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Article
Expression of RANKL by dental cells during eruption of mice teeth

Authors: Lubna K. Jassim لبنى جاسم --- Athraa Y. Al- Hijazi عذراء يحيى الحجازي
Journal: Journal of baghdad college of dentistry مجلة كلية طب الاسنان بغداد ISSN: 16800087 Year: 2013 Volume: 25 Issue: 1 Pages: 76-81
Publisher: Baghdad University جامعة بغداد

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Abstract

Background : In order for a tooth to erupt, two obvious requirements are needed. First, there has to be alveolar boneresorption of the bone overlying the crown of the tooth such that an eruption pathway is formed. Second, resorptionof bony crypt and apposition of new one, third, there has to be a biological process that will result in the toothmoving through this eruption pathway.The amniotic sac contains a considerable quantity of stem cells. Theseamniotic stem cells are multipotent and able to differentiate into various tissues, which may be useful for humanapplication. Receptor activator of nuclear factor kappa B ligand (RANKL) is concentrated on bone biology, morespecifically bone metabolism. RANKL plays a vital role in osteoclastogenesis for bone resorption. This study aimed toevaluate the expression of RANKL marker by dental cells during eruption of the teeth.Materials and Methods: : forty eight albino Swiss mice of one day old age injected with isolated amniotic stem cellsin the anterior region of maxilla (incisors area) other 16 mice injected with saline represents control. Sacrifice 4 micefor each period (4, 7, 10, and 13) day old age. The result were studied histologically and immunohistochemistry.Results: The present results localized and identified RANKL marker in 3 areas of developing tooth of the studied groupsincludes overlying, surrounding and apical bone. Positive RANKL with high significant value expressed by osteoclastof overlying bone in Amnion group followed by Control at day 4. In surrounding bone positive expression of RANKLillustrated to be highest in Control followed by Amniotic fluid at day 10.Apical bone shows positive expression ofRANKL in amniotic fluid group and it records to be the highest value in comparison to studied groups at day 10.Conclusion Expression marker RANKL illustrates that amniotic fluid group has a high expression of RANKL in osteoclastsurrounding and apical bone areas while control expressed RANKL in osteoclast of overlying bone. The present resultsopened clinical hopes in dental tissue engineering by application of autologous amniotic fluid and chorion cells

Keywords

RANKL --- tooth eruption


Article
Post Hair Epilation Acneiform Eruption Among Females

Authors: Khalifa E. Sharquie --- Haider R. Al-Hamami --- Inas K. Sharquie --- Adil A. Noaimi --- et al.
Journal: Iraqi Academic Scientific Journal المجلة العراقية للاختصاصات الطبية ISSN: 16088360 Year: 2013 Volume: 12 Issue: 2 Pages: 244-246
Publisher: The Iraqi Borad for Medical Specialization المجلس العراقي للاختصاصات الطبية

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Abstract

BSTRACT: BACKGROUND: Acneiform eruptions are common and important variants of acne vulgaris, there are many examples of acneiform eruptions like steroid acne and pityrosporum folliculitis. OBJECTIVE: To evaluate the acneiform eruption that follows hair epilation.PATIENTS AND METHODS: This case-series study was conducted in Department of Dermatology and Venereology, BaghdadTeaching Hospital during the period from January 2005 through July 2006. Forty females wereincluded in this work, history was taken from each patient and all were clinically examinedregarding all relevant points to this condition. Swabs and cultures from rash were carried out on11 patients using blood, chocolate, and McConky agar as culture media. RESULTS: The ages of patients ranged from14-40 years with a mean ± SD of 20.85 ± 5.52 years. History ofacne vulgaris was positive in 32 (80%) patients, and it was mild acne, resolved before the onsetof hair epilation acne. Method of hair epilation was threading and sugaring.The time intervalbetween hair epilation and rash appearance was 1-21 days with a mean ± SD of 4.48 ± 3.36 days.Itching was the commonest symptom complained by 18(45%) patients.The lesions morphologywas mainly monomorphous erythematous papules surmounted by tiny pustules. Swabs andcultures revealed no pathogenic bacteria. CONCLUSION: Hair epilation by threading and sugaring is a common cause of monomorphous acneiformeruption and might be an important triggering and exacerbating factor for acne vulgaris in Iraqifemales


Article
Immunohistochemical study of CD34 in tooth eruption by using amniotic stem cells

