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Article
EVALUATION OF BOTOX TREATMENT FOR PATIENTS WITH PRIMARY AXILLARY HYPERHIDROSIS IN BASRAH

Author: Alaa H Al-Farhan
Journal: Basrah Journal of Surgery مجلة البصرة الجراحية ISSN: 16833589 / ONLINE 2409501X Year: 2014 Volume: 20 Issue: 1 Pages: 12-18
Publisher: Basrah University جامعة البصرة

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Abstract

EVALUATION OF BOTOX TREATMENT FOR PATIENTS WITH PRIMARY AXILLARY HYPERHIDROSIS IN BASRAH Alaa H Al-Farhan MB,ChB, FIBMS, Lecturer Plastic Surgery, Dept. of Surgery, Basrah Medical College, Basrah Iraq. Hyperhidrosis is a distressing condition that affects the social life of many patients. Botox has been discovered to treat this problem. This study aimed to evaluate the response of the patients to Botulinum toxin type A (BTX-A) and the time interval between injections during which the patient is free from symptoms. The study evaluates subjectively the response of patients with axillary hyperhidrosis to Botox with 100% scale and Hyperhidrosis Disease Severity Scale (HDSS). The time interval between injections was also evaluated. The data were collected prospectively and analyzed. This study included 21 patients with mean age of 27 years. Twenty of them were males. Of the 21 patients, 33% were subjected to multiple sessions. The response in 18 (85%) of patients was between 90-100%. The average time interval between injections was 211 days. In conclusion, botulinum toxin type A (BTX-A) has significant benefit in treating patient with axillary hyperhidrosis with rapid onset and the average duration of symptom free period was 7 months.


Article
BOTOX INJECTION FOR THE MANAGEMENT OF CHRONIC IDIOPATHIC CONSTIPATION IN CHILDREN
علاج حالات الامساك المزمن عند الاطفال باستعمال حقن البوتوكس في العضلة العاصرة الداخلية للمخرج

Authors: OSAMA ALMASHHADANI MBChB اسامة المشهداني --- MOHAMMED H. ALDABBAGH محمد الدباغ
Journal: Duhok Medical Journal مجلة دهوك الطبية ISSN: ISSN: 20717334 (online)/ ISSN: 20717326 (Print) Year: 2013 Volume: 7 Issue: 2 Pages: 16-23
Publisher: University of Dohuk جامعة دهوك

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Abstract

ABSTRACTBackground and objectives Chronic constipation stays one of the most common and challenging problems facing the doctors and the family as well. Most of these cases are idiopathic. A lot of medical and surgical treatment modalities are in use; however there is no universal way to manage resistant cases. Each method had its own benefits and side effects.Recently Botox were used in the management of idiopathic constipation in children. The aim of this study is to evaluate the role of Botox injection in the management of these cases.Methods A prospective study of 25 children with idiopathic constipation underwent Botox injection in two pediatric surgery centers. The children condition was assessed before and after the injection using the same scoring system. The material was injected in the internal sphincter.Results Patient's age ranged from 2 to 9 years. Twenty four percent of the patients had significant (p value < 0.05) and sustained improvement at three and six months after injection. While (36%) had significant improvement at three months, but they relapsed at 6 months after injection. Other 40% had no significant improvement (p value > 0.05). No patient had deterioration of his score at the time of therapy. Transient fecal incontinence was noticed in three patients and all recovered within two weeks. No complications wererecorded through out the study.Conclusions The use of Botox in managing idiopathic constipation in children is a new and safe method with good response but the problem is the significant relapse rate and should be reserved for selected resistant cases.

