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Article
Prevalence of upper gastro intestinal endoscopy findings in endoscopy referred patients at Mosul city, a ten years retrospective study

Author: Makkie A.K. AL-Youzbaki مكي اليوزبكي
Journal: Annals of the College of Medicine Mosul مجلة طب الموصل ISSN: 00271446 23096217 Year: 2010 Volume: 36 Issue: 1&2 Pages: 8-11
Publisher: Mosul University جامعة الموصل

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Abstract

Objectives: To analyze the findings of upper GI endoscopic examination carried out in order to assess the prevalence of upper GI disorders in the examined patients.
Design and setting: A retrospective clinical case series study done over a 10 years period from the 1st of October 1998 to the 1st of October 2008, at the Endoscopy Unit of Al Salam Teaching General Hospital during which a total of three thousand seven hundreds and nineteen upper GI endoscopic examinations were performed and analyzed.
Results: The mean age of our patients was 39.8 years and male to female ratio was 1.29:1 (males 56% and females 44%). Out of the total number of patients (3719), a sum of 1322 (35.5%) patients were typed as normal on endoscopic assessment while 2397 (64.5%) patient were found to retain abnormal findings with the duodenal lesions being the commonest 64%, followed by esophageal one 19%, then gastric lesions 17%. Duodenal ulcer was the most frequently recovered pathology [689 (29%) patients] followed by duodenitis [483 (20%) patients], then by gastroesophageal reflux disease [363 (15%) patients] that is followed by gastritis [312 (13%) patients].
Conclusions: Upper GI lesions are frequent in Mosul population. The upper GI endoscopy is a valuable mean in the assessment of upper GI symptomatology.

Keywords: GI, gastrointestinal.

الأهداف: لتحليل نتائج تنظير الجهاز الهضمي العلوي الذي تم إجراؤه في شعبة التنظير لتقييم أنواع انتشار أمراض الجهاز الهضمي العلوي للمرضى المحالين.التصميم والاعداد: تم إجراء دراسة لسلسلة من الحالات السريرية الاسترجاعية والتي امتدت لفترة عشر سنوات ابتداءا من شهر تشرين أول 1998 ولغاية الأول من شهر تشرين أول 2008 في شعبة التنظير التابعة لمستشفى السلام التعليمي العام حيث تم خلال هذه الفترة فحص وتحليل ثلاثة آلاف وسبعمائة وتسعة عشر حالة.النتائــج: كان متوسط عمر المرضى 39,8 سنة وبلغت نسبة الذكور الى الاناث 1,29:1 (الذكور 56% والإناث 44%) من المجموع الكلي لعدد المرضى البالغ (3719)، وتم تصنيف ما مجموعه منها 1322 (35,5%) كانت طبيعية أثناء الفحص، في حين وجد بان باقي المرضى البالغ عددهم 2397 (64,5%) كانت حالات مرضية كما يلي، أمراض ألاثني عشري كانت الأكثر شيوعا (64%) تليها أمراض المريء وكانت نسبتها (19%) وأخيرا أمراض المعدة وبلغت نسبتها (17%). قرحة ألاثني عشري كانت هي الأكثر انتشارا حيث كان عدد المرضى المصابين بها [689(29%)] يليها التهاب ألاثني عشري [483(20%)] ويليها المرضى المصابين برخاوة الفتحة الفؤادية [363(15%)] ويليها أخيرا أمراض التهاب المعدة حيث بلغ عددهم [312(13%)].الاستنتاجات: تعتبر أمراض الجهاز الهضمي العلوي شائعة ومنتشرة بين المرضى في مدينة الموصل. ويعتبر فحص تنظير الجهاز الهضمي العلوي أحد أهم الوسائل في تقييم مرضى الجهاز الهضمي العلوي.

