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Article
THE USE OF TADALAFILIN PATIENTS WITH CHRONIC PROSTATITIS/CHRONIC PELVIC PAIN SYNDROME

Author: Hassanain F Hasan حسنين فرحان حسن
Journal: IRAQI JOURNAL OF MEDICAL SCIENCES المجلة العراقية للعلوم الطبية ISSN: P16816579,E22244719 Year: 2013 Volume: 11 Issue: 1 Pages: 78-83
Publisher: Al-Nahrain University جامعة النهرين

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Abstract

Background:The treatment of chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) can be a frustrating challenge to physicians and many drugs had been used with variable results.Objective:To evaluate the safety and the efficacy of adding 5 mg tadalafil for patients with CP/CPPS with the conventional treatment.Methods:Thirty five patients received tamsulosin 0.4 mg capsule once daily, levofloxacin 500mg tablet once daily and indomethacin rectal suppository 100 mg once daily served as control group. Another 35 patients received the alpha blocker, levofloxacin and NSAID as above with tadalafil 5 mg once daily for 1 month period comprised tadalafil group. The NIH Chronic Prostatitis Symptom Index (NIH-CPSI) assessment was completed by each patient at baseline and 4 weeks after the drug therapy to assess the response to treatment. We consider in our study the chronic prostatitis/CPPS or category IIIa or b according to NIH classification system.Results:No significant difference in mean age and baseline score in between groups was found. After one month of starting treatment, it had been found that NIH-CPSI/pain, urinary and quality of life domains were significantly changed from (12.8±1.44, 5.9±1.77 and 8.8±1.82) at baseline to (9.6±1.04, 3.55±0.99 and 3.88±1.31) respectively in group A. In group B also there was a significant reduction in the NIH-CPSI among patients in this group; the baseline NIH-CPSI/pain, urinary and quality of life domains were (13.4±1.66, 5.8±1.85 and 9.3±1.92) and changed to (6.28±0.90, 2.65±0.86 and 2.69±1.43) respectively after treatment. The total NIH-CPSI was 27.5±4.78 and changed to 17.03±3.91 after treatmentin group A and 28.5±4.49 changed to11.62±3.59 in group B. Conclusion:The use of tadalafil in patients of CP/CPPS with conventional treatment for 1 month was safe and has high efficacy in reducing the symptoms for the patients and improving the quality of life.Keywords:Tadalafil, chronic prostatitis, chronic pelvic pain syndrome


Article
Culture of Bone Sinus Track

Author: Ali Hafid Khudair
Journal: Al-Kindy College Medical Journal مجلة كلية الطب الكندي ISSN: 18109543 Year: 2006 Volume: 3 Issue: 1 Pages: 35-39
Publisher: Baghdad University جامعة بغداد

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Abstract

Background: Sinus track represents the site of
drainage of chronic osteomyelitis, and is caused by
improper treatment of acute hematogenous
osteomyelitis ended with sequestrum formation,
trauma results in compound fracture, post operative
complications of the bone operation, and / or
tuberculous osteomyelitis. Sinus track culture of
chronic osteomyelitis is a very important & difficult
subject to deal with, because collection and
cultivation of material need patience and skillful to
reach best results
Mthods: Culture comparison of sinus track and
operative specimens was performed on 20 patients
with chronic osteomyelitis. This was conducted to
isolate the causative microorganisms of the chronic
sinuses discharge.
The investigation included a prospective study
during the period from October 1999- August 2000
in Tikrit Teaching Hospital.
The aim of the study was to culture compare
between the reliability of sinus track with bone
specimen obtained by operative method to know
actual causative agent of chronic bone infection.
Results: Eighteen patients (90%) had a single
isolated pathogen from their operative and sinus
specimens, while 2 (10%) patients have more than
one organism.
Sinus track cultures show the specificity of 100%
and predictive value of 91.6%, while sensitivity
shows 94.5%, was more dependent in the study.
Sinus track cultures were proved to be unreliable
source for the isolation of Staph. epidermidis while
it is proved to be a reliable source for isolation of
other type of bacteria caused chronic osteomyelitis.
Isolation of Staph. aureus from sinus track correlated
with the presence of Staph. aureus in the operative
specimen.
Conclusion: Syringe aspiration of material is
proved to be more reliable than cotton swab.
A cotton swab can miss most of the causative
organisms especially the anaerobes and specific
bacteria as Mycobacterium tuberculosis, or it may
contain some contaminants. Mycobacterial isolation
was limited to only 2 patients in the present study.
Keywords:Chronic,osteomyelitis, sinus

Keywords

Chronic --- osteomyelitis --- sinus


Article
Chronic Renal Failure in Children Admitted to Children Welfare Teaching Hospital

