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Article
Complications of Bone Marrow Aspiration and Biopsy: a New Unexpected Ris

Author: Najlaa Badr Alawadi
Journal: Iraqi Academic Scientific Journal المجلة العراقية للاختصاصات الطبية ISSN: 16088360 Year: 2013 Volume: 12 Issue: supplement Pages: 712-715
Publisher: The Iraqi Borad for Medical Specialization المجلس العراقي للاختصاصات الطبية

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Abstract

ABSTRACT:BACKGROUND:Bone marrow examination represents an essential tool for diagnosis and monitoring of haematological and non-haematological disorders. Although some hazards are recognized, bone marrow aspiration and trephine biopsy are generally thought to be safe procedures. OBJECTIVE:The aim of this study is to identify the possible complications associated with the bone marrow aspiration and biopsy procedures.METHODS: In this study, 2156 cases of bone marrow aspiration with or without trephine biopsy were done in Merjan Teaching Hospital, Babil governorate, Iraq during a five year period from 1st Feb 2006 to 1st Feb 2011. These procedures were done under local anesthesia. The complications associated with these procedures were reported.RESULTS: A new previously unreported complication was seen in 2 patients as they developed sudden apnea and loss of consciousness.The final diagnosis in both patients was acute lymphoblastic leukemia with huge mediastinal widening and they were lying in prone position during the procedure.Bleeding was seen in 2/2156 (0.09%) cases. Prolonged pain was documented in one case. No infection was reported.CONCLUSION: Bone marrow examination is generally safe, however apnea and loss of consciousness can occur in patients with a huge mediastinal mass compressing trachea and/or major chest vessels when the procedure is done in prone position.KEY WORDS: Bone marrow aspiration.


Article
Evaluation the Role of Bone Marrow Examination in Diagnosis of Hematological Diseases in Hemato-Oncology Centers in Kurdistan Region

Authors: Shorsh Jameel Ridha --- Shorsh Jameel Ridha --- Hoger Ismael Muhammed Sarhang
Journal: Iraq Joural of Hematology المجلة العراقية لامراض الدم ISSN: 20728069/25432702 Year: 2016 Volume: 5 Issue: 1 Pages: 98-113
Publisher: Al-Mustansyriah University الجامعة المستنصرية

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Abstract

Background: Bone marrow aspiration and trephine biopsy have an important role in evaluationand diagnosis of most hematological and some non hematological disorders.Objectives: The aims of this study were to assess the value of bone marrow examination indiagnosis of hematological diseases and determination of frequency and causes of dry tapmarrow.Patients and Methods: This study was prospective only and it was conducted from January 2013to June 2013 at Hiwa and Nanakaly hospitals in Sulaymaniyah and Erbil respectively. A totalnumber of 245 cases were underwent bone marrow examination. Touch imprint was prepared in astate of dry tap marrow. Sudan black stain was used in acute leukemia.Results: The patients comprised 138 (56.3%) males and 107 (43.7%) females, with ages rangingfrom 1 to 81 years and the mean age of cases was 36.7± 24 years. The most frequent clinicalfinding of patients underwent bone marrow examination were pallor (71.4%), followed by fever(32.2%). The main indications were present of blast cells in peripheral circulation 69 (28.2%),followed by bone marrow assessment for staging of lymphoma 37 (15.1 %). The most commondiagnoses encountered were: Acute leukemia 69 (28.2%), Active marrow (negative forlymphoma) 27 (11.1%) and active marrow 24 (9.8%). The frequency of dry tap was (4.08%) andthe most common causes were: acute leukemia and faulty technique (normal marrow).Conclusion: Bone marrow examination is an important diagnostic tool in the diagnosis andstaging of various hematological disorders.Keywords: Bone Marrow Aspiration, Trephine Biopsy, Hematology, Kurdistan


Article
Monitoring of patients undergoing examination of bone marrow aspiration and biopsy
مراقبة المرضى الذين تحملوا فحص سحب واخذ خزعة من نخاع العظم

Author: Hakemia Shaker Hasian حكيمه شاكر
Journal: IRAQI JOURNALOF COMMUNITY MEDICINE المجلة العراقية لطب المجتمع ISSN: 16845382 Year: 2007 Volume: 20 Issue: 4 Pages: 102-106
Publisher: Al-Mustansyriah University الجامعة المستنصرية

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Abstract

Abstract:Background: Monitoring of the patient is to improve the outcome of the bone marrow aspiration and biopsy procedure by decreasing the risk of the procedure itself Objective: 1-To monitor the heart rate , and blood pressure of the patient before ,during ,and until 6 minutes after the needle of bone marrow biopsy and aspiration has been with drawn,2- Early detection of any signs and symptoms of distress 3-to monitor the ECG abnormalities that might occur during the bone marrow aspiration and biopsyMethods: The study consisted of 33 patients referred consecutively to the Baghdad teaching hospital 7th floor ( bone marrow aspiration and biopsy clinic) Before bone marrow aspiration and biopsy , baseline 12 leads ECG ,blood pressure, and heart rate were recorded .Lead II ECG, heart rate ,blood pressure were continuously recorded during the procedure until 6 minutes after the needle had been with drawn and 12 lead ECG ,blood pressure and heart rate gain recorded at the time .Results: Heart rate , systolic, diastolic blood pressure before the procedure were significantly increase in comparison with during period of the bone marrow aspiration and biopsy and decreases in number of patients suffering from nausea, vomiting ,pallor, chest pain, dyspnea, general pain when comparing to non suffering from signs and symptomsConclusion: Electrocardiographic changes are rarely found in patients undergoing bone marrow aspiration. According to the results the investigatore recommended to preparing and training of bone marrow aspiration and biopsy clinic staff for patient care before, during and after bone marrow aspiration and biopsy