خلفية واهداف البحث: تعتبر حالات الإمساك المزمن عند الأطفال من المشاكل الشائعة جدا والتي قد يصعب علاجها وقد تصبح مستعصية أحيانا مما يشكل تأثيرا سلبيا على الطفل والأهل وقد ينعكس على نفسية الطفل وأهله. تستخدم عالميا أنواع كثيرة من الوسائل لعلاج هذه الحالة وقد تفشل جميعها. إن الحالات المستعصية قد تحتاج إلى تداخل جراحي ولا تخلو العمليات الجراحية من مشاكل وأضرار جانبية. يعد استعمال حقن البوتوكس طريقة جديدة قد يحل محل الجراحة ويجنب الطفل هذه المشاكل. الهدف من هذا البحث دراسة جدوى هذه الطريقة في علاج الحالات المستعصية.طرق البحث: دراسة مستقبلية شملت 25 طفلا في مركزي دهوك والموصل لجراحة الأطفال. جميع الحالات خضعت للعلاج التقليدي بالادوية الملينة لفتره لا تقل عن ثلاثة اشهر و بدون استجابة ملحوظة. درست حالتهم خلال هذه الفتره ثم تم حقنهم بمادة البوتكس وقورنت النتائج.النتائج: أظهرت الدراسة ان 24% من الاطفال تحسنوا بشكل ملحوظ ومستديم. بينما 36% بالرغم من تحسنهم في الثلاثة اشهر الاولى لكنهم عانوا من انتكاسة ورجوع الاعراض بعد ستة اشهر. 40% لم تتحسن حالتهم الصحية. لم تسجل أي اعراض جانبية من جراء العلاج.الاستنتاجات: استخدام البوتوكس في علاج الامساك المزمن عند الاطفال تعد طريقة حديثة ومأمونة.لكن لوحظ من الدراسة أن الاستجابة كانت جيدة ومستديمة لربع الحالات المدروسة فقط. أما بقية الحالات فقد كانت الاستجابة غير مرضية . لذا ينصح بتحديد استعمال هذه الطريق لبعض الحالات المستعصية.


Article
Evaluation of Electromyoghraphy Guided Botolenium Toxin Type A Injection in Treating Chronic Migraine in Babylon Province

Author: Farah Nabil Abbas
Journal: Medical Journal of Babylon مجلة بابل الطبية ISSN: 1812156X 23126760 Year: 2017 Volume: 14 Issue: 3 Pages: 442 -449
Publisher: Babylon University جامعة بابل

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Abstract

BOTOX is the first and only FDA-approved preventive treatment for chronic migraine. It's also the only treatment for people with chronic migraine. Current migraine preventive therapies are often unsatisfactory because of their limited efficacy, adverse effects, and drug interactions., Migraines typically present with pulsing head pain, nausea, photophobia (sensitivity to light) and phonophobia (sensitivity to sound). The aim of this study to evaluate the benefit of Botox injection in patients presented with chronic migraine and to determine the efficacy and safety for this kind of treatment in Babylon province. This was an interventional study of 37 subjects with a history of chronic migraine (28 female and the other 9 were male), The patients received botulinum toxin type A, 100 U into 21 intramuscular injections using a 0.5-inch-long needle EMG guided connected to the machine. and for 3 months following injection, subjects kept daily diaries in which they recorded headache frequency, duration, severity, and the occurrence of associated symptoms. The study were done during the period from January/ 2017 until July/2017. There were significant differences in patients with chronic migraine before and after treatment , in which there is significant decrease in migraine attacks per month, with reduction severity of these attacks, a significant decrease of hours in each attack and reduced incidence of migraine-associated symptoms.Pericranial injection of EMG guided BTX-A, 100U, was found to be a safe treatment that significantly reduced migraine frequency, duration, migraine severity, and reduced associated symptoms.


Article
The effectiveness of intravesical Botox in idiopathic and non-idiopathic detrusor over activity
فعالية البوتوكس في الوريد في المسبب للانسداد مجهول السبب وغير المجهول على النشاط

Authors: Bahzad Koye --- Soran Rafaat Ismail
Journal: Zanco Journal of Medical Sciences مجلة زانكو للعلوم الطبية ISSN: 19955588/19955596 Year: 2011 Volume: 15 Issue: 1 Pages: 27-34
Publisher: Hawler Medical Univeristy جامعة هولير الطبية

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Abstract

Background and objectives: We have evaluated and compared the efficacy of Botox® in the treatment of bladder over activity in Idiopathic detrusor over activity (IDO) and Neuropathic detrusor over activity (NDO) in a tertiary centre. We hypothesised that the outcome of this less invasive treatment would be more promising in patients with IDO than those with NDO.Methods: A total of 229 patients were reviewed with overactive bladder proven by urodynamic studies over the last 2 years. Of these, 174 patients received Botox® injection. 132 (75%) patients had IDO and 42 (25%) patients had NDO. 200 IU of Botox® was injected per patient in the IDO group and 300 IU in the neurogenic group.Results: Eighty one of 118 (68.7%) known patients with IDO reported being dry after receiving the Botox® compared to 20/39 (51.3%) patients with NDO. Whereas, 88/118 (68.7%) patients with IDO reported significant satisfaction compared to 25/39 (64.1%) patients with NDO.Conclusion: Botox® is an effective, minimally invasive treatment for drug refractory IDO + NDO. In comparison, patient reported satisfaction and dryness with the procedure was statistically the same. However, the IDO group responded slightly better to treatment. The average mean effect was the same in both groups.

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