Keywords

GI --- gastrointestinal


Article
Malignant Gastrointestinal Stromal Tumors of the Stomach

Author: Zuhair Raof Al-Bahrani
Journal: Iraqi Academic Scientific Journal المجلة العراقية للاختصاصات الطبية ISSN: 16088360 Year: 2008 Volume: 7 Issue: 3 Pages: 196-200
Publisher: The Iraqi Borad for Medical Specialization المجلس العراقي للاختصاصات الطبية

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Abstract

ABSTRACT:BACKGROUND:Stromal or mesenchymal neoplasms affecting the gastrointestinal (GI) tract are divided into two groups. The less common variety includes tumors that are identical to those that arise in the soft tissues throughout the rest of the body, including lipomas, schwannomas, hemangiomas. The second more common group consists of stromal tumors that are collectively referred to as gastrointestinal stromal tumors (GISTs).They are most often located in the stomach and proximal small intestine.OBJECTIVE:To compare the incidence, mode of presentation and management of malignant gastric GISTs of this study from Iraq with other world reports.METHODS:Retrospective study of the medical records of 1037 patients with gastric malignancies operated upon between January 1970-December 2000 were reviewed. The incidence of GISTs , their age and sex, symptomatology, diagnostic procedures, surgical management and results will be presented.RESULTS:Among 1037 patients with gastric malignancies, 13 (1.25%) were malignant GISTs. 6 were males and 7 females. Age ranges from 19-67 (median 58 +/- 13 .2397 SD) years. Mode of presentation were; upper GI bleeding 8(62%), dyspepsia 4(31%) and mass one (8%) patient. Duration of illness ranges from 2 days-8 years (median 3 months+/- 25.9207 SD ). Barium study revealed a tumor in 10 out of 11 patients. Endoscopy in 12 patients reported 4 nodular, 3 fungating and 3 ulcerative tumor and two normal. Ultrasound in 8 patients showed a mass in 7(5 intraluminal, two extraluminal) and no tumor in one. Site of tumor were the; lesser curve 4(31%), antrum 3(23%), greater curve 2(15%), fundus 2(15%), body one (8%) and cardia one (8%) patient. Grossly the tumors were; fungating 5, nodular 2, ulcerative one, nodular-cystic 3 and nodular-ulcerative in 2. The tumor size vary from 5x3 – 17x12 (mean 9.69231 +/- 3.727793 SD x 7.69231 +/- 2.95479 SD) cm.Gastric resections were; upper 5, segmental 4, subtotal 2 and lower 2 patients. Chemotherapy and/or radiotherapy were given to advance or those with metastasis. Histopathology reported low-grade malignancy in 5 and high-grade in 8 patients. According unified 1997 TNM staging were; I 2, II 4, III 3 and IV 4 cases. Two-years survival was 69% (9 out of 13) and 5-years was 46% (6 out of 13). CONCLUSION:Malignant GISTs constitute 1.25 % of all gastric malignancies. No gender predilection found. Median age 50.3 years. Recurrent upper GI bleeding in 62% and dyspepsia in 31%. No specific symptoms but abdominal mass in 4 cases. Barium study, endoscopy and US were the diagnostic procedures. Tumors were; mostly intraluminal, fungating nodular and large (median 8x8 cm). Resection was the treatment. 5 were low-grade and 8 high-grade malignancy. 2 and 5-years survival were 62% and 46% respectively.


Article
Are Indications For Esophago Gastro Duodenoscopy Properly Followed?

Authors: Zuhair B Kamal زهير كمال --- Mohammed A Al-Atroshi محمد التروشي --- aad H Sultan سعد سلطان --- Wisam A Hussein وسام حسين
Journal: Al-Kindy College Medical Journal مجلة كلية الطب الكندي ISSN: 18109543 Year: 2011 Volume: 7 Issue: 1 Pages: 56-60
Publisher: Baghdad University جامعة بغداد

