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Evaluation of FSH, LH ,Testosterone , Prolactine, TSH and T4 hormones levels in different subgroups of infertile males.
تقييم FSH، LH، التستوستيرون، البرولاكتين، TSH و T4 الهرمونات المستويات في مجموعات فرعية مختلفة من الذكور بالعقم.

Author: Alaa Shaker Al-Nahi آلاء شاكر
Journal: Al-Kufa University Journal for Biology مجلة جامعة الكوفة لعلوم الحياة ISSN: 20738854 23116544 Year: 2015 Volume: 7 Issue: 3 Pages: 47-54
Publisher: University of Kufa جامعة الكوفة

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Abstract

Gonadotropins (FSH, LH) and testosterone are the prime regulators of germ cell development. Abnormal spermatogenesis is often associated with altered serum gonadotropins and testosterone. the potential relationship between other hormones, including thyroid hormones, and semen quality are still not completely understood. Thus in the present study an attempt has been made to report the degree of associations between thyroid hormones and semen quality. FSH, LH .T. PRL.T4 and TSH.hormones levels were estimated in 39 infertile men of whom 5 were azoospermia, 13 were oligozoospermic, 21 were with asthenzoospermia . Results showed statistically significant differences(P≤ 0.05) in the mean FSH, Testosteron (T.), PRL. And T4. Levels in all the infertile males studied when compared with the fertile controls (n=39). However, there is no significant difference in the mean levels of LH and TSH between the infertile and fertile men. Present study found that though men with abnormal semen profile had slightly higher in T4 concentrations in asthenozoospermia group as compared to those with normal semen profile. This study also show positive correlation between T4 and T. ( R2=0.408) and negative correlation between T4 and FSH was (R2=-0.515) ,T4 and LH was (R2=-0.345).

تعتبر هرمونات المناسل هي منظمات رئيسية للتطور النطف وهي FSH,LH,T. وكذلك مؤخرا لوحظ دور للهرمونات الدرقية ونوعية النطف .في هذه الدراسة تم قياس هرمونات FSHو LHوTو PRLوT4 في 39 من الذكور الذين يعانون من قلة الخصوبة ، وجد 5 منهم يعانون من انعدام النطف و13 يعانون منقلة النطف و21 يعانون من ضعف حركة النطف . أظهرت الدراسة وجود فروق معنوية P<0.05 في معدلات الهرمونات FSH,.T. PRL,T4 مقارنة مع مجموعة السيطرة والتي تضم 39 رجل خصب بينما لا توجد فروقات معنوية P>0.05 في كل من LH وTSH . وجد في الدراسة أيضا وجود علاقة خطية موجبة بين T4 ,و (R2=0.408) T وعلاقة خطية سالبة بين T4وFSH (R2=-0.515) وكذلك بينT4 وLH (R2=-0.345) .

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