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TOPICAL ACTIVITY OF_ Aloe vera (/Lverla ) EXTRACT ON EXCISION WOUND—HEALlNG OF SKIN IN RABBITTS:CLINICAL ANDA HISTOLOGICAL STUDY
فعالية مستخلص نبات الصبار في علاج الجروح الجلدية القطعية في الارانب البرية: دراسة سريرية نسيجية

Author: A.A..Sawad علاء عبد الخالق سواد
Journal: Basrah Journal of Veterinary Research. مجلة البصرة للابحاث البيطرية ISSN: Print:18138497 E; 24108456 Year: 2006 Volume: 5 Issue: 2 Pages: 160-169
Publisher: Basrah University جامعة البصرة

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Abstract

plant /I/ac van: is a green succulent .cactus-like plant belonging to the lily family,The.plant has a history of use in folk medicine for skin and otherdisorders. The objective ofthe study presented in this report was to screen the extracts of this plant for its wound-- healing properties based on its traditional use for wound healing. ethanolic extracts wasprepared for topical applications. The dose used was 150 mg/kg daily for 10 days, using theexcision wound model in rabbits. Carboxymethyl cellulose (1%) was used as control in . ‘topical studies. Animals were randomized divided to treatment or control groups, . Woundareas were measured. At the day Il',skin .tissue was excised for histological studies" .Wound areas reduced significantly in all treatment groups compared to respective controls (P< .001). Histology outcomes were consistent with changes in the treatment groups. Nodifferences were detected within the treatment groups. The study permits the conclusion thatAloe Vera has wound—hea‘ling potential

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