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Article
THE POSSIBLE RELATION BETWEEN HELICOBAC T ER PYLORI I INFECTION WITH_ BLOOD GROUPS , ANEMIA ANDPERIPHERAL LYMPHOCYTE ELEVATION A
العلاقة الممكنة بين الاصابة بجرثومة الملوية البوابية ومجاميع الدم وارتفاع مستويات الخلايا اللمفاوية المحيطية

Author: Zenaa W.Atean زينة وحيد عطوان
Journal: Basrah Journal of Veterinary Research. مجلة البصرة للابحاث البيطرية ISSN: Print:18138497 E; 24108456 Year: 2006 Volume: 5 Issue: 2 Pages: 83-87
Publisher: Basrah University جامعة البصرة

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Abstract

Biopsy were taken from 50 patients in order to cultivate Helicobacter pylori andblood samples to detect anemia , differential white blood eellcount and blood groups .The results showed that anemia was found in 48% of the patients while lymphocyteelevated in 44% of them , blood group 0 had the higher percentage ( 42% ) in thosepatients among the other blood group types" . ' . _ _INTRODUCTION -Helicobacter pylori is a gram-negative microorganism that secretes manysubstances including ammoina , mucolytic enzymes ( adhesins , catalase and urease ) andacid secrete inhibitory proteins.(8) In addition to that it secrets toxin like vacuolatingcytotoxin A (vacA).(7). - —Adhesin allows the organism to adhere , catalase might protect the organisum fromthe immune system , urease increase the secretion of gastrin which stimulate the intestinal‘tissues to grow faster , and so could result in increased cancer risk .Urease is reponsible forhydrolyzing urea to NH3 and CO2, and acts as also protective by forming an alkalinenvironment around the organism . The combination of NH3 ,_Co2 and inhibitory proteinsallows the bacteria to setup locallized pockets where it can neutralize even the acidity of' blood type 0 stomachsThe genetics of the secretor and non —-secretor system interact to alter anindividuals risk for ulcer. In several studies , non—secretors of ABO substances have beenfound to have significantly higher rate ofduodenal and peplic ulcer .( 8)fl._ pylori infection increases the percentage of peripheral lymphocytes above theupper limit of referential.values .(l0)e ' ‘Recent evidence suggests that fl_. pylori infection could cause iron deficiencyanemia ( IDA ).(2). Adolescent femal athletes may have development of [_{_.__pyloriassociated ( IDA ) which can be managed by Q pylori eradication (5 ) . H. pylori mayhave a role in causing IDA in school-age children (3 )

Keywords

Anemia --- Gastrin --- Urea


Article
The Relationship between Gastrin Hormone and Fasting Blood Sugar Levels in Patients with Diabetes Mellitus Type 2

Authors: Haider.K.Zaidan --- Moshtak.A.Wtwt --- Nawras.N.Allawae
Journal: Journal of University of Babylon مجلة جامعة بابل ISSN: 19920652 23128135 Year: 2016 Volume: 24 Issue: 2 Pages: 344-349
Publisher: Babylon University جامعة بابل

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Abstract

This study dealing with diabetic type 2 patients to estimate the relationship of gastrin hormone level and the fasting blood sugar in diabetic patients from plasma of blood, A total samples of this study consist of (n=67) of diabetic type 2 patients & 25 control. In this study the patients was divided in to three groups according the duration of diabetic,the percentage of patients who have duration of diabetes less than 10 years 34.4% (n=23) as 1st group, less than 20 years more than 10 years 32.8% (n=22) as 2nd group and equal or more than 20 years 32.8% (n=22) as 3rd group ,all samples test and control analysis the fasting blood sugar by chemical reagent (glusenate) and the reagent readied by spectrophotometer while the gastrin hormone level was analyses by enzyme immunosorbent assay (ELISA) kit, This Enzyme immunosorbent assay kit is designed to detect a specific peptide and its related peptides based on the principle of “competitive” enzyme immunoassay. The results of gastrin hormone were readied by ELISA. Analysis was carried out using SPSS version 18. Categorical variables were presented as frequencies and percentages. There is significant differences( pهذه الدراسة تهتم بالمرضى المصابين بداء السكري النوع الثاني لتقدير علاقة مستوى هرمون الكاسترين مع قيمة سكر الدم قبل الافطار من بلازمة مرضى السكري , العدد الكلي للعينات في هذه الدراسة يتكون من 67 مصاب بالسكري النوع الثاني و25 سيطرة اصحاء. في هذه الدراسة قسم المرضى الى ثلاث مجاميع على اساس فترة اكتشاف مرض السكري لديهم ,حيث ان نسبة المرضى الذين مدة اصابتهم بالمرض اقل من عشرة سنوات هي 34.4% وعددهم 23 مريض وهم المجموعة الاولى ,ونسبة المجموعة الثانية التي تكون مدة اصابتهم تكون اكثر من عشرة سنوات واقل من عشرين سنة هي 32.8% وعددهم 22 مريض واخيرا المجموعة الثالثة وتكون فترة الاصابة مساوية او اثر من عشرين سنة ونسبتهم 32.8% حيث كان عددهم 22 مريض ,كل العينات من مصابين بالسكري واصحاء السيطرة عمل لهم تحاليل السكري قبل الافطار بواسطة الكواشف الكيميائية وتقرأ بواسطة جهاز مقياس الطيف الضوئي بينما مستوى هرمون الكاسترين يقاس بواسطة جهاز ELISA ,ج القراءات عوملت إحصائيا باستعمال برنامج SPSS النسخة 18 وكانت هناك اختلافات معنوية بين مستوى هرمون الكاسترين ومستوى السكر في المجاميع كلهم المقسمة على اساس فترة الاصابة بداء السكري النوع الثاني .

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