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Abstract

Background: Symptoms related to the upper gastro-intestinal tract are very common. Attribution of these symptoms to upper G. I. T.diseases are usually done on clinical bases, which could be confirmed by Esophago Gastro Duodenoscopy (EGD). The use of such tools might increase the diagnosis accuracy for such complaints. The indications for upper G I endoscopy might decrease the negative results of endoscopies.Objective: To follow strict indications for Esophago Gastro Duodenoscopy in order to decrease the negative endoscopy results. Methods: One thousand eight hundred and ninety cases were subjected to EGD from Feb. 1999 to Feb 2009 at Alkindy Teaching Hospital and Abd-Al-Majeed private hospital in Baghdad, Iraq. A special endoscopy unit form was prepared containing data from patients, clinical complaint, indications for endoscopy request, and the endoscopic diagnosis, biopsies were taken when indicated and subjected to histopathological examination. All these data were studied and analyzed.Results: Out of the total 1890 patients there were 1114 males and 776 females with male to female ratio 3/2, the most common age group ranged from 21 to 50 years with a mean age of 32 years. Upper abdominal pain was the most common indication (30%), upper GI bleeding (27.94%), duodenal ulcer follow up (25.5%). The diagnosis of chronic DU was established in (40.21%) of cases, normal endoscopic results were found in (34.6%), duodenitis and gastritis in (15.2%).Conclusion: The high number of normal gastrointestinal endoscopies necessitates the need to follow strict indications before subjecting the patients for endoscopy.


Article
Gastrointestinal Tuberculosis: Retrospective Review of 86 Cases

Author: Zuhair R Al-Bahrani
Journal: Iraqi Academic Scientific Journal المجلة العراقية للاختصاصات الطبية ISSN: 16088360 Year: 2007 Volume: 6 Issue: 3 Pages: 169-183
Publisher: The Iraqi Borad for Medical Specialization المجلس العراقي للاختصاصات الطبية

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Abstract

ABSTRACT:BACKGROUND:The aim of this study is to present our experience in the management of gastrointestinal tuberculosis in Iraq.PATIENTS&METHODS:86 cases with intestinal tuberculosis were histologically proven by endoscopy or surgery, during the period 1965-2004 at the Medical City Teaching Hospital, & two private hospitals (Alousi & Mustansiria), Baghdad.RESULTS:54(62.8%) were female and 32(37.2%) were male. Age ranged from 6-82 years (mean 33yrs), peak 30-39 years. Clinical presentation were; intestinal obstruction 44(51.2%), abdominal mass 20(23.3%), malabsorption 13(13%), massive gastrointestinal bleeding 3(3.5%), peritonitis 3(3.5%), pyloric obstruction 2(2.3%) and dysphagia 1(1.2%) patients. Chest X-ray reported; normal in 62(72.1%), active pulmonary tuberculosis in 3(3.5%), and healed lesion in 21(24.4%) patients. Barium study revealed dilated bowel loops in 31(45.6%); other less frequent findings were strictures, filling defect, shortening and bowel irregularity. OGD showed a significant pathology in 7 out of 11 patients examined. Ultrasound showed helpful imaging modality in 15/21 patients; ascitis, masses, enlarged lymph nodes, and thick bowel loops in some cases. Site of lesions were; ileocecal 42(48.8%), small bowel 33(38.4%), colorectal 8(9.3%) and stomach 3(3.5%) patients. Gross appearance were hyperplastic 33(38.4%), ulcerative 20(13.9%), strictures 21(24.4), and mixed 12 (13.9%) patients. Surgical procedures were; right hemicolectomy 38(44.2%), resection of small bowel 23(26.7%), colectomy 4(4.7%), by-pass 4(4.7%), stricturoplasty 2(2.3%), and subtotal gastrectomy 1(1.2%) and biopsy only 14(16.3%) patients. One patient died post-operatively from pulmonary embolism, 6 lost to follow, 4 had relapse after stopped treatment within 3-5 months (one of them died from intestinal obstruction) while the result in those followed 74 (including 3 who relapsed and re-treated) patients whom received chemotherapy for over one year were very satisfactory.CONCLUSION:Gastrointestinal tuberculosis affects females more than males. No age is immune, peak in 3rd decade. Symptomatology is non-specific, it should be suspected in patients having abdominal pain, weight loss, anorexia, fever, ascites and abdominal mass. Sub-acute or acute intestinal obstruction is the most common presentation followed by abdominal mass or malabsorption in our study. Normal chest radiograph does not exclude the presence of abdominal tuberculosis, but it should be suspected in high ESR patients. Surgical interventions is not alternative to standard anti-tuberculous therapy


