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Article
Effect of metformin on pregnancy outcomes in women with PCOS

Authors: Asma A. Swadi اسماء عبد الجليل سوادي --- Saba M.Swadi صبا مطشر سوادي
Journal: Al-Qadisiyah Medical Journal مجلة القادسية الطبية ISSN: 18170153 Year: 2014 Volume: 10 Issue: 17 Pages: 187-195
Publisher: Al-Qadisiyah University جامعة القادسية

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Abstract

Background: Recurrent pregnancy loss (RPL) classically refers to the occurrence of three or more consecutive losses of clinically recognized pregnancies prior to the 20th week of gestation (ectopic, molar, and biochemical pregnancies are not included). we hypothesized that metformin owing to its metabolic, endocrine effect may reduce the incidence of first trimester miscarriage in PCOS women.Materials and Methods: We examined the records of all 82 nondiabetic women with the polycystic ovary syndrome who became pregnant while being seen in the out patients Clinic of the maternity teaching hospital and private clinic in AL-Qadisyiah city between January 2011 and march 2014, and who did receive metformin 3 months pre-conception (group1; n = 37) in contrast to second group who became pregnant while taking metformin and continued taking metformin at a dose of 1000–2000 mg daily throughout the first 20 weeks of gestation(group2; n = 45). Results: both groups were similar with respect to all background characteristics (age, BMI, parity, RBS, blood urea and serum creatinin).rates of early pregnancy loss in group1(82.5%) compared with (79.7%) in group2.after administration of metformin; pregnancy loss was( 83.7%,15.5%) in group1 and group2 respectively (P value = 0.001).Conclusion: administration of metformin in the first 20 weeks of pregnancy to women with PCOS was associated with a marked and significant reduction in the rate of early pregnancy loss.

أجريت هذه الدراسة على مجموعه من النساء المصابات بمتلازمة تكيس المبايض واللاتي تعرضن الى حالة فقدان حمل متكرر(اجهاض متكرر).82 امراه مصابه بمتلازمة تكيس المبايض وغير مصابات بداء السكري تم تقسيمهم الى مجموعتين (المجموعه1)وعددها 38 اعطيت عقار الميتفورمين لمدة 3 اشهر قبل الحمل وتم ايقافه عند حدوث الحمل مباشرة. اما (المجموعه2) وعددها 45 اعطيت عقار الميتفورمين لمدة 3 اشهر قبل الحمل واستمرت باخد العقار 4 اشهر بعد حدوث الحمل.النتائج:الجموعه الاولى كانت نسبة الاجهاض المتكرر فيها = 83.78% مقارنة بالمجموعه الثانيه التي استمرت باخد العقار 4 اشهر بعد حدوث الحمل حيث اصبحت نسبة الاجهاض= 15.5% . نستنتج بان استمرار استخدام عقار الميتفورمين لمدة 4 اشهر بعد الحمل يقلل من نسبة الاجهاض المتكرر وبشكل ملحوظ (p=0.001)

Keywords

PCOS --- BMI


Article
Evaluation of the Relation between Asthma, Obesity and Leptin Level in Iraqi Asthmatic Patients and the Main Risk Factors that are Associated with Leptin Level

Author: Hiba A. Hasan
Journal: Iraqi Journal of Pharmaceutical Sciences المجلة العراقية للعلوم الصيدلانية ISSN: 16833597 Year: 2011 Volume: 20 Issue: 2 Pages: 96-101
Publisher: Baghdad University جامعة بغداد

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Abstract

This study tries to clear the correlation and association between asthma, obesity and leptin levels. Also it will work to indicate the main risk factors which play role in the elevation of leptin level within asthmatic patients. This is a case control study conducted on (38) asthmatic patients and (20) healthy control who were closely similar by age, gender and BMI. The main statistical tests used were student t test, linear regression test and correlation test. Significance was set at P < 0.05. Sampling method used for this study was convenience sampling method. The main results of this study show a significant association and positive correlation between age (old age &#8805; 40 years old), female gender, BMI (overweight and obese) and steroid utilization with leptin elevation in Iraqi asthmatic patients since P values < 0.05. This study concludes that there is a correlation between obesity, age, sex and utilization of steroid with leptin level and they were the main risk factors which play role in the mechanism of elevation of leptin in Iraqi asthmatic patients.

