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Effects of diabetes mellitus types II on salivary flow rate and some salivary parameters (total protein, glucose, and amylase) in Erbil city

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Abstract

Background: The concentration of some components of saliva may be associated with certain systemic illnesses,reflecting the hormonal, immunological, neurological, emotional, nutritional and metabolic states of the patient. Theaim of this work was to assess salivary flow rate, and to evaluate saliva samples for levels of salivary total protein,glucose, and alpha amylase, in diabetics type II and healthy subject in both genders.Subjects and methods: Unstimulated salivary flow rate, salivary total protein, glucose, and amylase were measuredin 90 subjects, 60 with diabetes mellitus type II (30 controlled and 30 uncontrolled diabetic patients) and in 30 healthysubjects.Results: Significant difference in salivary flow rate in diabetic patient when compared with healthy subject. Thefinding showed no significant differences between salivary total proteins in all groups. Significant difference in salivaryglucose and amylase concentration was found between the healthy subjects and type 2 diabetic patients.According to the gender, there were only significant differences between male and female in salivary flow rate forhealthy subjectsConclusions: Patients with type 2 diabetes mellitus have higher concentration of salivary glucose and lower value ofsalivary flow rate and amylase. No significant difference was seen in protein value in all groups

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2012 (1)