Author: Nariman Fahmi Ahmed
Journal: Iraqi Academic Scientific Journal المجلة العراقية للاختصاصات الطبية ISSN: 16088360 Year: 2008 Volume: 7 Issue: 1 Pages: 12-17
Publisher: The Iraqi Borad for Medical Specialization المجلس العراقي للاختصاصات الطبية

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Abstract

ABSTRACT:BACKGROUND:Chroic renal failure (CRF) is a devastating medical, psychological, social and economic problem forpatients and their families.AIM OF THE STUDY:The aim of the present study was to determine the etiology, clinical presentations and highlighttreatment modalities used for patients with CRF admitted to children welfare teaching hospital.PATIENTS' AND METHODS:A Retrospective study of all children with CRF admitted to children welfare teaching hospital duringthe period from 1stof jan.2002 to 1st of jan.2007 were included in the study .CRF was defined ashaving glomerular filtration rate less than 80m1 /min/1.73m2.RESULTS:The study group included 50 patients with CRF below 17 years of age,29(58%) males and 21(42%)females. Male: female ratio 1.38:1Their age ranged between (1m -17 year).Twenty (40%) patients were above 10 years of age. In thisstudy the mean glomerularFiltration rate was (29.5 + 18.5m1 /min/1.73m2).Congenital abnormalities were the major cause of CRF, it was found in 18 patients (36%), followedby hereditary conditions in 14 (28%) patients and glomerular diseases in 13 (26%) patients.The most common presenting symptom was anemia. It was found in 16(32%) patients followed byhypertension in 12 patients (24%) and failure to thrive in 12(24%) patients.Twenty-one patients (42%) received peritoneal dialysis, four (8%) received hemodialysis. Renaltransplant was done to 3 patients (6%).CONCLUSION:Congenital abnormalities was to the most common cause of CRF in our patients. Establishing registrysystem that provide detailed information concerning the incidence, causes, and overall outcomes ofmild to severe renal functional impairment acquired during developmental age can clarify further thenatural history of the disease and the factors that influence its course.


Article
SERUM LEVELS OF 2MICROGLOBULIN AND SOME BIOCHEMICAL PARAMETERS AMONG CHRONIC HEPATITIS B PATIENTS

Author: Maysoon K. Al-Shaikle
Journal: Al-Nahrain Journal of Science مجلة النهرين للعلوم ISSN: (print)26635453,(online)26635461 Year: 2010 Volume: 13 Issue: 4 Pages: 39-44
Publisher: Al-Nahrain University جامعة النهرين

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Abstract

The aim of this study was to estimate the level of 2microglobulin (B2M), total serum bilirubin(TSB) and alanine aminotransferase (ALT) in the sera of (30) chronic hepatitis B (CHB) patients(patients group) and (30) healthy HBV carriers as (control group). The study showed that levels of2 microglobulin were high among patients group (3.41 1 mg/L), while it was normal amongcontrol group (1.42 0.35 mg/L). Regarding biochemical parameters, it was found that (TSB) and(ALT) were increased among patients group, and their level were (37.66 30.8 mol/L) and(43.6 32.51 U/L) respectively. While it was normal among control group (4 0 mol/L) and(17.4 7.16 U/L) respectively.


Article
Efficacy of Azithromycin in Comparison with Metronidazole in the Treatment of Chronic Periodontitis

Author: Jawna’a K Mammdoh
Journal: Al-Rafidain Dental Journal مجلة الرافدين لطب الأسنان ISSN: 18121217 Year: 2011 Volume: 11 Issue: 18 Pages: 323-330
Publisher: Mosul University جامعة الموصل

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Abstract

Aims: The aim of this study was to evaluate the clinical effects of systemic azithromycin as an adjunct to scaling and root planning (SRP) and compared it with metronidazole in the treatment of chronic per-iodontitis. Materials and Methods: Forty four patients with clinical diagnosis of chronic periodontitis underwent scaling and root planing were divided into three groups. The first group (n = 20) patients received azithromycin 500 mg once daily for 3 days plus SRP. The second group (n= 11) received met-ronidazole 500 mg 3 times daily for 7 days plus SRP. The third control group (n= 13) patient received SRP plus placebo treatment once daily for 3 days. Clinical measurement including gingival index, bleeding on probing and probing pocket depth were performed at the base line visit and 40 days after taking the treatment. Results: The results obtained at 40 days from the base line showed better signifi-cant improvement in all clinical parameters (p≤ 0.05) in the treated groups, except for bleeding on probing in control group were no significant improvement was reported. Azithromycin plus SRP give the greatest improvement in mean gingival index and bleeding on probing (p< 0.05) when compared with the control group but no significant differences were observed between metronidazole treated group and the control group. Conclusions: The adjunctive use of azithromycin with SRP has potential to improve periodontal health over SRP only and could be an interesting alternative to metronidazole from patients with chronic periodontitis


