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Article
The possible association between Chlamydia pneumoniae infection and asthma.

Authors: Haider Ahmed Shemran --- Haider S. Kadhim --- Mahmood Sh. Al-Zaidi
Journal: Journal of the Faculty of Medicine مجلة كلية الطب ISSN: 00419419 / 24108057 Year: 2010 Volume: 52 Issue: 3 Pages: 316-317
Publisher: Baghdad University جامعة بغداد

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Abstract


Background: Many etiological factors have been implicated in the pathogenesis of Asthma like; viruses, bacteria and Chlamydia pneumoniae. This study focuses on the role of Chlamydia pneumoniae in asthma pathogenesis.Patients and Methods: The detection of Anti-Chlamydia pneumoniae antibodies IgA, IgM and IgG in patients by ELISA, for 35 patients, 18 asthmatic patients, 12 patients with chest infection with no history of asthma, and 5 apparently healthy as control subjects.
Results: The results showed that 80% and 70% of the patients were negative for anti- Chlamydia pneumonia antibodies IgA and IgM respectively, while significantly (p<0.05) high number (73%) of patients were positive for IgG, of which significant number (p<0.05) of them, 63% were asthmatic and 36% were non-asthmatic chest infection.
Conclusion: this study may support the association between Chlamydia pneumoniae and asthma.


Article
Immunoflorescent Study of Placenta-Bound IgG in Women with Common Infection at Term

Author: Wifaq Mahmoud Ali AL-Wattar
Journal: Iraqi Academic Scientific Journal المجلة العراقية للاختصاصات الطبية ISSN: 16088360 Year: 2008 Volume: 7 Issue: 3 Pages: 264-267
Publisher: The Iraqi Borad for Medical Specialization المجلس العراقي للاختصاصات الطبية

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Abstract

ABSTRACT:BACKROUND:The level of IgG increases during pregnancy reaching a maximal level at term and was clamed to have a role in the immunological initiation of labor at term, some times the presence of infection during pregnancy might increases the level of such antibody as part of the maternal humeral immune response toward invading pathogens, among which U.T.I and chest infection.OBJETIVE:The evaluation of the role of placenta- bound IgG as a part of immune response against the infectious agents causing UTI and or chest infection during the second half of pregnancy.METHODS:Fifty one women were included in this study delivered normally at Baghdad teaching hospital,17 women had UTI and 18 where complaining of chest infection at time of sample collection compared with 17 women delivered normally and apparently healthy as a control group ,the level of IgG was detected by direct immunoflorescent test (IF).RESULTS:The study showed a significant higher level of IgG in the placental biopsy of women with UTI, and chest infection than those of the control group.CONCLUSION:The level of placenta –bound IgG is higher in women having infectious disease during pregnancy than those with normal uncomplicated gestation, which could be considered as a reflection for the level of passive immunity donated to the baby during his first six months of life.

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