Authors: Lubna K. Jassim لبنى جاسم --- Athraa Y. Al- Hijazi عذراء الحجازي
Journal: Journal of baghdad college of dentistry مجلة كلية طب الاسنان بغداد ISSN: 16800087 Year: 2013 Volume: 25 Issue: 2 Pages: 47-53
Publisher: Baghdad University جامعة بغداد

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Abstract

Background: Tooth eruption is a more general process, however, which includes certain posteruptive toothmovements. There are two fundamental requirements for both tooth eruption to occur:(1) Require soft tissue, intervening between tooth structure and alveolar bone, which plays an important role inregulating the remodeling of adjacent tissues.(2) Require bone turnover that is temporally and spatially regulated to facilitate specific translocations of teeththrough alveolar boneThese amniotic stem cells are multipotent and able to differentiate into various tissues, which may be useful forhuman application and recently it used in many medical branches. CD34 is an endothelial marker that is extensivelyused in immunohistochemistry and most vascular endothelial cells. Expression of the stem cell antigen CD34 is adefining hallmark of hemopoietic stem cells and progenitors. This study aimed to study the expression of CD34 bydental cells involved in tooth eruption after administration of amniotic stem cellMaterials and Methods: forty eight albino Swiss mice of one day old age injected with isolated amniotic stem cells inthe anterior region of maxilla (incisors area) other 16 mice injected with saline represents control. Sacrifice 4 mice foreach period (4, 7, 10, and 13) day old age. The result were studied histologically and immunohistochemistry.Results: Immunohistochemical result revealed positive expression of CD34 in pulp (Vascular, Paravascular),Mesenchymal cell and in the Dental sac of different groups. Coincidence test of expression marker CD34 in variousstudied group shows that Chorion application affected on CD34 expression in pulp while Amniotic fluid affected ondental sac.Conclusion Immunohistochemical study of expression marker CD34 in various studied groups show that chorionapplication affected on CD34 in pulp .While amniotic fluid affected on dental follicle


Article
Eruption Time Estimation of Permanent 1st Molar, Central &, Lateral Incisors in 5.5 - 10 Years Age Children at Al Ramadi City / Iraq

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Abstract

The Parents consider tooth eruption as an important thing in thechild's life development, and they have often showed theirconcern about the timing of eruption of teeth. The purpose ofthis study were to Estimate the average age for eruption time ofPermanent 1st molar, central & lateral incisors in upper & lowerJaw (right & left) in both gender and to Compare the eruptiontime of these teeth between upper & lower Jaw ,right & left side,male &female. This study was conducted at Al Ramadi City /Iraq, where the sample was consisted of “786” children (391male & 395 female) of age 5.5 years to 10 years were theytaken randomly from various schools. Eruption of variouspermanent teeth (1st Molar, Central & Lateral Incisors teeth)were noted in both jaws and both sides. In our study we foundthat the permanent 1st molars were the first permanent tooththat erupts in all children at the age between 5.87 – 7.96 yearson both jaws and on both right and left sides with the mean ageof eruption at 6.57 ± 0.55 years in lower jaw and 6.62 ± 0.53years in upper jaw. In addition to that our study showed that thenext permanent teeth to erupt were central incisors which eruptat the age between 6.14 – 8.93 years on both jaws and on bothright and left sides with the mean age of eruption at 7.23 ± 0.61years in lower jaw and 6.29 ± 0.57 years in upper jaw. Finally,the eruption of permanent lateral incisors were at the agebetween 7.66 – 9.93 years on both jaws and on both right andleft sides with the mean age of eruption at 8.89 ± 0.56 years inlower jaw and 8.93 ± 0.55 years in upper jaw. The teeth eruptedin female earlier than male and in the lower Jaw than upperJaw. In the most cases the right lower teeth erupted earlier thanthe other quadrant of both jaws. In general, we found that therewas delay in the time of eruption of nearly all the teeth thatwere included in this study.