Article
The Value of Using Echocardiography in Patients of Advanced Liver Disease with Cardio Pulmonary Complications

Authors: Basil. N. Saeed --- Sameer Hakeam --- Lutf Ahmed --- Jalal Ahmed
Journal: Iraqi Academic Scientific Journal المجلة العراقية للاختصاصات الطبية ISSN: 16088360 Year: 2009 Volume: 8 Issue: 4 Pages: 323-326
Publisher: The Iraqi Borad for Medical Specialization المجلس العراقي للاختصاصات الطبية

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Abstract

ABSTRACT:BACKGROUND:Patients with chronic liver disease are liable to get cardio – pulmonary complications, one of these complications is development of pulmonary hypertension ranging from mild to it's sever form – this complication could give some abnormal findings in chest x-ray, electrocardiography but more prominently by echocardiography.OBJECTIVES:To clarify the benefit of using the echocardiogram is detecting pulmonary hypertension prior to the use of invasive methods (catheterization) in patients with advanced liver disease.METHODS:A total of 50 patients with chronic liver diseases (cirrhosis, chronic active hepatitis) their age range is (25-70 years) (mean are 37.07 years), the fifty patients were free from any cardiac or respiratory diseases.The study extending from December 2007-August 2008. All patients went through full history and routine blood test: including complete blood picture, fasting blood sugar, blood urea & screatinne, lipid profile, liver function tests, clinical examination, and investigations included routine blood test, chest x-ray, and electrocardiography, echocardiography (Transthoracie and transoesphageal). The child-Pugh score used for assessing the severity and prognosis of chronic liver disease and it classified into three groups (A, B, C) used in this study.RESULTS:Fifteen patients from the 50 cases (30%) only proved to have cardio-pulmonary changes (i.e. pulmonary hypertension right ventricular hypertrophy and dilatation with the mean value of ≥ 25mm Hg at rest or ≥ 30mm Hg during exertion) those patients were having fatigue in (70%) of them while dysponea, chest pain, cyanosis, syncope were detected in 30%, 10%, 1%, 2% respectively in those cases of pulmonary hypertension with chronic liver disease.CONCLUSION:The use of non invasive methods especially echocardiography were helpful in detecting the presence of pulmonary hypertension in patients with chronic liver disease


Article
TOXOLOGICAL AND PATHOLOGICAL STUDY OF DIAZINON ON MALE WILD PIGEON ( Culumba livia gaddi) IN BASRAH CITY
دراسة أمراضية سميه للديازينون في ذكور الحمام البري في مدينة البصرة

Author: Majeed S. K., صالح كاظم مجيدٍ
Journal: Basrah Journal of Veterinary Research. مجلة البصرة للابحاث البيطرية ISSN: Print:18138497 E; 24108456 Year: 2012 Volume: 11 Issue: 1 Pages: 270-282
Publisher: Basrah University جامعة البصرة

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Abstract

A five months as toxologic pathologic study of diazinon on male wild pigeons ( Culumba livia gaddi) by oral intubation was done. The animals divided to four groups each with six pigeons: A( high dose 0.6 mg), B( intermediate dose of 0.3 mg), C( low dose 0.15 mg) and D(untreated control). Clinical observation of treated pigeons did not show significant changes, but a clear histopathological changes were founded. In livers of group A showed a periportal foci of mononuclear cells, while, another showed a septal fibrosis and foci of mononuclear cells in the same group. A foci of mononuclear cells were shown in group B. In group C there was a periportal fibrosis, congestion and foci of mononuclear cells. A dilated cortical tubules were showed in kidney in all groups. While, in section from sciatic nerve related to groups (A-C) showed degenerated and vacuolated nerve fibers, and vacuolated nerve fibers were founded in group B and C. A several degenerate vacuolated nerve fibers were founded in the spinal cord of pigeons in A group, while, in B group a degenerate, vacuolated nerve fibers. In C group a several degenerate, vacuolated nerve fibers

Keywords

Sub chronic --- diazinon --- vaculation


Article
Follow Up of Sixty Patients with Chronic Lymphocytic Leukaemia

Authors: Alaadin Sahham Naj --- Bassam Francis Metti --- Fouad M. AL-Kasab*
Journal: Iraqi Academic Scientific Journal المجلة العراقية للاختصاصات الطبية ISSN: 16088360 Year: 2013 Volume: 12 Issue: 2 Pages: 223-229
Publisher: The Iraqi Borad for Medical Specialization المجلس العراقي للاختصاصات الطبية