تھدف ھذه الدراسة على إیجاد العلاقة بین الربو و السمنة و مستوى اللبتین و تحدید عوامل الخطورة الاساسیھ التي تلعب دوراًفي ارتفاع مستوى اللبتین عند المرضى المصابین بالربو . تشتمل ھذه الدراسة على ( 38 ) مریضاً مصاباً بالربو و ( 20 ) من الأشخاصاختبار الارتداد ,t الأصحاء المتقاربین بكل من العمر و الجنس و كتلھ الجسم. التحلیل الإحصائي المستخدم في ھذه الدراسة ھو اختبارتعتبر الزیادة معنویة. طریقھ جمع العینات كانت بواسطة طریقھ الاختیار المریح. كانت p< الخطي و اختبار العلاقة. إذا كانت 0,05بین العمر (اكبر من او یساوي 40 ), الإناث, كتلھ الجسم (الوزن الزائد و p< النتائج الاساسیھ لھذه الدراسة ھي علاقة معنویة 0,05البدین) و استھلاك الستیروید مع مستوى اللبتین عند المرضى العراقیین المصابین بالربو.تستنتج ھذه الدراسة بان ھناك علاقة بینالسمنة, العمر, الجنس, استھلاك الستیروید و زیادة مستوى اللبتین عند المرضى المصابین بالربو و تعتبر من عوامل الخطورةالاساسیھ التي تلعب دوراً في میكانیكیھ زیادة ھرمون اللبتین عند المرضى العراقیین المصابین بالربو.

Keywords

Leptin --- Asthma --- BMI.


Article
Obesity and Asthma Severity Among Adults Presenting to the Out Patient Clinic

Author: Hashim M. Al-Kadhimi
Journal: Iraqi Academic Scientific Journal المجلة العراقية للاختصاصات الطبية ISSN: 16088360 Year: 2012 Volume: 11 Issue: 2 Pages: 205-210
Publisher: The Iraqi Borad for Medical Specialization المجلس العراقي للاختصاصات الطبية

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Abstract

ABSTRACT:BACKGROUND:Recent studies have suggested a relationship between asthma and obesity. The risk for developing asthma increases with increasing obesity among individuals. Yet little is known about how obesity influences asthma.OBJECTIVE: To determine whether a relation of Obesity to asthma exists among adults presenting to the out patient respiratory clinic , and the correlation between Obesity and spirometric changes in patients with asthma. METHODS: A cross-sectional study was done for one hundred patients aged 17 to 70 years patients with asthma diagnosed by clinical and pulmonary function test , in the respiratory outpatient's clinic in AL Kadhmia Teaching Hospital.Collected from May to December 2010 The following parameters were assessed:Weight, height, body mass index, gender,spirometric parameters which includes of forced expiratory volume in 1 second (FEV1), forced vital capacity(FVC),FEV1FVC ratio, and forced expiratory flow50% (FEF50%)RESULTS:There were 100 asthmatic patients,32 male and 68 female. There age between 17-70 year, classified into four groups according to BMI. There was significant relation between obesity and asthma (p=0.03),this relation was statistically significant in female(p=0.003) but not in male.spirometry in male showed no statistically significant (p-value > 0.05) for FEV1, FVC FEV1FVC ratio, FEF50% in both non obese and obese, but in female statistically significant for FEV1FVC(p 0.05) ,FEF50% (p 0.036) , while no statistically significant for FEV1, FVC in both groups, for both male and female according to BMI there is statistically significant for FEF50% (p 0.015),while no statistically significant for FEV1FVC, FVC, FEV1 in both groups.CONCLUSION:There was a significant relation between asthma and obesity , in female ,but not in male. There is statistically significant difference for FEF50% ,and FEV1FVC in obese female .Also there is statistically significant difference for FEF50% in both male and female according to BMI.

Keywords

asthma --- obesity --- BMI


Article
Obesity and Overweight among Medical Teachers in College of Medicine in university of Kufa

Author: *Salam Jasim Mohammed, FIBMS. *Huda Ghazi Hamid, FIBMS.
Journal: KUFA MEDICAL JOURNAL مجلة الكوفة الطبية ISSN: 1993517X Year: 2012 Volume: 15 Issue: 1 Pages: 279-285
Publisher: University of Kufa جامعة الكوفة

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Abstract

Objective: this study was conducted to determine the prevalence of obesity and overweight and some associated factors among teachers in medical college in Kufa university.Design and methods: A cross sectional study on obesity and overweight covering 96 medical teachers in medical college in Kufa university was carried out during the period 1st of April to 1st of august 2011, data collection done by using questionnaire and measurement of weight and height by using weight display instrument which is present in community medicine departmentResults : results of this study shows that there is 36.5% of participants suffering from overweight and 18.8% suffering from obesity.In the current study no significant association between sex and body mass index (BMI) (P=0.417) and also no significant association between BMI and obesity in first degree relatives (P=0.944).This study shows no significant association between BMI and having chronic disease (P=0.856).This study shows significant association between BMI and number of meals taken between the main meals (P=0.024) also significant association between BMI and exercise (P=0.023)Conclusion: the results show that the problem is big among this group of community and the need to change their lifestyle from sedentary lifestyle to more active one and change dietary habits and establish a center for exercise inside the university and encourage all medical teachers to participate in it.