Article
The Role of Dientamoeba fragilis in Children with Gastrointestinal Illness

Author: Sabah. A. Al-Najar
Journal: Iraqi Academic Scientific Journal المجلة العراقية للاختصاصات الطبية ISSN: 16088360 Year: 2006 Volume: 5 Issue: 1 Pages: 42-45
Publisher: The Iraqi Borad for Medical Specialization المجلس العراقي للاختصاصات الطبية

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Abstract

ABSTRACT: BACKGROUND: Dientamoeba fragilis is an intestinal protozoa whose pathogenic characteristics are increasingly recognized. AIM OF THE STUDY: The aim of this study is to specify the clinical, biological and epidemiological aspects of D.fragilis among children with gastrointestinal illness. METHODS: This study was conducted on 171 children attending Child Welfare Teaching Hospital for Pediatrics over a period of 8 months. Stool samples of each child were processed for direct wet smear, modified acid fast and Giemsa staining procedures. RESULTS: D. fragilis was observed in 41 (23.4%) case, 39(31.2%) among patients group and 1(2.2%) among control group. This parasite was predominant 15(28.5%) among age group (1-3) years. D. fragilis was associated with other intestinal parasites particularly Blastocystis hominis 8(20.5%), Entamoeba histolytica 5(12.8%), Enterobius vermicularis 3(7.7%) and Giardia lamblia 2(5.1%). Clinical signs included abdominal pain 31(79.4%), diarrhea 20(51.3%), anorexia 4(35.9%), fever 11(28.2%) and alternating of diarrhea and constipation 10(25.6%). DISCUSSION: D.fragilis is today classified in the group of flagellates and I share the opinion of the majority of the authors as to its real pathogenic capacity.


Article
ECG CHANGES DURING UPPER GASTROINTESTINAL TRACT ENDOSCOPY (A PROSPECTIVE STUDY)

Authors: Mutez Nahi Mansur --- Issam Merdan --- Ali Raheem --- Mazin Hawaz Al Hawaz
Journal: Basrah Journal of Surgery مجلة البصرة الجراحية ISSN: 16833589 / ONLINE 2409501X Year: 2006 Volume: 12 Issue: 1 Pages: 86-91
Publisher: Basrah University جامعة البصرة

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This study aimed to evaluate the cardiac changes and complications that occurred in patients who underwent upper gastrointestinal tract endoscopy. The study was conducted from January 2002 to December 2002at Basrah General Hospital and Al-Sadir Teaching Hospital. One hundred and forty eight patients complaining of upper gastrointestinal tract disorders were included in this study. Detailed history, physical examination and ECG was taken before, during and half hour after endoscopic examination. Patients were divided into two groups according if they have previous cardiopulmonary diseases.One hundred and forty eight patients included in the study, 91 males and 57 females. The age group between 20–40 years represent the commonest group underwent oesophago-gastroduodenoscopy (O.G.D) examination.All ECG changes that developed in patients before endoscopic examination arise from those who had cardiopulmonary diseases. Forty-two (40.4%) and 21 (47.7%) patients from group I. and group II. respectively showed abnormal ECG changes while 18 (17.3%) and 13 (29.5%) patients from group I. and group II. respectively showed abnormal ECG findings half hour after endoscopic examination . Bradycardia represents the commonest ECG changes occurred during and half hour after examination. We concluded that OGD is a safe procedure but in elderly patients and those with cardiopulmonary disease ECG monitoring should be done during endoscopic examinationBas J Surg, March, 12, 2006