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ABSTRACT: BACKGROUND: Chronic lymphocytic leukemia(CLL) is heterogeneous in its clinical course and typicallydiagnosed when patients presented with symptoms of lymphadenopathy, cytopenia ,constitutionalsymptoms or infection. Now 50% of patients with CLL are likely to be diagnosed when an elevatedlymphocyte count is discovered incidentally .OBJECTIVE: Description of various presentation in adult patients with CLL, complications that happenedduring the course of their disease, cause of death and overall survival in these patients.PATIENTS AND METHODS: Sixty Iraqi adult patients with CLL were studied retrospectively and prospectively. These patientswere assessed clinically and stratified with Rai staging, with follow up for any complications thatoccurred during their course of disease from time of diagnoses till last visit or death. RESULTS: In this study, the age group more than fifty years form 50(83.3%) patients and those less than fiftyform 10(16.6%) patients. The commonest clinical feature reported was constitutional symptoms in19(31.6%)patient. Rai staging of these patients found to be that most of patients intermediate stageII 22(36%) and advanced stage III, IV in 34(56.6%) Regular follow up of these patients revealed that autoimmune disorder occur in 6(10%) patients, inform of autoimmune hemolytic anemia (AIHA),pure red cell aplasia (PRCA)and immunethrmbocytopenia (ITP).The increase susceptibility to infection by different viral , bacterial andparasitic infection was noticed in these patients during their course of illness. Death in thesepatients was due to infection with HBV and liver failure in 2(3%)patients, obstructive jaundice andhepatic encephalopathy in one(1.6%)patients, sepsis in 4(6.6%), bleeding in one (2.04%) ,renalfailure in two patients (1.6%),chronic sinusitis with fungal infection and renal failure in one (1.6%)patient ,Richeters transformation and disease progression in 7(11.6%) or due to co morbidillness (stroke, ischemic heart disease, heart failure ) in 3(5%) patients. The overall survival forthese patients within five years was 50% .CONCLUSION :Constitutional symptoms was the commonest presentation of CLL Iraqi patients. The indolentcourse of the disease in CLL patients, still can be interrupted by different complications includinginfection, autoimmune disorder, and malignancy.


Article
p53 expression in chronic lymphocytic leukaemia

Authors: Nasir AL-Allawi --- ferial hilmi --- khudair A- Kalisi خضير عباس الخالصي --- sura maher --- et al.
Journal: Journal of the Faculty of Medicine مجلة كلية الطب ISSN: 00419419 Year: 2005 Volume: 47 Issue: 2 Pages: 126-131
Publisher: Baghdad University جامعة بغداد

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Article

Author: Muataz Fawzi Hussein
Journal: Iraqi Academic Scientific Journal المجلة العراقية للاختصاصات الطبية ISSN: 16088360 Year: 2013 Issue: supplement Pages: 659-667
Publisher: The Iraqi Borad for Medical Specialization المجلس العراقي للاختصاصات الطبية

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ABSTRACT: BACKGROUND: Percutaneous coronary intervention for chronic total occlusion lesions is technically difficult despite equipment advances. Changes in electrocardiographic patterns such as Q wave during total occlusion can provide information about procedural success and myocardial viability. OBJECTIVE: The aims of study are to investigate clinical, electrocardiographic and procedural characteristics of chronic total occlusion and the relation of these variables to the procedural success rate.PATIENTS AND METHODS:In this study, clinical, electrocardiographic and coronary angiographic data of (100) patients with chronic total occlusion lesions who underwent percutanous coronary intervention between May 2010 and March 2011 at the Iraqi center for heart diseases were analyzed. The clinical data were collected using the patients’ files and angiographic data by the observation of their films. Chronic total occlusion was diagnosed from clinical events including myocardial infarction or worsening of their symptoms or previous angiography.RESULTS: There were 100 patients with chronic total occlusion. Successful recanalization with stent deployment was accomplished in 65 patients (65%), while unsuccessful recanalization was found in 35 patients (35%). No major cardiovascular events occurred among both groups. The success rate of PCI was significantly more in lesions shorter than 15 mm, presence of tapered stump, angulations less than 45 degree, duration less than 3 months and TIMI 1 flow grade (p values were significant). Presence of Q wave was associated with severe angina , decreased left ventricular ejection fraction, critical lesions other than chronic total occlusion, T wave inversion and more regional wall motion abnormalities ( p values were significant). The most common cause of procedural failure was inability of guide wire to cross through the totally occluded segment.CONCLUSION: Percutaneous coronary intervention is a safe and useful procedure for revascularization of coronary chronic total occlusion lesion. The procedural success rate was related to certain features of the totally occluded lesions

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