أجريت هذه الدراسة لمعرفة مدى انتشار زيادة الوزن والسمنة لمجموعة من اساتذة كلية الطب في جامعة الكوفة وبعض العوامل المساعدة على ذلك. ولهذا الغرض تم اجراء دراسة مسحية مقطعية شملت 96 استاذ في كلية الطب للفترة من الاول اربيل الى الاول من آب 2011. تم جمع المعلومات من الاساتذة من خلال استمارة تحتوي على مجموعة من الاسئلة متعلقة بالموضوع قيد البحث كذلك تمت عملية قياس الطول والوزن من خلال جهاز متخصص موجود في قسم طب المجتمع. نتائج هذه الدراسة اظهرت ان 36.5% من المشاركين يعانون من زيادة الوزن بينما 18.8% يعانون من السمنة .هذه الدراسة اظهرت انه لا توجد علاقة بين الجنس و مؤشر كتلة الجسم ( P=0.417) كذلك لا توجد علاقة بين مؤشر كتلة الجسم والسمنة لدى الاقارب من الدرجة الاولى (P=0.944) .كذلك لا توجد علاقة بين مؤشر كتلة الجسم ووجود مرض مزمن لدى الاستاذ.اظهرت هذه الدراسة انه هنالك علاقة بين الوجبات التي يتم تناولها بين الوجبات الرئيسية ومؤشر كتلة الجسم(P=0.024) كذلك هنالك علاقة بين مؤشر كتلة الجسم و التمارين الرياضية التي يمارسها الاستاذ.هذه الدراسة بينت ان حجم المشكلة كبير لدى هذه الشريحة من المجتمع والحاجة لتغيير نمط حياتهم من حياة الخمول الى حياة ذات حركة اكثر وكذلك تغيير طبيعة الغذاء .كذلك الدعوة الى بناء مركز رياضي داخل الجامعة وتشجيع الاساتذة على ممارسة الرياضة في اوقات الفراغ.

Keywords

obesity --- overweight --- BMI


Article
Gingival Health and Alveolar Bone Loss Among Iraqi Overweight Primary School - Age Pupils (Radiographic Study)

Author: Sanaa J. AL-Qasab
Journal: Tikrit Journal for Dental Sciences مجلة تكريت لعلوم طب الاسنان ISSN: 20731213 Year: 2014 Volume: 3 Issue: 1 Pages: 101-106
Publisher: Tikrit University جامعة تكريت

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Abstract

Many studies have found a strong association between obesity and various clinical and radiographical aspects of periodontal disease, most of these studies were directed toward adult age group only, while younger ages were omitted. To provide radiographic data about the effect of overweight on periodontal health status among Iraqi primary school-age pupils.The sample of this research was consist of 90 pupils of both gender (45 girls and 45 boys) with age range (6-12)years. All were examined clinically for bleeding on probing (BOP) and radiographically for alveolar bone loss (ABL). According to their percentile ranking the pupils in each gender group were divided into 3 subgroups (healthy weight, at risk of overweight and overweight). each subgroup was consist of (15 child). Greater mean values for BOP index were recorded for pupils in overweight group (0.8 for girls and 0.66 for boys) in comparison to those in healthy (0.26 for girls and 0.46 for boys) and at risk (0.4 for girls and 0.46 for boys), also greater mean values for ABL radiographically were recorded for pupils in overweight groups (1.53 mm for girls and 1.66 mm for boys) in comparison to those healthy (1.00 mm for girls and 0.8 mm for boys) and at risk (1.06 mm for girls and 1.46 mm for boys). According to paired t- test most of these differences were found to be statistically significant. On the other hand, No significant difference were recorded between different study groups on gender basis. There is a clear relation between obesity and periodontal health on both clinical and radiographical examinations.

Keywords

obesity --- bmi --- bop --- abl.