Keywords

ECG --- GASTROINTESTINAL --- ENDOSCOPY


Article
NUTRITION IN GASTROINTESTINAL SURGICAL PATIENTS

Author: Majeed H Alwan
Journal: Basrah Journal of Surgery مجلة البصرة الجراحية ISSN: 16833589 / ONLINE 2409501X Year: 2009 Volume: 15 Issue: 2 Pages: 10-15
Publisher: Basrah University جامعة البصرة

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Despite important advances in surgical care and minimized surgical trauma, postoperativecomplications are still of great concern. Nutritional depletion has been demonstrated to be amajor determinant in the development of postoperative complications. Nutritional status ofgastrointestinal surgical patients is an important issue, which need to be attended in particularlyduring the perioperative period.Fears of postoperative ileus and the integrity of the newly constructed anastomosis have led tothe adoption of starvation with administration of intravenous fluids until the return of normalbowel sounds and passage of flatus. However, it has been shown that early postoperativeenteral feeding is both beneficial and well-tolerated.Meta-analysis has shown that enteral feeding compared with parenteral nutrition is associatedwith fewer complications, reduced costs and a shorter hospital stay. Therefore it should be thepreferred option whenever possible.Evidence to support preoperative nutrition is limited, but malnourished individuals fed for 7-10days preoperatively may have improved surgical outcome.Prolong preoperative starvation is not essential, and the administration of preoperativecarbohydrates is safe without the fear of increasing the risk of aspiration.Initially nutritional support was aimed at meeting the energy needs and providing proteins andother essential micronutrients, while now it is more directed at modulation of the immunefunctions, the so called immunonutrition.Multimodal strategies including minimal invasive surgery, adequate postoperative analgesia,nutritional care, and enforced mobilization resulted in reduction in postoperative complicationsand length of hospital stay.


Article
EVALUATION OF LACTOBACILLUS SALIVARUS AS
تقييم العصيات اللبنية اللعابية كمعزز حيوي في الكلاب

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Abstract

Lactobacillus salivarus has been studied extensively as a probiotic in human . However the ability of an organism to survive passage through the intestinal tract and exert beneficial effects can not be directly extrapolated between species. This study evaluated the ability of L.salivarus to survive gastrointestinal transit in dogs and assessed whether oral administration of L.salivarus is safe in order to determine whether studies evaluating the efficacy of L.salivarus in the treatment of canine disease are indicated. Dogs were divided into 5 groups receiving doses of 0 (control group n=8),1 109 (group 1, n=8), 1 1010 ( group2 ,n=8) , 5 1010 (group3, n=8) and 5 1011 (group 4,n=8) colony forming unite per day orally for 5 days. L.salivarus was detected in the feces of 3/8 dogs in group 1 and 2, 4/8 dogs in group 3; 8/8 dogs in group 4 and 0/8 dogs in control group. Fecal colonization was significantly greater in group 4 than in any other groups (P> 0.01). Differences between groups 1,2 and 3 were not significant. No adverse effects were noted. Fecal colonization of L.salivarus in dogs is somewhat variable; however clinical studies are indicated to evaluated this organism in the treatment and prevention of canine disease.