Article
Histometric Evaluation of Atenolol Effect on Developing Rat Dentition: Experimental Study

Author: Asmaa S Al-Douri
Journal: Al-Rafidain Dental Journal مجلة الرافدين لطب الأسنان ISSN: 18121217 Year: 2012 Volume: 12 Issue: 23 Pages: 153-159
Publisher: Mosul University جامعة الموصل

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Abstract

Aims: To investigate the histometric effect of atenolol drug on the developing dentition of rats. Mate-rials and Methods: The pregnant rats were divided into two main groups; control and atenolol treated groups. The control pregnant rats were given 1 ml distilled water orally from 12 – 18 day of gestation period, after delivery of these rats, thirty newborn rats from six mothers were sacrificed at ages 1, 5, 10 days postnataly (p.n). The experimental group were given 10 mg atenolol powder suspended in 1 ml distilled water orally, daily as a single dose from 12 – 18 day of gestation, thirty newborn rats from each six mothers were sacrificed at ages 1, 5, 10 days postnataly. The specimens were prepared for processing and staining with Hematoxyline and Eosin stains, and then examined by Motic microscope. Histometric measurements were under taken for these specimens by graticule lense. The histometric parameters used are the dentin thickness, mesiodistal dimension of molar teeth, pulp density (cellulari-ty) and eruption rate. Results: The results showed that atenolol affect on the developing rat dentition .This manifested by less dentin thickness, decreased mesiodistal dimension, increase in pulp cellularity and delay in eruption rate of lower incisor tooth in the atenolol treated groups in comparison to the con-trol groups. These observed changes are proceeded or continued as development process until last ex-premintal age 10 p.n. Conclusions: Atenolol drug delay the tooth development and affect it.


Article
Factors Influencing the Occurrence of Steroid acne
العوامل المؤثرة في حدوث العد الستيروئيدي

Authors: Salam Abdul Kareem Al-Temimi د. سلام عبد الكريم يوسف التميـمـي --- Hadaf Abed Al-Ameer د.هدف عبد الأمير
Journal: IRAQI JOURNALOF COMMUNITY MEDICINE المجلة العراقية لطب المجتمع ISSN: 16845382 Year: 2006 Volume: 19 Issue: 3 Pages: 265-267
Publisher: Al-Mustansyriah University الجامعة المستنصرية

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Abstract

AbstractBackground: Steroid acne is an acneoform eruption induced by steroids use. Steroid acne is relatively common dermatological problem, causing great cosmetic disfigurement.Objective: The study is aimed to evaluate several influencing factors on the occurrence of steroid acne. The factors to be assessed are age, sex, marital status, route of steroid administration, past history of acne, self-steroid prescription and type of occupation (outdoor/indoor).Patients & Methods: A case control study is performed. The study subjects were collected from Al-Yarmouk Teaching Hospital and private clinic. They were allocated into 2 groups in a ratio of 1:1. The cases group includes patients with steroid acne and controls group include patients with any steroid responsive dermatoses. The study period was from January 2002 until July 2002. Logistic regression analysis is used to examine the effect of the above-mentioned factors; their effect is expressed as odds ratios.Results: Seventy five steroid acne patients with a mean age of 20.8±4.5 years were collected and compared with a similar number of patients with any steroid responsive dermatosis as controls with a mean age of 30±10 years. Data analysis showed that the following factors contribute significantly to the increased incidence of steroid acne: sex (odds ratio: 3.95, P value: 0.009), route of steroid administration (odds ratio: 3.2, P value: 0.0319) and self drug prescription (odds ratio: 9.8, P value: 0.0002).Conclusion: The problem of injudicious use of topical and systemic steroids for cosmetic purposes is increasing in Iraqi society. This improper use of steroids reflects the increased incidence of steroid acne in Iraqi dermatology practice.Key words: Steroid acne, Acneoform eruption, influencing factors.