Article
Caries Experience in Relation to Weight Status among School Children Age 7-12 Year-old in Tikrit City

Author: Azhar A. Al-Kamal.
Journal: Tikrit Journal for Dental Sciences مجلة تكريت لعلوم طب الاسنان ISSN: 20731213 Year: 2016 Volume: 4 Issue: 1 Pages: 16-21
Publisher: Tikrit University جامعة تكريت

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Abstract

Caries is an infectious disease that is induced by the diet. Despite its decline in all age group on a worldwide basis, it is still a serious public health problem in children and its control should be a priority. It has demonstrated that dental caries can gradual reduce children's weight gain, which may be reversed after complete oral rehabilitation. The aim of this study was to investigate the association between age-specific body mass index (BMI-for-age) and dental caries among school children 7-12 years in Tikrit city.Material and method: A random sample of 390 school going healthy children aged 7-12 years were selected from different schools located in the Tikrit city. Height and weight for each child was recorded to obtain BMI-for- age. Dental caries was recorded (dmft, dmfs, DMFT and DMFS) according to WHO criteria. The data obtained was subjected to statistical analysis.The results showed that the underweight children were more likely to have caries experience than normal and overweight children for primary dentition (dmft 6.75 ± 0.56 and dmfs 17.21± 1.37) and for permanent dentition (DMFT 4.00 ± 0.58 and DMFS 6.48 ±1.23) with statistically no significant differences between the three groups.

Keywords

Underweight --- Overweight --- BMI --- WHO


Article
Assessment of health status among orphans in social institute in Tikrit city, Iraq.

Author: Athraa E. Ahmed
Journal: The Medical Journal of Tikrit University المجلة الطبية لجامعة تكريت ISSN: 18131638 Year: 2018 Volume: 24 Issue: 1 Pages: 128-137
Publisher: Tikrit University جامعة تكريت

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Abstract

ABSTRACT: Background: Health status among the orphans in social institute is of critical importance because they represent significant part of the community, as well as their surrounding circumstances differ from the others as all know. aim of the study to assess the health status among the orphans in social institute in Tikrit city Pateints and Methods: Across sectional study was conducted on 40 residents(boys and girls)at average age between (3-18)years by using a questionnaire form. A period between the beginning of February to the end of April of 2014.A questionnaire form was designed to the of study including information about family history , any health problem ,physical examination regarding weight ,height ,body mass index(BMI). The Results: We found that normal BMI is the commonest among them 47%. The proportion of high BMI increase with the age instead that the proportion of low BMI decrease with age. 31 % of the students between 7 –11years whereas only 39 %of those between 12-18 years were overweight. The normal BMI are equal among both females and males. Psychological problems were prominent among orphans and had become the most important contributor of lower life quality. Of 40 orphans provided credible information on the vital status of their parents; 50% had lost their father, 30% their mother and 20% had lost both parents ,About the information that was collected from them about if they have had infected with any of these communicable diseases throughout the period of staying there , we found 38% had measles, 31%had mump,18%had rubella,4%typhoid fever .Also we found high percentage (47%) of orphans had unknown history of immunization .On examination (6%)were anemic ,no jaundice, with(8%)have gross anomalies of amputated arm ,amputated arm with speech difficulty and mongolism . As well we found (17%)who were neurologically abnormal (mentally Retarded) and 26% were psychologically upset. a community-based prevention ,care approach and support from rich people should be the cornerstone of the plan for improvement . Conclusion: Orphan children had normal BMI and their age (12-18) years about 47% for each. 50% of orphan children lost their parents. Measles is a frequent infectious disease among orphan children. High percentage (47%) of orphans had unknown history of immunization.

Keywords

BMI --- Orphan --- Tikrit city


Article
Relationship of body mass index (BMI) to dyslipidemia in Type2 diabetes mellitus
علاقة مؤشر كتلة الجسم باضطراب شحوم الدم في داء السكري من النوع 2

Authors: Fadhil A. Nasser فاضل ناصر --- Abdulhussain A. Algenabi عبد الحسين الجنابي --- Ali M. Kadhim علي كاظم
Journal: Al-Kufa University Journal for Biology مجلة جامعة الكوفة لعلوم الحياة ISSN: 20738854 23116544 Year: 2019 Volume: 11 Issue: 1 Pages: 43-51
Publisher: University of Kufa جامعة الكوفة

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Abstract

T2DM is a chronic disease characterized by hyperglycemia as a result of insulin dysfunction. Both Dyslipidemia and obesity are considered cardinal features of T2DM. Aims: To study the relationship of BMI with serum lipid profile in T2DM patients.Methods: The study consisted of 200 T2DM patients and 200 control individuals. Phenotypic parameters included are body mass index (BMI), and fasting blood sugar (FBS) and lipid profile.Results :The statistical analyses used to analyze the data.A significant positive correlation of serum TC, TG and LDL levels and significantly negative correlation of serum HDL levels with BMI in patients with T2DM (p<0.001).