الخــلاصــةدرست العصيات اللبنية اللعابية كمعزز حيوي في الإنسان بصورة مفصلة وعلى آية حال فأن قدرة هذه الجراثيم على مقاومة المرور خلال القناة الهضمية وبالتالي إعطاء تأثيرها الفعال تختلف بين الحيوانات لذلك فقد أجريت هذه الدراسة لتقييم قدرة العصيات اللبنية اللعابية على البقاء والانتقال عبر القناة الهضمية للكلاب عند إعطاءها عن طريق الفم وكذلك لمعرفة ما إذا كان استعمال هذه الجراثيم امين عند إعطائها عن طريق الفم وبالتالي للتوصية باستخدامها في علاج أمراض القناة الهضمية في الكلاب. استعمل في هذه الدراسة (40) كلب بالغ قسمت إلى خمسة مجاميع ضمت كل مجموعة ثمان حيوانات وأعطيت هذه المجاميع صفر ( مجموعة السيطرة) ،1 910 (المجموعة الأولى) ،1 1010 ( المجموعة الثانية) ،5 1010 (المجموعة الثالثة) و5 1110 (المجموعة الرابعة) جرثومة /يومياً عن طريق الفم لمدة خمسة أيام .عزلت العصيات اللبنية اللعابية من ثلاث من اصل ثمان حيوانات لكل من المجاميع الأولى والثانية ومن 4 من 8 حيوانات في المجموعة الثالثة ومن جميع الحيوانات المجموعة الرابعة ولم تعزل من أي حيوان من حيوانات مجموعة السيطرة. أن أعداد الجراثيم المتواجدة في البراز كانت أعلى بصورة معنوية في حيوانات المجموعة الرابعة مقارنة مع المجاميع الأولى والثانية والثالثة (0.01 > P) ولم تلاحظ فروقات معنوية بين المجاميع الثلاث الأولى. أن عدد هذه الجراثيم في البراز يختلف من حيوان لأخر لذا نقترح أجراء دراسة سريرية لتقييم استخدام هذه الجراثيم في العلاج والوقاية من أمراض القناة الهضمية في الكلاب.


Article
EVALUATION OF LACTOBACILLUS SALIVARUS AS
تقييم العصيات اللبنية اللعابية كمعزز حيوي في الكلاب

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Abstract

Lactobacillus salivarus has been studied extensively as a probiotic in human . However the ability of an organism to survive passage through the intestinal tract and exert beneficial effects can not be directly extrapolated between species. This study evaluated the ability of L.salivarus to survive gastrointestinal transit in dogs and assessed whether oral administration of L.salivarus is safe in order to determine whether studies evaluating the efficacy of L.salivarus in the treatment of canine disease are indicated. Dogs were divided into 5 groups receiving doses of 0 (control group n=8),1 109 (group 1, n=8), 1 1010 ( group2 ,n=8) , 5 1010 (group3, n=8) and 5 1011 (group 4,n=8) colony forming unite per day orally for 5 days. L.salivarus was detected in the feces of 3/8 dogs in group 1 and 2, 4/8 dogs in group 3; 8/8 dogs in group 4 and 0/8 dogs in control group. Fecal colonization was significantly greater in group 4 than in any other groups (P> 0.01). Differences between groups 1,2 and 3 were not significant. No adverse effects were noted. Fecal colonization of L.salivarus in dogs is somewhat variable; however clinical studies are indicated to evaluated this organism in the treatment and prevention of canine disease.

الخــلاصــةدرست العصيات اللبنية اللعابية كمعزز حيوي في الإنسان بصورة مفصلة وعلى آية حال فأن قدرة هذه الجراثيم على مقاومة المرور خلال القناة الهضمية وبالتالي إعطاء تأثيرها الفعال تختلف بين الحيوانات لذلك فقد أجريت هذه الدراسة لتقييم قدرة العصيات اللبنية اللعابية على البقاء والانتقال عبر القناة الهضمية للكلاب عند إعطاءها عن طريق الفم وكذلك لمعرفة ما إذا كان استعمال هذه الجراثيم امين عند إعطائها عن طريق الفم وبالتالي للتوصية باستخدامها في علاج أمراض القناة الهضمية في الكلاب. استعمل في هذه الدراسة (40) كلب بالغ قسمت إلى خمسة مجاميع ضمت كل مجموعة ثمان حيوانات وأعطيت هذه المجاميع صفر ( مجموعة السيطرة) ،1 910 (المجموعة الأولى) ،1 1010 ( المجموعة الثانية) ،5 1010 (المجموعة الثالثة) و5 1110 (المجموعة الرابعة) جرثومة /يومياً عن طريق الفم لمدة خمسة أيام .عزلت العصيات اللبنية اللعابية من ثلاث من اصل ثمان حيوانات لكل من المجاميع الأولى والثانية ومن 4 من 8 حيوانات في المجموعة الثالثة ومن جميع الحيوانات المجموعة الرابعة ولم تعزل من أي حيوان من حيوانات مجموعة السيطرة. أن أعداد الجراثيم المتواجدة في البراز كانت أعلى بصورة معنوية في حيوانات المجموعة الرابعة مقارنة مع المجاميع الأولى والثانية والثالثة (0.01 > P) ولم تلاحظ فروقات معنوية بين المجاميع الثلاث الأولى. أن عدد هذه الجراثيم في البراز يختلف من حيوان لأخر لذا نقترح أجراء دراسة سريرية لتقييم استخدام هذه الجراثيم في العلاج والوقاية من أمراض القناة الهضمية في الكلاب.


