and usually diagnosed biochemically. This study aimed to distinguish the autoimmune thyroid diseases from other forms of thyroid dysfunctions in patients admitted to PAR hospital in Erbil city.Methods: blood was withdrawn from healthy subjects, and unhealthy patients suffer from thyroid dysfunction, their age and gender were recorded, and their blood serum were subjected to test the thyroid function antibodies including triiodothyronine T3, thyroxin T4, and thyroid stimulating hormone TSH. Also, autoimmune antibodies were tested including anti-thyroglobulin antibody (anti-TGA) and thyroperoxidase antibody (TPO antibodies).Results: no significant differences were shown in T3 levels while contrary highly significant differences were shown in T4, TSH anti-TGA and anti-TPO levels between healthy subjects and unhealthy patients groups. The percentages of autoimmune thyroid diseases were (45.2%) as compared to the other forms of thyroid dysfunctions (54.8%). Most of the patients were females in the age group 30-39 years.Conclusion: In Erbil city population/PAR hospital the prevalence of autoimmune thyroid diseases were more frequent among other thyroid diseases collectively. It is mostly found in females rather than males within the age group 30-39 years.

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