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Article
Effect of Diabetes mellitus Type 2 on Pituitary Gland Hormones (FSH, LH) in Men and Women in Iraq

Authors: Jawad Al-Qaisi --- Zyad Hussein
Journal: Al-Nahrain Journal of Science مجلة النهرين للعلوم ISSN: (print)26635453,(online)26635461 Year: 2012 Volume: 15 Issue: 3 Pages: 75-79
Publisher: Al-Nahrain University جامعة النهرين

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Abstract

The objective of this cross sectional study was to assess the effect of diabetes mellitus (DM) type2 on pituitary gland hormones (FSH and LH) in both men and women. This study comprised a total of (108) subjects out of which (50) were normal and the rest (58) were diabetic since more than 5 years. Fasting blood sugar, HbA1c, LH and FSH were measured in blood samples. The results obtained indicated a significant reduction of serum LH, FSH in women with DM comparison to non diabetics and a significant reduction of serum LH and FSH in men with DM comparison to non diabetics. Conclusion: the data from this study show reduction in serum FSH and LH of diabetic patients of both sex compared to healthy individuals

ان هذه الدراسة النوعية لتقيم تأثير مرض السكر من النوع الثاني على هرموني الغده النخامية (FSH,LH) عند كلا الجنسين الرجال والنساء. اجريت الدراسة على مجموعة من الاشخاص يبلغ عددهم (108) وكان منهم (50) شخص من الاصحاء، لا يعانون من الامراض، و(58) مصاب بمرض السكر من النوع الثاني لاكثر من (5) سنوات. سحبت عينات من الدم من هؤلاء الاشخاص وقيست مستويات كل من (FBG ,c1HbA ,FSH ,LH). ودلت النتائج التي تم التوصل اليها الى نقصان معنوي في مستوى هرموني الـ (FSH ,LH) عند النساء المصابات بمرض السكر من النوع الثاني مقارنه بالاصحاء، وكذالك نقصان معنوي في هرموني الـ (LH ,FSH) عند الرجال المصابين بمرض السكر من النوع الثاني مقارنة بالاصحاء.

Keywords

diabetes mellitus --- HbA1c --- LH --- FSH


Article
Study of Some Hematological Parameters and Determination of Glysated Hemoglobin in β-Thalassemia

Authors: Zyad Hussein Jawad AL-Qaisi --- Wasan A.K. M. --- Zaineb Moneb Al-Rubae
Journal: journal of the college of basic education مجلة كلية التربية الاساسية ISSN: 18157467(print) 27068536(online) Year: 2010 Volume: 14 Issue: 62 Pages: 1-8
Publisher: Al-Mustansyriah University الجامعة المستنصرية

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Abstract

The aim of the present study is to evaluate glysated hemoglobin (HbA1c) in major ,minor thalassemic patients and compare that with control,in order to investigate the possibility of using such parameters as marker in comparison with there levels in sera of normal control.

Some hematological parameters as diagnostic factors for thalessemia were estimated in sera of 50 control, 50 minor and 50 major thalassemic patients.The age for the all subjects range from (4-18) .A significant elevation in the HbF % was found in major thalessemia with value of (90.33±28.22) comparing to minor group (2.56 ± 1.12) and control group (0.44 ± 0.02).The HbA1 % for control, minor and major thalassemic patients were (7.94 ± 0.57), (11.63 ± 1.38) and (14.83 ± 1.09) respectively.
The value for HbA1c % increased also for all studied groups (5.95 ± 0.50), ( 9.04 ± 1.15 ) and (11.83 ± 0.86) for control, minor and major thalassemic patients respectively.
A conclusion could be drawn from the results of present study that the significant elevation in HbA1c in serum of major thalassemic patients compared to control was found that shown the relation between β-globin ,glucose and iron which led to oxidative strees and insulin resistance that cause endothelial damage ,therefore, the evaluation of HbA1c needs further studies

Keywords


Article
Study of Some Hematological Parameters and Determination of Glysated Hemoglobin in β-Thalassemia

Authors: Zyad Hussein Jawad AL-Qaisi --- Wasan A.K. M. --- Zaineb Moneb Al-Rubae
Journal: journal of the college of basic education مجلة كلية التربية الاساسية ISSN: 18157467(print) 27068536(online) Year: 2010 Volume: 14 Issue: 62 Pages: 165-170
Publisher: Al-Mustansyriah University الجامعة المستنصرية

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Abstract

The aim of the present study is to evaluate glysated hemoglobin (HbA1c) in major ,minor thalassemic patients and compare that with control,in order to investigate the possibility of using such parameters as marker in comparison with there levels in sera of normal control.

Some hematological parameters as diagnostic factors for thalessemia were estimated in sera of 50 control, 50 minor and 50 major thalassemic patients.The age for the all subjects range from (4-18) .A significant elevation in the HbF % was found in major thalessemia with value of (90.33±28.22) comparing to minor group (2.56 ± 1.12) and control group (0.44 ± 0.02).The HbA1 % for control, minor and major thalassemic patients were (7.94 ± 0.57), (11.63 ± 1.38) and (14.83 ± 1.09) respectively.
The value for HbA1c % increased also for all studied groups (5.95 ± 0.50), ( 9.04 ± 1.15 ) and (11.83 ± 0.86) for control, minor and major thalassemic patients respectively.
A conclusion could be drawn from the results of present study that the significant elevation in HbA1c in serum of major thalassemic patients compared to control was found that shown the relation between β-globin ,glucose and iron which led to oxidative strees and insulin resistance that cause endothelial damage ,therefore, the evaluation of HbA1c needs further studies

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