Article
EVALUATION OF LACTOBACILLUS SALIVARUS AS
تقييم العصيات اللبنية اللعابية كمعزز حيوي في الكلاب

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Abstract

Lactobacillus salivarus has been studied extensively as a probiotic in human . However the ability of an organism to survive passage through the intestinal tract and exert beneficial effects can not be directly extrapolated between species. This study evaluated the ability of L.salivarus to survive gastrointestinal transit in dogs and assessed whether oral administration of L.salivarus is safe in order to determine whether studies evaluating the efficacy of L.salivarus in the treatment of canine disease are indicated. Dogs were divided into 5 groups receiving doses of 0 (control group n=8),1 109 (group 1, n=8), 1 1010 ( group2 ,n=8) , 5 1010 (group3, n=8) and 5 1011 (group 4,n=8) colony forming unite per day orally for 5 days. L.salivarus was detected in the feces of 3/8 dogs in group 1 and 2, 4/8 dogs in group 3; 8/8 dogs in group 4 and 0/8 dogs in control group. Fecal colonization was significantly greater in group 4 than in any other groups (P> 0.01). Differences between groups 1,2 and 3 were not significant. No adverse effects were noted. Fecal colonization of L.salivarus in dogs is somewhat variable; however clinical studies are indicated to evaluated this organism in the treatment and prevention of canine disease.

الخــلاصــةدرست العصيات اللبنية اللعابية كمعزز حيوي في الإنسان بصورة مفصلة وعلى آية حال فأن قدرة هذه الجراثيم على مقاومة المرور خلال القناة الهضمية وبالتالي إعطاء تأثيرها الفعال تختلف بين الحيوانات لذلك فقد أجريت هذه الدراسة لتقييم قدرة العصيات اللبنية اللعابية على البقاء والانتقال عبر القناة الهضمية للكلاب عند إعطاءها عن طريق الفم وكذلك لمعرفة ما إذا كان استعمال هذه الجراثيم امين عند إعطائها عن طريق الفم وبالتالي للتوصية باستخدامها في علاج أمراض القناة الهضمية في الكلاب. استعمل في هذه الدراسة (40) كلب بالغ قسمت إلى خمسة مجاميع ضمت كل مجموعة ثمان حيوانات وأعطيت هذه المجاميع صفر ( مجموعة السيطرة) ،1 910 (المجموعة الأولى) ،1 1010 ( المجموعة الثانية) ،5 1010 (المجموعة الثالثة) و5 1110 (المجموعة الرابعة) جرثومة /يومياً عن طريق الفم لمدة خمسة أيام .عزلت العصيات اللبنية اللعابية من ثلاث من اصل ثمان حيوانات لكل من المجاميع الأولى والثانية ومن 4 من 8 حيوانات في المجموعة الثالثة ومن جميع الحيوانات المجموعة الرابعة ولم تعزل من أي حيوان من حيوانات مجموعة السيطرة. أن أعداد الجراثيم المتواجدة في البراز كانت أعلى بصورة معنوية في حيوانات المجموعة الرابعة مقارنة مع المجاميع الأولى والثانية والثالثة (0.01 > P) ولم تلاحظ فروقات معنوية بين المجاميع الثلاث الأولى. أن عدد هذه الجراثيم في البراز يختلف من حيوان لأخر لذا نقترح أجراء دراسة سريرية لتقييم استخدام هذه الجراثيم في العلاج والوقاية من أمراض القناة الهضمية في الكلاب.

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