الملخص:الخلفية: العد الستيروئيدي هو طفح شبيه العد ناتج عن استعمال الستيروئيدات. العد الستيروئيدي اصبح نسبيا مرض جلدي شائع، والذي يؤدي إلى إتلاف جمالية الجلد بصورة كبيرة.الهدف: تهدف الدراسة إلى فحص عدة عوامل التي قد تؤثر في حدوث العد الستيروئيدي. العوامل هي العمر والجنس والحالة الزوجية و طريق استعمال الستيروئيدات والتاريخ السابق للعد والوصف الشخصي للستيروئيدات ونوع العمل (داخلي أو خارجي).الطريقة : أجريت دراسة نوع حالة ومقارنة. تم جمع المرضى من العيادة الخارجية للأمراض الجلدية في مستشفى اليرموك التعليمي والعيادة الخاصة. تم توزيع المرضى في مجموعين بنسبة 1:1. المجموعة الأولى تحتوي على المرضى المصابين بحالة العد الستيروئيدي. المجموعة الثانية (المقارنة) تحتوي على كل المرضى مصابين بأي مرض جلدي يعالج بالستيروئيدات. فترة الدراسة كانت من كانون الثاني للعام 2002 حتى تموز للعام 2002. استعمل التحليل الإحصائي اللوجستي لفحص العوامل المذكورة أعلاه وتأثيرها حُسب كنسبة الفائدة.النتائج: ادخل 75 مريض مصاب بالعد الستيروئيدي إلى الدراسة معدل أعمارهم 20±5‚4 سنة وقورنوا مع مجموعة مقارنة تستعمل الستيروئيدات لامراض جلدية أخرى تتضمن نفس العدد معدل أعمارهم 30±10 سنة. التحليل الإحصائي أثبت إن العوامل الآتية لها أهمية وهي الجنس (نسبة الفائدة 95‚3 قيمة P =0,009) وطريق استخدام الستيروئيد (نسبة الفائدة 3,2 قيمة P =0,0319) والوصف الشخصي للدواء (نسبة الفائدة 9,8 قيمة P =0,0002).الخاتمة: إن مشكلة الاستعمال الطائش للستيروئيدات الجهازية والموضعية لأغراض التجميل قد ازدادت في المجتمع العراقي. وهذا أدى إلى زيادة مرض العد الستيروئيدي كمرض جلدي في العراق.


Article
Examination of Third Molars Eruption Circumstances by OPG

Author: Ayman Hameed Uraibi
Journal: Medical Journal of Babylon مجلة بابل الطبية ISSN: 1812156X 23126760 Year: 2016 Volume: 13 Issue: 2 Pages: 398-404
Publisher: Babylon University جامعة بابل

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Abstract

Third molars or wisdom teeth, as they are more commonly known, are the teeth which are most often missing, impacted and with altered morphology.The aim of this study is to evaluate third molars eruption circumstances which include number, angulation, level, and amount of room for eruption of wisdom teeth per subjects.A total of 300 subjects (150 male and 150 female students within the age group of 17-26 years were selected . Any case who had history of extraction of any of the third molars or who rejected to give approval for participation were excluded, for each subject, panoramic imaging were obtained. The Results showed that the level of occlusal plane of third molar similar to that of adjacent tooth was seen in (40.79%)in male and (51.94)in female, also the results showed that 3.3%of the third molars were congenitally missing, and nearby (90.3%) of the students had all four third molars.0.66%had one third molars and 2%had two third molars, third molar agenesis showed no difference between male and female. Angulations position was maximum with vertical position in maxilla (73.45%) and mesio-angular position in mandible (41.6%) level of occlusal plane of third molar similar to that of adjacent tooth was seen in (45.8.%) in maxilla and (42.73%)in mandible. The present study concluded that panoramic imaging is a valuable radiographic modality in detection of third molars eruption variability.


Article
Panoramic study of third molar eruption for chronologic age assessment in Iraqi population

Authors: Dr. Amal R.S. Mohammed, B.D.S., H.D.D., M.Sc. Rad. د. امل رؤوف --- Dr. Nuhad Al. Hassan, B.D.S., M.Sc. Rad. د. نهاد الحسن
Journal: MUSTANSIRIA DENTAL JOURNAL مجلة المستنصرية لطب الاسنان ISSN: 18138500 Year: 2015 Volume: 12 Issue: 1 Pages: 88-97
Publisher: Al-Mustansyriah University الجامعة المستنصرية

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Abstract

Background: Age estimation plays a great role in forensic investigations,orthodontic, surgical treatment planning and tooth transplantation. The teeth areconsidered a reliable indicator of age and provide a number of parameters for ageprediction. The purpose of this study was to estimate the chronological age basedon the stages of mandibular third-molar eruption following the four stages givenby Olze et al.Materials and methods: The sample consist of 150 Iraqi subjects have been chosenwith known chronologic age (range: 6–26 years) and gender (70 males and 80female), digital panoramic radiograph had been taken for each examined subject .Olze et al. stages has been used to assess third molar eruption.Results: Alveolar and occlusal eruption at 25% of males younger than females . Ttestbetween gender for minimum age was statistically significant difference onlyin stage (B) with p-value (0.042).The deviation around normal value mean incomplete occlusal eruption was more in female compared with male.Conclusions: Radiographic evaluation of eruption stages of the third molars usingdental panoramic radiographies can be an efficient tool for chronological ageestimation in both forensic science and legal medicine. Complete occlusaleruption can be used to predict age equal or superior to 16 years.