T2DM هو مرض مزمن يتميز بارتفاع السكر في الدم نتيجة لضعف الأنسولين. يعتبر كل من دسليبيدميا والسمنة من السمات الأساسية ل T2DM.الأهداف: لدراسة العلاقة بين مؤشر كتلة الجسم وملف الدهون في الدم لدى مرضى T2DM.الطريقة: تكونت الدراسة من 200 مريض T2DM و 200 من أفراد التحكم. المعلمات المظهرية المدرجة هي مؤشر كتلة الجسم (BMI) ، وصيام نسبة السكر في الدم (FBS) والدهون الشخصي.النتائج: التحليلات الإحصائية المستخدمة لتحليل البيانات.علاقة إيجابية كبيرة من مستويات TC المصل ، TG و LDL وارتباط سلبي كبير من مستويات HDL في الدم مع مؤشر كتلة الجسم في المرضى الذين يعانون من T2DM (P <0.001).

Keywords

T2DM --- BMI --- lipid profile --- T2DM --- BMI --- lipid profile


Article
Association between Interleukin-5 & Body Mass Index among Iraqi Asthmatic Patients

Authors: Wala'a E. Jasim --- Batool A. Al-Haidary --- Yacoob Y. Al-Rubayei
Journal: Journal of the Faculty of Medicine مجلة كلية الطب ISSN: PISSN: 00419419 / EISSN: 24108057 Year: 2007 Volume: 49 Issue: 1 Pages: 116-120
Publisher: Baghdad University جامعة بغداد

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Abstract

Background: Asthma is an allergic hypersensitivity disease in which many mediators play a role in its pathogenecity. One of these etiological agents is the mediators such as Interleukin-5 (IL-5). The aim of this study to demonstrate the association between IL-5 and obesity in asthma development. Materials & Methods: One hundred and four sera samples for asthma cases have been studied in comparison with 41 non-asthmatic bronchitis as a patient controls beside 30 apparently healthy controls. Cytokine has been estimated using ELISA method in correlation with Body Mass Index (BMI). Results: This study revealed a significant correlation between IL-5 concentration and BMI (P<0.05), particularly among females. Conclusion: There is certain correlation between obesity and asthma accompanied by IL-5. Key

Keywords

Asthma --- IL-5 --- ELISA --- BMI.


Article
Effect of leptin level in non insulin dependant (type 2) obese diabetic subjects

Authors: Othman G. Othman --- Maysaa J. Majeed
Journal: Journal of the Faculty of Medicine مجلة كلية الطب ISSN: PISSN: 00419419 / EISSN: 24108057 Year: 2009 Volume: 51 Issue: 1 Pages: 76-80
Publisher: Baghdad University جامعة بغداد

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Abstract

Background: Determine how do obesity and type2 diabetes intertwined? and what it takes to turn an obese person into a person with diabetes. That link may help to understand why some obese people never develop diabetes while many others do.Serum sugar level was used as indicator of insulin level; leptin level was used as indicator of leptin resistance.A total of 50 obese subjects were involved in this study, 25 obese subject (BMI >30) had diabetes mellitus type 2(no insulin dependant), selected from Baghdad teaching Hospital in Baghdad /Iraq. The remaining 25 obese (BMI >30) were normal healthy individuals.Patients and Methods: ELSA technique was used for the measurement of serum leptin. Blood sugar was determined by using colorimetric method. Data were expressed as mean ± SD results and were evaluated using the student t-test for paired data. Conventional methods were used for the correlation and regression analyses.Results: Obtained results showed that the level of serum leptin in healthy obese subjects were significantly lower than that of obese diabetes subjects. , serum sugar in non diabetic obese subjects was significantly lower than obese diabetes type2 subjects.Serum leptin correlated negatively with level of serum sugar at the same time had a positive correlation with BMI in non diabetic obese group whereas level of serum leptin correlated positively with each of BMI and serum sugar in diabetic type2 group. All results are thoroughly discussed in the text.Conclusion: The present study indicates the possibility of future development of a new class of anti diabetic agents that act centrally and independent of insulin action.

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