الملخص:خلفية الدراسة:-مراقبة المريض بحسين من أجراء سحب واحذ خزعة من نخاع العظم وذلك بتقليل نتائج خطورة الأجراءالهدف: 1- مراقبة ضربات القلب وضغط الدم للمرض قبل وخلال و لفترة زمنية لمدة 6 دقائق بعد سحب الإبرة. 2- الكشف المبكر عن أي علامة وعرض من علامات الإجهاد. 3- مراقبة الحالات الشاذة في تخطيط القلب الكهربائي خلال اجراء سحب واخذ خزعة من نخاع العظم.الطريقة :شملت الدراسة على (33)مريضا أحيلوا بصورة متعاقبة إلى مستشفى بغداد التعليمي / الطابق السابع (عيادة مرضى سحب واخذ خزعة من نخاع العظم ) . قبل أجراء سحب واخذ خزعة من نخاع العظم الخطوات الرئيسية تم تسجيل 12 قطب من تخطيط آلقلب الكهربائي وضغط الدم وسرعة ضربات القلب وباستمرار تم تسجيل سرعة ضربات القلب من القطب الثاني لتخطيط القلب الكهربائي مع ضغط الدم خلال أجراء سحب واخذ خزعة من نخاع العظم ولمدة 6 دقائق بعد أجراء سحب واخذ خزعة من نخاع العظم.حيث سجل مرة ثانية 12 قطب من تخطيط القلب الكهربائي ,وضغط الدم وسرعة ضربات القلب في ذلك الوقت.النتائج :هنالك زيادة ذات دلالة معنوية في سرعة نبضات القلب. و ضغط الدم العالي مقارنة بفترة قبل وخلال أجراء سحب واخذ خزعة من نخاع العظم وقلة في عدد المرضى الذين عانوا من غثيان وتقيء وشحوب لون الجلد والآلام في الصدر مع ضيق في التنفس وألم عام وشامل مقارنة بأولئك الذين لم يعانوا من العلامات والأعراض المرضية . النصائح: التغير في تخطيط القلب نادر حدوثه مع المرضى الذين يخضعون لأجراء سحب واخذ خزعة من نخاع العظم . وطبقا لهذه النتائج توصى الباحثة بتهيئة وتدريب الملاكات العاملة بوحدة عيادة مرضى سحب واخذ خزعة من نخاع العظم حول العناية التمريضية قبل ,خلال وبعد سحب واخذ خزعة من نخاع العظم


Article
A review of bone marrow examinations in Ibn Sena Teaching Hospital in Mosul
مراجعة فحوصات نخاع العظم في مستشفى ابن سينا التعليمي في الموصل

Author: Mohammed H. Awaad حمد حسن عواد
Journal: Annals of the College of Medicine Mosul مجلة طب الموصل ISSN: 00271446 23096217 Year: 2018 Volume: 40 Issue: 2 Pages: 69-73
Publisher: Mosul University جامعة الموصل

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Abstract

Objective: To assess the indications and different pathologies of bone marrow aspirates and to evaluate and analyze a considerable percentage of dry blood taps and normal bone marrow aspirates.Methods: A retrospective study. All request procedures and reports of bone marrow examinations between January 2001 and December 2008 were reviewed.Results: There were (2008) bone marrow aspirations performed during the period, 1258 (63%) of the marrow aspirations were non-malignant and 750 (37%) of the samples were found to be malignant. In 216 cases (11%) marrow aspirates were found to be non-conclusive. There were 154 (8%) full blood tap a recent full blood picture performed at the time of the bone marrow examination. The commonest indication was for investigation of thrombocytopenia and the most frequent diagnosis encountered was acute leukemia. Conclusion: The bone marrow aspiration and trephine biopsy (scientific speaking) are complementary and give a higher diagnostic yield when both are available for a patient. This study also reveals that the failure rate of obtaining either of the samples is not significant and this issue needs to be addressed appropriately.

الهدف: أجريت هذه الدراسة لتقييم كفاءة فحص نخاع العظم ودواعي أجرائه وانسجام نتائج الفحص مع التشخيص النهائي المتوقع ومنع اجراء الفحص غبر الضروري والأخطاء.طريقة البحث: تم مراجعة طلبات وتقارير نتائج الفحوصات للفترة من كانون ثاني 2001 الى كانون أول 2008 للذين أجري لهم الفحص بلغ عددهم 2008 فحص نخاع العظم في مختبر مستشفى ابن سينا التعليمي في الموصل.النتائج: وأظهرت نتائج الدراسة أن 1258 (63%) من الحالات هي حالات مرضية غير خبيثة. وأن 750 (37%) حالة فقط هي خبيثة وأن 216 حالة (11%) حالة كانت عملية رشف نخاع العظم غير مجدية. إن أكثر الحالات تستدعي إجراء الفحص هي نقص الصفائح الدموية وأكثر الحالات المشخصة هي سرطان الدم الحاد اللوكيميا.الاستنتاج: نستنج بأن فحص نخاع العظم بنوعية (خزعة النخاع ورشف النخاع) أحدهما مكمل للآخر ويعطي تشخيص أعلى دقة. بينت هذه الدراسة أن فشل الحصول على أي من النموذجين ليس ذو معنى وهذا يحتاج الى متابعة مناسبة.

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