Article
Time of Emergence of Permanent Teeth and Impact of Nutritional Status among 4-15 Years Old Children and Teenagers in Basrah City /Iraq

Authors: Hiyam S. Ahmed هيام احمد --- Zeyneb A. Al-Dahan زينب عبد الرضا الدهان
Journal: Journal of baghdad college of dentistry مجلة كلية طب الاسنان بغداد ISSN: 16800087 Year: 2016 Volume: 28 Issue: 4 Pages: 134-140
Publisher: Baghdad University جامعة بغداد

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Abstract

Background: The timing of eruption of permanent teeth is of considerable importance to the dental health planning for diagnostic, preventive and therapeutic measures for children and teenagers. The purposes of this study were to determine timing of maxillary and mandibular permanent teeth emergence (except third molars) and to evaluate the effect nutritional status by anthropometric measures on the eruption time of permanent teeth, investigations had been done according to jaw and gender variations.Materials and Methods: This study was conducted among four to fifteen years old children and teenagers from kindergarten and schools in Basrah city in the south region of Iraq. The total sample composed of 1807 children and teenagers that were collected randomly from kindergartens, primary and secondary schools in Basrah city.The data were statistically analyzed by using probit model in order to compute the median 5th and 95th percentile range of emergence. Athropmetric measures of height and weight were used for the purpose of assessment of nutritional status. The indices include: Weight for age, Height for age and Weight for height; each was considered as in term of standard deviation score (Z – score) as primary indicator of underweight, stunting and wasting respectively. The statistical significance of differences in mean of a normally distributed variable (nutritional indices z score) between 2 groups was assessed by independent samples t-test.Results: The results showed significant differences (p<0.05) between the timing of maxillary and mandibular teeth emergence in girls and boys, with earlier emergence in girls , also the mandibular teeth emerge before their maxillary opposing teeth in both sexes except for premolars .The prevalence of malnutrition according to height for age, weight for age, and weight for height nutritional status indicators were found to be 7.4 %, 3.7 % and 1.5% respectively.The results showed that among well-nourished children and teenagers described by height for age nutritional status indicator, most teeth were significantly erupted earlier than stunted except the lateral incisor which erupted earlier in stunted boys than well-nourished boys but the difference was not significantly accepted. The greatest difference of median eruption age of permanent teeth between well -nourished and stunted found in girls in the second molar tooth.Conclusions: Records indicated that the Iraqi children exhibit variation in their times of permanent teeth emergence when compared with other studies, and among well-nourished children and teenaged described by height for age nutritional status indicator, most teeth were significantly erupted earlier than stunted children and teenagers


Article
Distribution and Prevalence of Various Developmental Dental Anomalies in Iraqi population : A Radiographic Study.

Author: Dr. Amal R.S. Mohammed. B.D.S. , H. D.D., M.Sc. Rad د. امل رؤوف
Journal: MUSTANSIRIA DENTAL JOURNAL مجلة المستنصرية لطب الاسنان ISSN: 18138500 Year: 2017 Volume: 14 Issue: 1 Pages: 137-146
Publisher: Al-Mustansyriah University الجامعة المستنصرية

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Abstract

Aim: To determine the prevalence of dental anomalies in Iraqi population, andinvestigate their possible association with gender and teeth.Materials and methods: Panoramic radiographs of 800 patients out of 350 withdental anomalies (200 females and 150 males) ,an age range of 18–30 years ( 300: 18-25 years ; 50: 25-30 years ) were examined for anomalies in teeth number,shape, size and position.Descriptive statistics was performed using SPSS. Thelevel of significance was set at 95% confidence level.Results: Among the 800 radiographs examined, a total of 350 (43.8 %) haddevelopmental dental anomalies which includes 150 (42.9%) males and 200(57.1%) females. Around 290 (82.9%) had at least one anomaly, 50 (14.2%) caseswith two anomalies and only 10 (2.9%) exhibited more than two anomalies. Bothmales and females were equally affected. Of these 350 anomalies, 300 (85.7%)occurred in the age group 18–25 years compared to 50 (14.3%) cases in 25–30years range .Conclusion: The high prevalence of Developmental Dental Anomalies suggests theneed to increase the understandingof their etiology and aid for better management,intervention and prevention.

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